INO80相关文献与解析，生知库 | 链接生命科学的每一步

Loss of function of the chromatin remodeling gene INO80D leads to neurogenic features of schizophrenia

染色质重塑基因 INO80D 功能丧失会导致精神分裂症的神经源性特征

期刊:Proceedings of the National Academy of Sciences of the United States of America

Sunshine, Anna B; Gulsuner, Suleyman; Williams, C Andrew; Sarchi, Martina; Chen, Robert Y; Cavanaugh, Christopher; Hesson, Jennifer; Mathieu, Julie; Young, Jessica E; McClellan, Jon M; King, Mary-Claire

esBAF and INO80C fine-tune subcompartments and differentially regulate enhancer-promoter interactions

esBAF 和 INO80C 精细调控亚区室，并对增强子-启动子相互作用进行差异性调控。

期刊:Genetics

影响因子:5.1

doi:10.1093/genetics/iyag037

Bonilla, Braulio; Patty, Benjamin J; Sambare, Snehal V; Dekker, Job; Fazzio, Thomas G; Hainer, Sarah J

INO80 regulates promoter-associated R-loops to coordinate transcription and maintain genome stability in embryonic stem cells.

INO80 调节启动子相关的 R 环，以协调转录并维持胚胎干细胞的基因组稳定性。

期刊:Biological Research

影响因子:4.6

doi:10.1186/s40659-025-00666-7

Lim Hoseong, Kwon Ohbeom, La Hyeonwoo, Lee Hyeonji, Lee Heeji, Do Jeong-Tae, Song Hyuk, Choi Youngsok, Hong Kwonho

The Ies6 subunit is essential for INO80-mediated nucleosome organization

Ies6亚基对于INO80介导的核小体组织至关重要。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-026-40504-8

Singh, Ashish Kumar; Mueller-Planitz, Felix

INO80

发表日期：2026

文献求助收藏

Autoinhibition imposed by a large conformational switch of INO80 regulates nucleosome positioning

INO80构象的大幅变化所引发的自身抑制作用调控核小体的定位。

期刊:Science

影响因子:45.8

doi:10.1126/science.adr3831

Kaur, Upneet; Wu, Hao; Cheng, Yifan; Narlikar, Geeta J

INO80/SWR remodelers regulate Pol II transcription through BRD2 and chromatin landscape.

INO80/SWR 重塑因子通过 BRD2 和染色质结构调控 Pol II 转录。

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkaf892

Liu Meitong, Xu Qiqin, Wang Hui, Ji Xiong

Conformational switching of Arp5 subunit regulates INO80 chromatin remodeling.

Arp5亚基的构象转换调节INO80染色质重塑。

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkae1187

INO80

发表日期：2025

文献求助收藏

Loss of Nup155 promotes high fructose-driven podocyte senescence by inhibiting INO80 mRNA nuclear export

Nup155 的缺失通过抑制 INO80 mRNA 的核输出，促进高果糖诱导的足细胞衰老。

期刊:Journal of Advanced Research

影响因子:13

doi:10.1016/j.jare.2024.08.007

Chen, Li; Xu, Tangdi; Wang, Zixuan; Wang, Chengzhi; Fang, Lei; Kong, Lingdong

Erratum for the Research Article "ACTR5 controls CDKN2A and tumor progression in an INO80-independent manner" by X. Xu et al

X. Xu 等人的研究论文“ACTR5 以 INO80 非依赖的方式控制 CDKN2A 和肿瘤进展”的勘误

期刊:Science Advances

影响因子:12.5

doi:10.1126/sciadv.aec5118

Recognition and remodelling of nucleosomes and hexasomes by the human INO80 complex.

人类 INO80 复合物对核小体和六聚体的识别和重塑。

Loss of function of the chromatin remodeling gene INO80D leads to neurogenic features of schizophrenia

染色质重塑基因 INO80D 功能丧失会导致精神分裂症的神经源性特征

esBAF and INO80C fine-tune subcompartments and differentially regulate enhancer-promoter interactions

esBAF 和 INO80C 精细调控亚区室，并对增强子-启动子相互作用进行差异性调控。

INO80 regulates promoter-associated R-loops to coordinate transcription and maintain genome stability in embryonic stem cells.

INO80 调节启动子相关的 R 环，以协调转录并维持胚胎干细胞的基因组稳定性。

The Ies6 subunit is essential for INO80-mediated nucleosome organization

Ies6亚基对于INO80介导的核小体组织至关重要。

Autoinhibition imposed by a large conformational switch of INO80 regulates nucleosome positioning

INO80构象的大幅变化所引发的自身抑制作用调控核小体的定位。

INO80/SWR remodelers regulate Pol II transcription through BRD2 and chromatin landscape.

INO80/SWR 重塑因子通过 BRD2 和染色质结构调控 Pol II 转录。

Conformational switching of Arp5 subunit regulates INO80 chromatin remodeling.

Arp5亚基的构象转换调节INO80染色质重塑。

Loss of Nup155 promotes high fructose-driven podocyte senescence by inhibiting INO80 mRNA nuclear export

Nup155 的缺失通过抑制 INO80 mRNA 的核输出，促进高果糖诱导的足细胞衰老。

Erratum for the Research Article "ACTR5 controls CDKN2A and tumor progression in an INO80-independent manner" by X. Xu et al

X. Xu 等人的研究论文“ACTR5 以 INO80 非依赖的方式控制 CDKN2A 和肿瘤进展”的勘误