ICAM1相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Targeting the Notch1-YY1-ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8(+) T-Cell-Driven Cancer Cell Pyroptosis.

靶向 Notch1-YY1-ICAM1 信号轴可激活 CD8(+) T 细胞驱动的癌细胞焦亡，从而增强免疫疗法在 HCC 中的疗效。

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202512845

Zhu Ke, Zhang Fa-Peng, Qin Chao, Song Zhi-Xiao, Yang Cai-Ni, Lin Shu-Sheng, Yu Xian-Huan, Wu Wen-Rui, Liu Chao-Qun, Liu Chao, Xu Lei-Bo

细胞生物学

免疫/内分泌

发表日期：2026

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Mixed-mobility supported lipid bilayers uncover the role of immobilized ICAM1 on T cell activation and immune synapse organization

混合迁移率支持的脂质双层揭示了固定化ICAM1在T细胞活化和免疫突触组织中的作用

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2530126123

Leithner, Alexander; Kvalvaag, Audun; Mitra, Tanmay; Valvo, Salvatore; Dada, Hannah; Compeer, Ewoud; Barton, Michael I; Eguiguren, Sofia Bustamante; Jenkins, Edward; Lagerholm, Christoffer; Dushek, Omer; Dustin, Michael L

细胞生物学

免疫/内分泌

发表日期：2026

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A broad kinase inhibitor library live cell imaging screen using liver, kidney and cardiac hiPSC-ICAM1-eGFP reporter lineages identifies liabilities for TNFα pathway modulation

利用肝脏、肾脏和心脏hiPSC-ICAM1-eGFP报告基因谱系进行广泛的激酶抑制剂库活细胞成像筛选，鉴定出TNFα通路调控的潜在靶点

期刊:Archives of Toxicology

影响因子:6.9

doi:10.1007/s00204-025-04226-6

Vlasveld, Matthijs; van den Berk, Linda; Piñero, Janet; Helmke, Palle S; Ecker, Gerhard F; van Rossom, Rob; Schmidt, Bela Z; Verfaillie, Catherine; Tassis, Konstantinos; Callegaro, Giulia; Bouwman, Peter; van de Water, Bob

细胞生物学

发表日期：2026

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Associations of the ICAM1 p.K56M HFpEF Risk Variant With Pericardial Adiposity and the Inflammatory Proteome

ICAM1 p.K56M HFpEF 风险变异与心包脂肪和炎症蛋白组的关联

期刊:Circulation-Genomic and Precision Medicine

影响因子:5.5

doi:10.1161/CIRCGEN.125.005475

Aneja, Anushree; Culler, Kasen L; Ding, Jingzhong; Taylor, Kent D; Shah, Sanjiv J; Rasmussen-Torvik, Laura; Patel, Ravi B

发表日期：2026

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Jurkat T-Cell Antigen-Independent Elimination of PMA-Activated Neuroblastoma Cells Is Triggered by CCL2/CCR2, Depends Upon Lipid Raft LFA1/ICAM1 Immune Synapses, Is Mediated by m-TRAIL and Is Augmented by the TrkAIII Oncoprotein

Jurkat T细胞抗原非依赖性清除PMA激活的神经母细胞瘤细胞是由CCL2/CCR2触发的，依赖于脂筏LFA1/ICAM1免疫突触，由m-TRAIL介导，并被TrkAIII癌蛋白增强。

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms27041970

Sbaffone, Maddalena; Martelli, Ilaria; Cipriani, Paola; Farina, Antonietta Rosella; Cappabianca, Lucia Annamaria; Mackay, Andrew Reay

细胞生物学

免疫/内分泌

发表日期：2026

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Nordihydroguaiaretic acid attenuates TNFα-dependent intercellular adhesion molecule-1 expression in cultured human umbilical vein endothelial cells via targeting TNFα-PI3K-NF-κB-ICAM1 pathway

二氢愈创木酸通过靶向TNFα-PI3K-NF-κB-ICAM1通路，减弱培养的人脐静脉内皮细胞中TNFα依赖的细胞间黏附分子-1（ICAM-1）的表达。

期刊:BMC Microbiology

影响因子:4.2

doi:10.1186/s12866-026-04947-3

Moreno-León, Alejandro; López-Morales, Ane; Höfle, Ursula; Barral, Marta; Majó, Natàlia; Lavín, José Luis; Mukherjee, Tapan Kumar; Malik, Parth; Singh, Raj; Haribhai Patel, Vishal; Kumar, Raman

细胞生物学

发表日期：2026

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CD38 overexpression drives glioblastoma progression via L1CAM/ICAM1/JAK-STAT-Driven tumor microenvironment rewiring.

CD38 过表达通过 L1CAM/ICAM1/JAK-STAT 驱动的肿瘤微环境重塑促进胶质母细胞瘤进展。

期刊:Translational Oncology

影响因子:4.1

doi:10.1016/j.tranon.2026.102758

Norouzi Saeed, Aulakh Sonikpreet

细胞生物学

肿瘤微环境

发表日期：2026

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Spatial atlas of gastric cancer reveals macrophage-driven stromal activation via ICAM1⁺ smooth muscle cells

胃癌空间图谱揭示巨噬细胞通过ICAM1⁺平滑肌细胞驱动的基质活化

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/s12885-026-15647-6

Cheng, Kang; Xu, Jingquan; Yang, Jianlei; Zhang, Zili

细胞生物学

免疫/内分泌

发表日期：2026

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Nordihydroguaiaretic acid attenuates TNFα-dependent intercellular adhesion molecule-1 expression in cultured human umbilical vein endothelial cells via targeting TNFα-PI3K-NF-κB-ICAM1 pathway

二氢愈创木酸通过靶向TNFα-PI3K-NF-κB-ICAM1通路，减弱培养的人脐静脉内皮细胞中TNFα依赖的细胞间黏附分子-1（ICAM-1）的表达。

期刊:Avicenna Journal of Phytomedicine

影响因子:2.2

doi:10.22038/ajp.2025.26057

Mukherjee, Tapan Kumar; Malik, Parth; Singh, Raj; Haribhai Patel, Vishal; Kumar, Raman

细胞生物学

发表日期：2026

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Inhibition of ICAM1 diminishes stemness and enhances antitumor immunity in glioblastoma via β-catenin/PD-L1 signaling

抑制ICAM1可通过β-catenin/PD-L1信号通路降低胶质母细胞瘤的干性并增强其抗肿瘤免疫力。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-63796-2

Meixia Guo # ，Zheng Yuan # ，Xiong Jin # ，Xinyu Li ，Yilin Deng ，Shuchang Zhou ，Rui Niu ，Joonbeom Bae ，Jong Bae Park ，Bingyang Shi ，Jinlong Yin

免疫/内分泌

发表日期：2025

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