日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-cell multi-omics deciphers hepatocyte dedifferentiation and illuminates maintenance strategies

单细胞多组学揭示肝细胞去分化并阐明维护策略

Jie Hao, Zhenyi Wang, Jilong Ren, Shenghao Cao, Zhongchen Xie, Jinghuan Yang, Jiachen Li, Weizhe Ding, Jie Li, Zhiqiang Han, Ye Yuan, Tang Hai, Sheng Ding, Michael Q Zhang, Minglei Shi

Increased Protein Kinase A Activity Induces Fibrolamellar Hepatocellular Carcinoma Features Independent of DNAJB1

蛋白激酶 A 活性增加可诱导纤维板层肝细胞癌特征,且不依赖于 DNAJB1

Mahsa Shirani, Solomon Levin, Bassem Shebl, David Requena, Tova M Finkelstein, Daniel S Johnson, Denise Ng, Gadi Lalazar, Søren Heissel, Peter Hojrup, Henrik Molina, Ype P de Jong, Charles M Rice, Aatur D Singhi, Michael S Torbenson, Philip Coffino, Barbara Lyons, Sanford M Simon

Author Correction: Single-cell transcriptomics stratifies organoid models of metabolic dysfunction-associated steatotic liver disease

作者更正:单细胞转录组学对代谢功能障碍相关脂肪肝的类器官模型进行分层

Anja Hess, Stefan D Gentile, Amel Ben Saad, Raza-Ur Rahman, Tim Habboub, Daniel S Pratt, Alan C Mullen

An indocyanine green-based liquid biopsy test for circulating tumor cells for pediatric liver cancer

基于吲哚菁绿的儿童肝癌循环肿瘤细胞液体活检检测

Andres F Espinoza, Pavan Kureti, Roma H Patel, Susan L Do, Saiabhiroop R Govindu, Bryan W Armbruster, Martin Urbicain, Kalyani R Patel, Dolores Lopez-Terrada, Sanjeev A Vasudevan, Sarah E Woodfield

Development of an alcoholic liver disease model for drug evaluation from human induced pluripotent stem cell-derived liver organoids

利用人类诱导性多能干细胞衍生的肝类器官开发用于药物评估的酒精性肝病模型

Zhiwei Feng, Bingrui Zhou, Qizhi Shuai, Yunliang Wei, Ning Jin, Xiaoling Wang, Hong Zhao, Zhizhen Liu, Jun Xu, Jianbing Mu, Jun Xie

A High-Throughput Microphysiological Liver Chip System to Model Drug-Induced Liver Injury Using Human Liver Organoids

利用人类肝脏类器官建立高通量微生理肝芯片系统模拟药物性肝损伤

Sophia R Meyer, Charles J Zhang, Max A Garcia, Megan C Procario, Sanghee Yoo, Amber L Jolly, Sumin Kim, Jiho Kim, Kyusuk Baek, Roland D Kersten, Robert J Fontana, Jonathan Z Sexton

C/EBPβ Coupled with E2F2 Promoted the Proliferation of hESC-Derived Hepatocytes through Direct Binding to the Promoter Regions of Cell-Cycle-Related Genes

C/EBPβ 与 E2F2 偶联通过直接结合细胞周期相关基因启动子区促进 hESC 衍生肝细胞增殖

Shoupei Liu, Jue Wang, Sen Chen, Zonglin Han, Haibin Wu, Honglin Chen, Yuyou Duan

Effects of Copper or Zinc Organometallics on Cytotoxicity, DNA Damage and Epigenetic Changes in the HC-04 Human Liver Cell Line

铜或锌有机金属化合物对 HC-04 人肝细胞系的细胞毒性、DNA 损伤和表观遗传变化的影响

Daniel Desaulniers, Gu Zhou, Andrew Stalker, Cathy Cummings-Lorbetskie

Undifferentiated Induced Pluripotent Stem Cells as a Genetic Model for Nonalcoholic Fatty Liver Disease

未分化诱导性多能干细胞作为非酒精性脂肪性肝病的遗传模型

Antonio Muñoz, Elizabeth Theusch, Yu-Lin Kuang, Gilbert Nalula, Caitlin Peaslee, Gabriel Dorlhiac, Markita P Landry, Aaron Streets, Ronald M Krauss, Carlos Iribarren, Aras N Mattis, Marisa W Medina

The Human Liver-Expressed Lectin CD302 Restricts Hepatitis C Virus Infection

人类肝脏表达的凝集素 CD302 可限制丙型肝炎病毒感染

Birthe Reinecke, Nicola Frericks, Chris Lauber, Katja Dinkelborg, Alina Matthaei, Florian W R Vondran, Patrick Behrendt, Sibylle Haid, Richard J P Brown, Thomas Pietschmann