YTH N6-methyladenosine RNA binding protein 2 mediated m(6)A modification of circHIPK2 promotes cellular senescence and osteoarthritis progression by inhibiting autophagy.
YTH N6-甲基腺苷 RNA 结合蛋白 2 介导的 circHIPK2 的 m(6)A 修饰通过抑制自噬促进细胞衰老和骨关节炎进展。
期刊:Molecular Biomedicine
影响因子:10.1
doi:10.1186/s43556-026-00441-4
Long Dianbo, Lin Zhencan, Li Zhiwen, Li Ming, Zhao Xiaoyi, Deng Zengfa, Jiang Zongrui, Li Wei, Zhong Yanlin, He Aishan, Xu Yiyang, Mao Guping, Kang Yan
关节炎
衰老
细胞生物学
CHIP
HIPK2
Autophagy
Senescence
自噬
细胞衰老
