日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dominant-negative TP53 mutations potentiated by the HSF1-regulated proteostasis network

显性负性TP53突变受HSF1调控的蛋白质稳态网络增强

Halim, Stephanie; Sebastian, Rebecca M; Liivak, Kristi E; Patrick, Jessica E; Hui, Tiffani; Amici, David R; Giacomelli, Andrew O; Rios, Paulina; Butty, Vincent L; Hahn, William C; Sánchez-Rivera, Francisco J; Mendillo, Marc L; Lin, Yu-Shan; Shoulders, Matthew D

Skeletal Muscle HSF1 Alleviates Age-Associated Sarcopenia and Mitochondrial Function Decline via SIRT3-PGC1α Axis.

骨骼肌 HSF1 通过 SIRT3-PGC1α 轴缓解与年龄相关的肌肉减少症和线粒体功能下降。

HSF1 and YTHDC1 enhance DNA repair under heat stress by promoting repair-associated gene expression

HSF1 和 YTHDC1 通过促进修复相关基因表达来增强热应激下的 DNA 修复。

Ding, Wenqing; Deng, Qidong; Wang, Tianyu; Liu, Ruoqian; Xiang, Yunfan; Huang, Lulu; Liu, Jun

The Novel HSF1 Inhibitor NXP800 Exhibits Robust Antitumor Activity in Hepatocellular Carcinoma

新型HSF1抑制剂NXP800在肝细胞癌中表现出强大的抗肿瘤活性

Steinmann, Sara M; Lazzari, Melania; Kleinle, Augustinus; Pischedda, Dora; Cigliano, Antonio; Galleri, Grazia; Siegmund, Heiko; Fischer, Claudia; Piscuoglio, Salvatore; Evert, Matthias; Calvisi, Diego F

Notch-1 in macrophages promoted the ischemia-reperfusion via modulating EZH2/HSF1/BRD4/SIRPα/SHP2 induced ROS and apoptosis in cardiomyocyte.

巨噬细胞中的 Notch-1 通过调节 EZH2/HSF1/BRD4/SIRPα/SHP2 诱导的 ROS 和心肌细胞凋亡,促进缺血再灌注损伤。

Tong Chengbi, Zhang JiaWei, Zuo YaJing, Yu XiaoTong, Zang ShaSha, Liu Sha

Deciphering the role of ThHSF1 in the differential expression regulation of laccase isozymes in the white-rot fungus Trametes hirsuta.

破译ThHSF1在白腐真菌Trametes hirsuta漆酶同工酶差异表达调控中的作用。

Wu Kun, Zhu Rong, Zhao Shiwen, Wang Chenkai, Zhang Xinlei, Liu Shenglong, Fang Zemin, Xiao Yazhong, Liu Juanjuan

Human DEAH-box helicase 8 regulates HSF1-mediated stress response and cancer-associated pre-mRNA splicing in tumour cells.

人类 DEAH 盒解旋酶 8 调节 HSF1 介导的应激反应和肿瘤细胞中与癌症相关的 pre-mRNA 剪接。

Tall Jennifer R, Te Poele Robert, Vasile Alexandra, Ramagiri Pradeep, Campbell James, Davies Caitlin R, Powers Marissa V, Roe Toby, Sankaran Deivendran, Wang Hannah, Mitsopoulos Konstantinos, Al-Lazikani Bissan, van Montfort Rob L M, de Billy Emmanuel, Workman Paul, Clarke Paul A

HSF1-dependent, long-range directional HSPA1 gene motion to nuclear speckles is coupled to DDX39B condensate dynamics

HSF1依赖的、长程定向的HSPA1基因向核斑点的运动与DDX39B凝聚体动力学耦合

Hernandez Gonzalez, Gabriela Andrea; Ghosh, Purnam; Kim, Jiah; Misra, Saireet; Kumar, Pradeep; Chaturvedi, Pankaj; Venkata, Neha Chivukula; Belmont, Andrew S

M102 activates both NRF2 and HSF1 transcription factor pathways and is neuroprotective in cell and animal models of amyotrophic lateral sclerosis

M102 可激活 NRF2 和 HSF1 转录因子通路,并在肌萎缩侧索硬化症的细胞和动物模型中发挥神经保护作用。

Keerie, Amy F; Martins, Raquel Rua; Allen, Chloe F; Bowden, Katie; Al Mashhadi, Sufana; Marlow, Thomas; Myszczynska, Monika; Thakur, Nikitha; Beal, Selina N; Shaw, Allan; Suresh, Shivani; McKinnon, Scott N; Cooper-Knock, Johnathan; West, Ryan J H; Bonsall, Sam; Daniel, Alex; Wells, Tyler; Kumar, Vedanth; Ellis, Brittany C S; Higgins, Maureen; Dinkova-Kostova, Albena T; Shelkovnikova, Tatyana A; Kalfus, Ira N; Shan, Ning; Shaw, Pamela J; Ferraiuolo, Laura; Mead, Richard J

Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition.

通过 p53 激活或细胞周期抑制来中断 HSF1-HSP90 轴,从而增强结直肠癌的治疗效果。

Isermann Tamara, Schneider Kim Lucia, Wegwitz Florian, De Oliveira Tiago, Conradi Lena-Christin, Volk Valery, Feuerhake Friedrich, Papke Björn, Stintzing Sebastian, Mundt Bettina, Kühnel Florian, Moll Ute M, Schulz-Heddergott Ramona