日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HPF1 regulates the formation of FUS-dependent compartments by PARP1 and PARP2 activation on damaged DNA

HPF1通过激活受损DNA上的PARP1和PARP2来调控FUS依赖性区室的形成。

Singatulina, Anastasia S; Sukhanova, Maria V; Hamon, Loic; Kutuzov, Mikhail M; Pastré, David; Lavrik, Olga I

PARP1 and PARP2 are dispensable for DNA repair by microhomology-mediated end-joining at double-ended DSBs.

PARP1 和 PARP2 对于通过微同源介导的末端连接修复双端 DSB 的 DNA 损伤来说并非必需。

Ortega Raquel, Taylor Erin R, Whitehead Sophie M, Danhorn Thomas, Bitler Benjamin G, Arnoult Nausica

ARP2/3 complex mediates the neuropathology of PTEN-deficient human neural cells downstream of mTORC1 and mTORC2 hyperactivation

ARP2/3复合物通过mTORC1和mTORC2过度激活,介导PTEN缺陷型人类神经细胞的神经病理学变化。

Dhaliwal, Navroop K; Weng, Octavia Yifang; Tian, Ai; Aggarwal, Aditi; Ahmed, Mai; Sun, Guoria; Bhattacharya, Afrin; Choi, Wendy W Y; Nishimura, Haruka; Chakraborty, Pragnya; Dong, Xiaoxue; Wu, Yuncheng; Wilson, Michael D; Wang, Lu-Yang; Parada, Luis F; Muffat, Julien; Li, Yun

The Arp2/3 complex controls the development of homeostatic microglia.

Arp2/3复合物控制着稳态小胶质细胞的发育。

Safaiyan Shima, Frosch Maximilian, Bickel Tom, Monaco Gianni, Dvir Roie, Madry Christian, Bosch Lance Fredrick Pahutan, Kierdorf Katrin, Innocenti Metello, Priller Josef, Prinz Marco, Lämmermann Tim

ARPC2 Promotes Pulmonary Fibrosis by Regulating MRTFA Activity Independent of the Canonical ARP2/3 Complex.

ARPC2 通过调节 MRTFA 活性促进肺纤维化,且该过程独立于经典的 ARP2/3 复合物。

Du Eun Jo, Kim Hyunseong, Bae Seo-Gyeong, An Sihyeon, Ryoo Kanghyun

AVIL promotes osteosarcoma progression and cisplatin resistance via ARP2/3-mediated DNA damage repair

AVIL通过ARP2/3介导的DNA损伤修复促进骨肉瘤进展和顺铂耐药性。

Chen, Zhenyi; Tang, Guozhu; Lv, Xuan; Ding, Guoqing; Huang, Mingyang; Chen, Zhe; Dai, Shuo; Liu, Huilin; Zhang, Sheng; Cai, Lin

(1)H, (13)C and (15)N resonance assignments of the N-terminal intrinsically disordered region and WGR domain of human PARP2

人PARP2 N端固有无序区和WGR结构域的(1)H、(13)C和(15)N共振归属

Virk, Rajbinder K; Kim, Tae Hun

An atypical Arp2/3 complex is required for Plasmodium DNA segregation and malaria transmission.

非典型的 Arp2/3 复合物是疟原虫 DNA 分离和疟疾传播所必需的

Hentzschel Franziska, Jewanski David, Sokolowski Yvonne, Agarwal Pratika, Kraeft Anna, Hildenbrand Kolja, Dorner Lilian P, Singer Mirko, Marti Matthias, Frischknecht Friedrich

XRCC1 mediates PARP1- and PAR-dependent recruitment of PARP2 to DNA damage sites

XRCC1介导PARP1和PAR依赖性的PARP2募集至DNA损伤位点。

Xiaohui Lin ,Kay Sze Karina Leung ,Kaitlynn F Wolfe ,Nicolas Call ,Seema Khattri Bhandari ,Xiaoyu Huang ,Brian J Lee ,Alan E Tomkinson ,Shan Zha

A PARP2 active site helix melts to permit DNA damage-induced enzymatic activation

PARP2活性位点螺旋解开,从而允许DNA损伤诱导的酶激活。

Emily S Smith-Pillet ,Ramya Billur ,Marie-France Langelier ,Tanaji T Talele ,John M Pascal ,Ben E Black