LATS2相关文献与解析，生知库 | 链接生命科学的每一步

Immunoexpression profile of LATS2 and YAP1 and its clinicopathological relevance in oral tongue squamous cell carcinoma

LATS2和YAP1的免疫表达谱及其在口腔舌鳞状细胞癌中的临床病理意义

期刊:Oral and Maxillofacial Surgery-Heidelberg

Rocha Torres, Ondina Karla Mousinho; Borges, André Luis Alves; da Costa, Lucas Melo; Colares, Débora Frota; da Silveira, Éricka Janine Dantas; da Miguel, Márcia Cristina Costa

Retraction Note: Circular RNA circ_103820 suppresses lung cancer tumorigenesis by sponging miR-200b-3p to release LATS2 and SOCS6

撤稿声明：环状RNA circ_103820通过吸附miR-200b-3p释放LATS2和SOCS6来抑制肺癌的肿瘤发生。

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-025-08272-x

Chi, Yongbin; Zheng, Wenlong; Bao, Guangyu; Wu, Lifeng; He, Xiaoxue; Gan, Ruyi; Shen, Yan; Yin, Xudong; Jin, Mingming

Inhibition of Hippo Signaling Through Ablation of Lats1 and Lats2 Protects Against Cognitive Decline in 5xFAD Mice via Increasing Neuronal Resilience Against Ferroptosis

通过敲除Lats1和Lats2抑制Hippo信号通路，可增强神经元抵抗铁死亡的能力，从而保护5xFAD小鼠免受认知衰退的影响。

期刊:Aging Cell

影响因子:8

doi:10.1111/acel.70218

Robert C Evans ，Nawab John Dar ，Liuji Chen ，Ren Na ，Jason C O'Connor ，Jing Jiang ，Siyuan Zheng ，Qitao Ran

Discovery and Optimization of LATS1 and LATS2 Kinase Inhibitors for Use in Regenerative Medicine

LATS1和LATS2激酶抑制剂的发现和优化及其在再生医学中的应用

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.5c01027

Morris, Patrick J; Duveau, Damien Y; Ceribelli, Michele; Tosto, Frances Anne; Love, Dara N; Scherer, Bridget S; Tao, Dingyin; Fang, Yuhong; Evsen, Lale; Kotler, Samuel A; LeClair, Christopher A; Rai, Ganesha; Thomas, Craig J; Hoyt, Scott B

[Expression of Concern] miR‑135b, upregulated in breast cancer, promotes cell growth and disrupts the cell cycle by regulating LATS2

【关注事项】miR-135b在乳腺癌中高表达，通过调控LATS2促进细胞生长并扰乱细胞周期。

期刊:International Journal of Oncology

影响因子:4.9

doi:10.3892/ijo.2025.5802

Hua, Kaiyao; Jin, Jiali; Zhao, Junyong; Song, Jialu; Song, Hongming; Li, Dengfeng; Maskey, Niraj; Zhao, Bingkun; Wu, Chenyang; Xu, Hui; Fang, Lin

YAP1 promotes adipogenesis by regulating the negative feedback mechanism of the Hippo signaling pathway via LATS2

YAP1通过LATS2调节Hippo信号通路的负反馈机制，从而促进脂肪生成。

期刊:Zoological Research

影响因子:4.7

doi:10.24272/j.issn.2095-8137.2024.404

Zhou, Mei; Zhao, Yue-Qi; Yan, Wei; Fu, Xue-Feng; Zhang, Li-Hui; Zhang, Hong-Yan; Bao, Ge-Gen-Tu-Ya; Liu, Dong-Jun

Correction: Knockdown of PVT1 inhibits cell proliferation in luminal and basal-like breast cancer subtypes by activating LATS2/Hippo signaling pathway

更正：PVT1 的敲低通过激活 LATS2/Hippo 信号通路抑制管腔型和基底样乳腺癌亚型的细胞增殖。

期刊:World Journal of Surgical Oncology

影响因子:2.5

doi:10.1186/s12957-025-03995-9

Zhang, Hai-Bo; Zeng, Ying; Wang, Guo

Knockdown of PVT1 inhibits cell proliferation in luminal and basal-like breast cancer subtypes by activating LATS2/Hippo signaling pathway

敲低PVT1可通过激活LATS2/Hippo信号通路抑制管腔型和基底样乳腺癌亚型的细胞增殖

期刊:World Journal of Surgical Oncology

影响因子:2.5

doi:10.1186/s12957-025-03944-6

Zhang, Hai-Bo; Zeng, Ying; Wang, Guo

[Retracted] miR-372 promotes breast cancer cell proliferation by directly targeting LATS2

【已撤稿】miR-372通过直接靶向LATS2促进乳腺癌细胞增殖

期刊:

影响因子:

doi:10.3892/etm.2025.12926

Cheng, Xueyuan; Chen, Junqiang; Huang, Zhong

Regulation of tension-dependent localization of LATS1 and LATS2 to adherens junctions

LATS1和LATS2在黏着连接处的张力依赖性定位调控

Immunoexpression profile of LATS2 and YAP1 and its clinicopathological relevance in oral tongue squamous cell carcinoma

LATS2和YAP1的免疫表达谱及其在口腔舌鳞状细胞癌中的临床病理意义

Retraction Note: Circular RNA circ_103820 suppresses lung cancer tumorigenesis by sponging miR-200b-3p to release LATS2 and SOCS6

撤稿声明：环状RNA circ_103820通过吸附miR-200b-3p释放LATS2和SOCS6来抑制肺癌的肿瘤发生。

Inhibition of Hippo Signaling Through Ablation of Lats1 and Lats2 Protects Against Cognitive Decline in 5xFAD Mice via Increasing Neuronal Resilience Against Ferroptosis

通过敲除Lats1和Lats2抑制Hippo信号通路，可增强神经元抵抗铁死亡的能力，从而保护5xFAD小鼠免受认知衰退的影响。

Discovery and Optimization of LATS1 and LATS2 Kinase Inhibitors for Use in Regenerative Medicine

LATS1和LATS2激酶抑制剂的发现和优化及其在再生医学中的应用

[Expression of Concern] miR‑135b, upregulated in breast cancer, promotes cell growth and disrupts the cell cycle by regulating LATS2

【关注事项】miR-135b在乳腺癌中高表达，通过调控LATS2促进细胞生长并扰乱细胞周期。

YAP1 promotes adipogenesis by regulating the negative feedback mechanism of the Hippo signaling pathway via LATS2

YAP1通过LATS2调节Hippo信号通路的负反馈机制，从而促进脂肪生成。

Correction: Knockdown of PVT1 inhibits cell proliferation in luminal and basal-like breast cancer subtypes by activating LATS2/Hippo signaling pathway

更正：PVT1 的敲低通过激活 LATS2/Hippo 信号通路抑制管腔型和基底样乳腺癌亚型的细胞增殖。

Knockdown of PVT1 inhibits cell proliferation in luminal and basal-like breast cancer subtypes by activating LATS2/Hippo signaling pathway

敲低PVT1可通过激活LATS2/Hippo信号通路抑制管腔型和基底样乳腺癌亚型的细胞增殖

[Retracted] miR-372 promotes breast cancer cell proliferation by directly targeting LATS2

【已撤稿】miR-372通过直接靶向LATS2促进乳腺癌细胞增殖