日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tubule-Derived IFN-α Promotes GSDMD-Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation.

肾小管衍生的 IFN-α 促进 GSDMD 介导的巨噬细胞焦亡,通过 JAK2/STAT2 激活驱动肾脏炎症和纤维化。

Xu Yiping, Wang Yating, Jiang Siming, Li Yi, Li Guanglan, Liu Yuchu, Li Siyuan, Zhou Yiming, Liu Qinghua, Zhou Yi, Chen Wei, Li Hongyu, Mao Haiping

Engineered suppressor T cells overexpressing IFN-α and PD-L1 inhibit GVHD but retain GVL effects in mice

经基因工程改造的抑制性T细胞过表达IFN-α和PD-L1,可抑制小鼠的移植物抗宿主病(GVHD),但仍保留移植物抗白血病(GVL)效应。

Tian, Yuanyuan; Jia, Bei; Lee, Che Young; Huang, Qingrong; Zhao, Chenchen; Abraham, Ciril; Mo, Wenbin; Zhang, Yongping; Chen, Mimi; Wang, Ying; Blazar, Bruce R; Zheng, Hong; Zhang, Yi

Plasma EV miR-186-5p as an Early Biomarker and Regulator of IFN-α-Mediated Oxidative and β-Cell Dysfunction in Prediabetes

血浆细胞外囊泡 miR-186-5p 作为糖尿病前期 IFN-α 介导的氧化应激和 β 细胞功能障碍的早期生物标志物和调节因子

Park, Jae-Hyung; Nguyen, Thi Nhi; Shim, Hye Min; Bae, Yun-Ui; Yu, Gyeong Im; Kang, Junho; Ha, Eun Yeong; Cho, Hochan

MERS-CoV and SARS-CoV-1 proteins inhibit the IFN-α JAK/STAT pathway of epithelial cells, via IFN-λ-induced USP18

MERS-CoV 和 SARS-CoV-1 蛋白通过 IFN-λ 诱导的 USP18 抑制上皮细胞的 IFN-α JAK/STAT 通路。

Zhang, Yamei; Stevenson, Nigel J

Can Phagocytosis, Neutrophil Extracellular Traps, and IFN-α Production in Systemic Lupus Erythematosus Be Simultaneously Modulated? A Pharmacological Perspective

系统性红斑狼疮中吞噬作用、中性粒细胞胞外陷阱和IFN-α产生能否同时受到调控?药理学视角

Seidlberger, Stephanie; Huti, Sindi; Castañeda, Santos; Schirmer, Michael; Fenkart, Julian; Wietzorrek, Georg; Santos-Sierra, Sandra

Early mucosal IFN-α, IP-10, and IL-1RA and synchronized mucosal and systemic immune responses mediate COVID-19 disease progression

早期黏膜IFN-α、IP-10和IL-1RA以及同步的黏膜和全身免疫反应介导COVID-19疾病进展。

Agrawal, Mona; Flores-Torres, Armando S; Franks, John S; Lang, Sarah Y; Fabrizio, Thomas P; McNair, Kristin E; Boywid, Laura V; Blair, Ashley J; Hundman, Chloe N; Hysmith, Nicholas D; Whitt, Michael A; Keating, Rachael; Thomas, Paul G; Webby, Richard J; Green, Amanda M; Smallwood, Heather S

Dynamic changes in TREX1 and LGALS9 mRNA levels in PBMCs predict HBsAg clearance and treatment responses to Peg-IFN-α therapy in HBeAg-negative chronic hepatitis B patients

外周血单核细胞中TREX1和LGALS9 mRNA水平的动态变化可预测HBeAg阴性慢性乙型肝炎患者HBsAg的清除情况以及对聚乙二醇干扰素α(Peg-IFN-α)治疗的反应。

Pang, Hao; Jiang, Jinhong; Fu, Xinglin; Qin, Bo

Exploring the effects of IFN-τ on LPS-induced endometritis in cows based on transcriptomics.

基于转录组学探索 IFN-α 对 LPS 诱导的母牛子宫内膜炎的影响。

A highly prevalent lupus risk haplotype increases IRF7-dependent induction of IFN-α, enhancing antiviral defense and exacerbating autoimmunity

一种高发的狼疮风险单倍型会增加IRF7依赖的IFN-α诱导,从而增强抗病毒防御并加剧自身免疫。

Virolainen, Samuel J; Creighton, Kathryn; Dashtiahangar, Maryam; Krishnamurthy, Durga; Parks, Lois; Forney, Carmy; Ampadu, Britney; Rudrapatna, Akshata N; Dunn, Katelyn A; Parameswaran, Sreeja; Hesse, Hayley K; Chen, Xiaoting; VonHandorf, Andrew; Edsall, Lee E; Yin, Cailing; Lynch, Arthur; Gittens, Olivia E; Diouf, Arame A; Jones, Sydney H; Hass, Matthew; Javier, Ellen; Donmez, Omer A; Keddari, Yasine; Danzinger, Oded; Seelamneni, Harsha; Namjou-Khales, Bahram; Ainsworth, Hannah C; Comeau, Mary E; Marion, Miranda C; Glenn, Stuart B; Nath, Swapan K; Freedman, Barry I; Tsao, Betty P; Kamen, Diane L; Brown, Elizabeth E; Gilkeson, Gary S; Alarcón, Graciela S; Reveille, John D; James, Judith A; Criswell, Lindsey A; Vilá, Luis M; Alarcón-Riquelme, Marta E; Petri, Michelle; Scofield, R Hal; Kimberly, Robert P; Ramsey-Goldman, Rosalind; Bae, Sang-Cheol; Graham, Deborah Cunninghame; Vyse, Timothy J; Guthridge, Joel M; Gaffney, Patrick M; Langefeld, Carl D; Kelly, Jennifer A; Kaufman, Kenneth M; Sivils, Kathy; Harley, John B; Shen, Nan; Lawson, Lucinda P; Baglaenko, Yuriy; Miraldi, Emily R; Rosenberg, Brad R; Siggers, Trevor; Waggoner, Stephen N; Weirauch, Matthew T; Kottyan, Leah C

The type 1 diabetes candidate genes PTPN2 and BACH2 regulate the IFN-α-induced crosstalk between JAK/STAT and MAPKs pathways in human beta cells.

1 型糖尿病候选基因 PTPN2 和 BACH2 调节人类 β 细胞中 IFN-α 诱导的 JAK/STAT 和 MAPKs 通路之间的串扰。

Roca-Rivada Arturo, Oliveira Junior Garcia, Martin-Vazquez Eugenia, Coomans de Brachène Alexandra, Yi Xiaoyan, Costa-Júnior Jose Maria, Zimath Priscila L, Van Goethem Flore, Pattou François, Kerr-Conte Julie, Buemi Antoine, Mourad Nizar I, Eizirik Decio L