Dysregulated Lipid Synthesis by Oncogenic IDH1 Mutation Is a Targetable Synthetic Lethal Vulnerability
致癌性IDH1突变导致的脂质合成失调是一种可靶向的合成致死脆弱性
期刊:Cancer Discovery
影响因子:29.7
doi:10.1158/2159-8290.CD-21-0218
Daniel Thomas ,Manhong Wu ,Yusuke Nakauchi ,Ming Zheng ,Chloe A L Thompson-Peach ,Kelly Lim ,Niklas Landberg ,Thomas Köhnke ,Nirmal Robinson ,Satinder Kaur ,Monika Kutyna ,Melissa Stafford ,Devendra Hiwase ,Andreas Reinisch ,Gary Peltz ,Ravindra Majeti