日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pathogenesis of Noonan Syndrome is Modulated by NOC2L, a Novel Interactor of LZTR1 Leading to Impaired P53 Signalling

Noonan综合征的发病机制受NOC2L调控,NOC2L是LZTR1的一种新型相互作用蛋白,可导致P53信号通路受损。

Chatterjee, Sumana; Ishida, Miho; Bertola, Débora R; Agwu, Juliana Chizo; Gaston-Massuet, Carles; McGuffin, Liam J; Storr, Helen L; Maharaj, Avinaash V

LZTR1 Loss Reduces Vimentin Expression and Motility in Hep3B Hepatocellular Carcinoma Cells.

LZTR1 缺失会降低 Hep3B 肝细胞癌细胞的波形蛋白表达和运动能力。

Yıldız Gökhan, Karabulut Soner, Uzun Umit, Obut Onur, Eldem Vahap, Dinçer Tuba, Toraman Bayram

Central nervous system schwannoma, VGLL-fused (EWSR1::VGLL1 fusion) with neuroblastoma-like cell dense areas in the frontal lobe of a young man with schwannomatosis due to a germline LZTR1 mutation

一名年轻男性,因携带LZTR1基因突变而患有神经鞘瘤病,其额叶可见中枢神经系统神经鞘瘤,肿瘤为VGLL融合型(EWSR1::VGLL1融合),并伴有神经母细胞瘤样细胞密集区域。

Munoz, David G; Das, Sunit; Yoon, Ju-Yoon; Siddaway, Robert; Levine, Adrian; Aldape, Kenneth D

Phosphorylation Protects Oncogenic RAS from LZTR1-Mediated Degradation

磷酸化保护致癌RAS免受LZTR1介导的降解

Zhang, Lin; Bolomsky, Arnold; Al-Odat, Omar S; VanWinkle, Callie; Battle, Aaliyah; Chakraborty, Papiya; Holewinski, Ronald J; Andresson, Thorkell; Meng, Qingcai; Phelan, James D; Muppidi, Jagan; Young, Ryan M

Structural basis for LZTR1 recognition of RAS GTPases for degradation

LZTR1识别RAS GTP酶并进行降解的结构基础

Dharmaiah, Srisathiyanarayanan; Bonsor, Daniel A; Mo, Stephanie P; Fernandez-Cabrera, Alvaro; Chan, Albert H; Messing, Simon; Drew, Matthew; Vega, Martha; Nissley, Dwight V; Esposito, Dominic; Castel, Pau; Simanshu, Dhirendra K

LZTR1 regulates epithelial MHC-I expression via NF-κB1 to modulate CD8+ T cells activation

LZTR1通过NF-κB1调控上皮细胞MHC-I的表达,从而调节CD8+ T细胞的活化。

Rundong Jiang # ,Zhiqin Fang # ,Yutong Wang ,Bo Huang ,Junkun Liu ,Lam C Tsoi ,Rachael Bogle ,Zongbo Zhang ,Yehong Kuang ,Xin Li ,Liang Dong ,Liping Jin ,Johann E Gudjonsson ,Mingzhu Yin ,Xiang Chen

Update on Cancer and Central Nervous System Tumor Surveillance in Pediatric NF2-, SMARCB1-, and LZTR1-Related Schwannomatosis

儿童NF2、SMARCB1和LZTR1相关神经鞘瘤病癌症和中枢神经系统肿瘤监测的最新进展

Perrino, Melissa R; Jongmans, Marjolijn C J; Tomlinson, Gail E; Greer, Mary-Louise C; Scollon, Sarah R; Mitchell, Sarah G; Hansford, Jordan R; Schultz, Kris Ann P; Kohlmann, Wendy K; Kalish, Jennifer M; MacFarland, Suzanne P; Das, Anirban; Maxwell, Kara N; Pfister, Stefan M; Weksberg, Rosanna; Michaeli, Orli; Tabori, Uri; Ney, Gina M; Lupo, Philip J; Brzezinski, Jack J; Stewart, Douglas R; Woodward, Emma R; Kratz, Christian P

LZTR1 is a melanoma oncogene that promotes invasion and suppresses apoptosis

LZTR1是一种黑色素瘤癌基因,它能促进侵袭并抑制细胞凋亡。

Bacchiocchi, Antonella; Mak, Michael; Khan, Zerin Mahzabin; Gong, Xiangyu; Sznol, Mario; Na, Zhenkun; Su, Haomiao; Chan, Lok Hei; Yan, Qin; Zhao, Dejian; Mortlock, Ryland D; Knight, James; Slavoff, Sarah A; Halaban, Ruth

Protein-losing enteropathy and multiple vasculature dysplasia in LZTR1-related Noonan syndrome: A case report and review of literature

LZTR1相关努南综合征中的蛋白丢失性肠病和多发性血管发育不良:病例报告及文献综述

Tian, Qiu-Ju; Zhang, Lu-Jia; Zhang, Qun; Liu, Feng-Chao; Xie, Man; Cai, Jin-Zhen; Rao, Wei

LZTR1: c.1260+1del Variant as a Significant Predictor of Early-Age Breast Cancer Development: Case Report Combined with In Silico Analysis

LZTR1:c.1260+1del变异是早期乳腺癌发生的重要预测因子:病例报告结合计算机模拟分析

Wieleba, Irena; Smoleń, Paulina; Czukiewska, Ewa; Szcześniak, Dominika; Filip, Agata A