LRP1相关文献与解析，生知库 | 链接生命科学的每一步

Alpinetin Nanoparticles Alleviate Optic Nerve Injury Induced by Acute Glaucoma via LRP1-PPARÎ³ Mediated Regulation of Microglial Lipid Metabolism.

高山黄素纳米颗粒通过 LRP1-PPARγ 介导的小胶质细胞脂质代谢调节来缓解急性青光眼引起的视神经损伤。

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202513270

The LRP1-SHP2 pathway regulates TRPV1 sensitivity in the peripheral nervous system: Insights from amyloid beta 1-42 modulation.

LRP1-SHP2 通路调节外周神经系统中的 TRPV1 敏感性：来自淀粉样蛋白 β 1-42 调节的启示。

期刊:Journal of Advanced Research

影响因子:13

doi:10.1016/j.jare.2025.03.005

Hwang Sung-Min, Roh Jueun, Go Eun Jin, Pan Jing-Ying, Park Jaeik, Rahman Mahbubur, Jung YunJae, Lee Sun-Ho, Han Inbo, Chung Gehoon, Lee Sang Hoon, Berta Temugin, Park Chul-Kyu, Kim Yong Ho

MST1 promotes microglial pyroptosis and neuroinflammation in alzheimer's disease by regulating the novel DPP8/NLRP1/Caspase-1/GSDMD-N axis.

MST1 通过调节新型 DPP8/NLRP1/Caspase-1/GSDMD-N 轴促进阿尔茨海默病中的小胶质细胞焦亡和神经炎症。

期刊:Journal of Neuroinflammation

影响因子:10.1

doi:10.1186/s12974-026-03732-3

Cui Dongqing, Liu Shuangwu, Liu Yanxia, Luo Shuqi, Sheng Yurui, Zhang Shuaiyong, Lin Pengfei

NLRP1B is an integrated decoy that subverts Shigella flexneri E3 ligase activity to promote effector-triggered immunity

NLRP1B 是一种整合诱饵蛋白，它能抑制福氏志贺氏菌 E3 连接酶的活性，从而促进效应细胞触发的免疫反应。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2514645123

Chung, Siwon; Hudson, Hannah; Stromberg, Kaitlin A; Sandstrom, Andrew

Redefining Shiga toxin-induced human cell death as NLRP1- and gasdermin E-mediated pyroptosis.

将志贺毒素诱导的人类细胞死亡重新定义为 NLRP1 和 gasdermin E 介导的细胞焦亡。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2510274123

Ricci-Azevedo Rafael, Sarkar Bishajit, Shivcharan Sonia, Hazra Aadrita, Browne Mercy, Carlson Emma K, Chidambaram Udayan, Rathinam Vijay A, Kailasan Vanaja Sivapriya

TKI-mediated inhibition of NLRP1 inflammasome restores erythropoiesis in DBA syndrome.

TKI介导的NLRP1炎症小体抑制可恢复DBA综合征中的红细胞生成。

期刊:EMBO Molecular Medicine

影响因子:8.3

doi:10.1038/s44321-025-00368-3

Lozano-Gil Juan M, RodrÃguez-Ruiz Lola, Palacios Manuel, Peral Jorge, Navarro Susana, Fuster JosÃ© L, BelÃ©ndez Cristina, JÃ©rez AndrÃ©s, Murillo-SanjuÃ¡n Laura, DÃaz-de-Heredia Cristina, LÃ³pez-de-Hontanar GuzmÃ¡n, Zubicaray Josune, Sevilla JuliÃ¡n, Ferrer-MarÃn Francisca, Sepulcre MarÃa P, Cayuela MarÃa L, GarcÃa-Moreno Diana, MartÃnez-LÃ³pez Alicia, Tyrkalska Sylwia D, Mulero Victoriano

LRP1 as a potential diagnostic and immunomodulatory target in endometriosis: evidence from multi-omics and single-cell analyses

LRP1作为子宫内膜异位症潜在的诊断和免疫调节靶点：来自多组学和单细胞分析的证据

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2026.1735221

Xie, Chengmao; Liu, Yong

Retraction: Fexuprazan safeguards the esophagus from hydrochloric acid-induced damage by suppressing NLRP1/Caspase-1/GSDMD pyroptotic pathway

撤稿：非索拉赞通过抑制 NLRP1/Caspase-1/GSDMD 细胞焦亡通路保护食管免受盐酸损伤。

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2026.1809767

Frontiers Editorial Office

Translation of expanded CGG repeats in LRP12 associated oculopharyngodistal myopathy

LRP12相关眼咽远端肌病中CGG重复序列扩增的翻译

期刊:Acta Neuropathologica Communications

影响因子:5.7

doi:10.1186/s40478-026-02272-4

Li, Chengcheng; Daw, Jil A; Pittman, Sara K; Maltby, Connor J; Sakurai, Hidetoshi; Todd, Peter K; Weihl, Conrad C

LRP1

发表日期：2026

文献求助收藏

Role of CTGF-LRP1 in impaired healing of cesarean section incisions.

CTGF-LRP1在剖宫产切口愈合不良中的作用。

Alpinetin Nanoparticles Alleviate Optic Nerve Injury Induced by Acute Glaucoma via LRP1-PPARÎ³ Mediated Regulation of Microglial Lipid Metabolism.

高山黄素纳米颗粒通过 LRP1-PPARγ 介导的小胶质细胞脂质代谢调节来缓解急性青光眼引起的视神经损伤。

The LRP1-SHP2 pathway regulates TRPV1 sensitivity in the peripheral nervous system: Insights from amyloid beta 1-42 modulation.

LRP1-SHP2 通路调节外周神经系统中的 TRPV1 敏感性：来自淀粉样蛋白 β 1-42 调节的启示。

MST1 promotes microglial pyroptosis and neuroinflammation in alzheimer's disease by regulating the novel DPP8/NLRP1/Caspase-1/GSDMD-N axis.

MST1 通过调节新型 DPP8/NLRP1/Caspase-1/GSDMD-N 轴促进阿尔茨海默病中的小胶质细胞焦亡和神经炎症。

NLRP1B is an integrated decoy that subverts Shigella flexneri E3 ligase activity to promote effector-triggered immunity

NLRP1B 是一种整合诱饵蛋白，它能抑制福氏志贺氏菌 E3 连接酶的活性，从而促进效应细胞触发的免疫反应。

Redefining Shiga toxin-induced human cell death as NLRP1- and gasdermin E-mediated pyroptosis.

将志贺毒素诱导的人类细胞死亡重新定义为 NLRP1 和 gasdermin E 介导的细胞焦亡。

TKI-mediated inhibition of NLRP1 inflammasome restores erythropoiesis in DBA syndrome.

TKI介导的NLRP1炎症小体抑制可恢复DBA综合征中的红细胞生成。

LRP1 as a potential diagnostic and immunomodulatory target in endometriosis: evidence from multi-omics and single-cell analyses

LRP1作为子宫内膜异位症潜在的诊断和免疫调节靶点：来自多组学和单细胞分析的证据

Retraction: Fexuprazan safeguards the esophagus from hydrochloric acid-induced damage by suppressing NLRP1/Caspase-1/GSDMD pyroptotic pathway

撤稿：非索拉赞通过抑制 NLRP1/Caspase-1/GSDMD 细胞焦亡通路保护食管免受盐酸损伤。

Translation of expanded CGG repeats in LRP12 associated oculopharyngodistal myopathy

LRP12相关眼咽远端肌病中CGG重复序列扩增的翻译