日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition

有丝分裂出口处 APC/C 活性减弱导致癌症易受 KIF18A 抑制

Colin R Gliech, Zhong Y Yeow, Daniel Tapias-Gomez, Yuchen Yang, Zhaoyu Huang, Andréa E Tijhuis, Diana Cj Spierings, Floris Foijer, Grace Chung, Nuria Tamayo, Zahra Bahrami-Nejad, Patrick Collins, Thong T Nguyen, Andres Plata Stapper, Paul E Hughes, Marc Payton, Andrew J Holland

Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation

APC/C SUMO 化修饰抑制纺锤体组装检查点并释放 APC/C 的分子机制

Stanislau Yatskevich, Jessie S Kroonen, Claudio Alfieri, Thomas Tischer, Anna C Howes, Linda Clijsters, Jing Yang, Ziguo Zhang, Kaige Yan, Alfred C O Vertegaal, David Barford

Functional Loss of ATRX and TERC Activates Alternative Lengthening of Telomeres (ALT) in LAPC4 Prostate Cancer Cells

ATRX和TERC功能丧失激活LAPC4前列腺癌细胞中的端粒替代延长(ALT)

Mindy K Graham ,Jiyoung Kim ,Joseph Da ,Jacqueline A Brosnan-Cashman ,Anthony Rizzo ,Javier A Baena Del Valle ,Lionel Chia ,Michael Rubenstein ,Christine Davis ,Qizhi Zheng ,Leslie Cope ,Michael Considine ,Michael C Haffner ,Angelo M De Marzo ,Alan K Meeker ,Christopher M Heaphy

SUMO targets the APC/C to regulate transition from metaphase to anaphase

SUMO 靶向 APC/C 来调节从中期到后期的过渡

Karolin Eifler, Sabine A G Cuijpers, Edwin Willemstein, Jonne A Raaijmakers, Dris El Atmioui, Huib Ovaa, René H Medema, Alfred C O Vertegaal

Sumoylation promotes optimal APC/C Activation and Timely Anaphase

SUMO化促进最佳的APC/C激活和及时的后期

Christine C Lee, Bing Li, Hongtao Yu, Michael J Matunis

Disruption of the anaphase-promoting complex confers resistance to TTK inhibitors in triple-negative breast cancer

后期促进复合物的破坏导致三阴性乳腺癌对 TTK 抑制剂产生耐药性

K L Thu, J Silvester, M J Elliott, W Ba-Alawi, M H Duncan, A C Elia, A S Mer, P Smirnov, Z Safikhani, B Haibe-Kains, T W Mak, D W Cescon

[(18)F]-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography of LAPC4-CR Castration-Resistant Prostate Cancer Xenograft Model in Soft Tissue Compartments

[(18)F]-氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描LAPC4-CR去势抵抗性前列腺癌异种移植模型在软组织隔室中的应用

McCall, Keisha C; Cheng, Su-Chun; Huang, Ying; Kohl, Nancy E; Tupper, Tanya; Van den Abbeele, Annick D; Zukotynski, Katherine A; Sweeney, Christopher J

Identification of SUMO-2/3-modified proteins associated with mitotic chromosomes

与有丝分裂染色体相关的 SUMO-2/3 修饰蛋白的鉴定

Caelin Cubeñas-Potts, Tharan Srikumar, Christine Lee, Omoruyi Osula, Divya Subramonian, Xiang-Dong Zhang, Robert J Cotter, Brian Raught, Michael J Matunis

Cyclin A degradation by primate cytomegalovirus protein pUL21a counters its innate restriction of virus replication

灵长类巨细胞病毒蛋白 pUL21a 降解细胞周期蛋白 A,抵消其对病毒复制的先天限制

Nicolas Caffarelli, Anthony R Fehr, Dong Yu

Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a

蛋白酶体依赖性破坏 E3 泛素连接酶后期促进复合物,导致 HCMV 蛋白 pUL21a

Anthony R Fehr, Nathaniel C Gualberto, John Paul Savaryn, Scott S Terhune, Dong Yu