日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lysophosphatidic Acid Synergizes With 1,25-Dihydroxyvitamin D to Promote Fibroblast Growth Factor-23 Synthesis via MAPK Signaling and Induction of the IL12A Gene.

溶血磷脂酸与 1,25-二羟基维生素 D 协同作用,通过 MAPK 信号传导和 IL12A 基因的诱导促进成纤维细胞生长因子-23 的合成。

Ay Birol, Cyr Sajin Marcus, Iwasaki Yorihiro, Hill Elizabeth, Rhee Eugene P, Singh Nevil J, Simic Petra, Bastepe Murat

JunB is required for CD8+ T cell responses to acute infections

JunB是CD8+ T细胞对急性感染产生反应所必需的。

Shukla Sarkar ,Naoyuki Taira ,Tsung-Han Hsieh ,Hsiao-Chiao Chien ,Masato Hirota ,Shin-Ichi Koizumi ,Daiki Sasaki ,Miho Tamai ,Yu Seto ,Mio Miyagi ,Hiroki Ishikawa

IL-12 drives the expression of the inhibitory receptor NKG2A on human tumor-reactive CD8 T cells

IL-12驱动人肿瘤反应性CD8 T细胞上抑制性受体NKG2A的表达

Olivier Fesneau ,Kimberly A Samson ,Wesley Rosales ,Bretton Jones ,Tarsem Moudgil ,Bernard A Fox ,Venkatesh Rajamanickam ,Thomas Duhen

Mediation of antitumor activity by AZD4820 oncolytic vaccinia virus encoding IL-12

编码 IL-12 的 AZD4820 溶瘤痘苗病毒介导抗肿瘤活性

Cheyne Kurokawa, Sonia Agrawal, Abhisek Mitra, Elena Galvani, Shannon Burke, Ankita Varshine, Raymond Rothstein, Kevin Schifferli, Noel R Monks, Johann Foloppe, Nathalie Silvestre, Eric Quemeneur, Christelle Demeusoit, Patricia Kleinpeter, Puja Sapra, Carl Barrett, Scott A Hammond, Elizabeth J Kelly

Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein-Protein Interaction

基于米诺环素诱导的蛋白质-蛋白质相互作用破坏的小分子调控系统

Ram Jha ,Alexander Kinna ,Alastair Hotblack ,Reyisa Bughda ,Anna Bulek ,Isaac Gannon ,Tudor Ilca ,Christopher Allen ,Katarina Lamb ,Abigail Dolor ,Ian Scott ,Farhaan Parekh ,James Sillibourne ,Shaun Cordoba ,Shimobi Onuoha ,Simon Thomas ,Mathieu Ferrari ,Martin Pule

Investigation of thermal conductivity and thermal performance of heat pipes by structurally designed copolymer stabilized ZnO nanofluid

通过结构设计的共聚物稳定的 ZnO 纳米流体研究热管的导热系数和热性能

K S Pavithra, Vinay Parol, A Brusly Solomon, M P Yashoda

Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation

早期IFNβ分泌决定了TLR4激活后下游IL-12p70反应的差异。

Celine Posseme ,Alba Llibre ,Bruno Charbit ,Vincent Bondet ,Vincent Rouilly ,Violaine Saint-André ,Jeremy Boussier ,Jacob Bergstedt ,Nikaïa Smith ,Liam Townsend ,Jamie A Sugrue ,Clíona Ní Cheallaigh ,Niall Conlon ,Maxime Rotival ,Michael S Kobor ,Estelle Mottez ,Stanislas Pol ,Etienne Patin ,Matthew L Albert ,Lluis Quintana-Murci ,Darragh Duffy

Very-low-carbohydrate diet enhances human T-cell immunity through immunometabolic reprogramming

极低碳水化合物饮食通过免疫代谢重编程增强人体T细胞免疫力

Simon Hirschberger ,Gabriele Strauß ,David Effinger ,Xaver Marstaller ,Alicia Ferstl ,Martin B Müller ,Tingting Wu ,Max Hübner ,Tim Rahmel ,Hannah Mascolo ,Nicole Exner ,Julia Heß ,Friedrich W Kreth ,Kristian Unger ,Simone Kreth

Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models

在小鼠肿瘤模型中,膜锚定白细胞介素-12 T细胞疗法可增强疗效并减少全身细胞因子暴露。

Ling Zhang,John S Davies,Carylinda Serna,Zhiya Yu,Nicholas P Restifo,Steven A Rosenberg,Richard A Morgan,Christian S Hinrichs

Aberrant Th2 Immune Responses Are Associated With a Reduced Frequency of IL-35-Induced Regulatory T Cells After Allergen Exposure in Patients With Allergic Asthma

过敏性哮喘患者接触过敏原后,异常的 Th2 免疫反应与 IL-35 诱导的调节性 T 细胞频率降低有关

Wei Wang, Chaojie Wei, Zhenshun Cheng, Jiong Yang