日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MCUB Inhibits PRKN-Dependent Mitophagic Degradation of PD-L1 to Promote Immune Evasion in Bladder Cancer.

MCUB抑制PRKN依赖的PD-L1线粒体自噬降解,从而促进膀胱癌的免疫逃逸。

Elevating levels of neuronal MCU in the hippocampus enhances mitochondrial calcium uptake and respiratory efficiency proportional to demand

提高海马体中神经元MCU的水平可增强线粒体钙摄取和呼吸效率,且与需求成正比。

Babalola, O; Boersma, L; Youngberg, C T; Cawley, Mikel L; Montalvo, Ryan N; Wheeler, Mason L; Turner, Lucy L; Pfleger, Jessica; Yan, Zhen; Farris, Shannon

Prognostic significance of calcium signaling-related genes in bladder cancer and the role of ATP2B4 in regulating mitochondrial calcium ion levels via the VDAC1/MCU pathway.

钙信号相关基因在膀胱癌中的预后意义以及 ATP2B4 通过 VDAC1/MCU 通路调节线粒体钙离子水平的作用。

Zhang Lulu, Gong Yu, Chen Jiajun, Li Mengyao, Wang Xiurong, Wang Weihao, Ding Qiannan, Li Yulei

Effects of increasing intranuclear calcium levels via MCU inhibition on mouse and human PSC-derived cardiomyocyte differentiation and maturation

通过抑制MCU增加细胞核内钙水平对小鼠和人PSC衍生心肌细胞分化和成熟的影响

Seo, Hyun Ju; Kim, Ju-Young; Cho, Hyun-Jai; Lee, Joo-Eun; Bang, Sang-Beom; Jeon, Mika; Lee, Hyang-Ae; Shin, Yoo-Jeong; Yang, Han-Mo; Kim, Hyo-Soo

Mitochondrial dysfunction and Ca(2+) dysregulation in human iPSC-derived neurons carrying presenilin-1 mutation arise under stress via an MCU-1-independent mechanism.

携带早老素-1突变的人类iPSC衍生神经元在应激下通过MCU-1非依赖性机制出现线粒体功能障碍和Ca(2+)失调。

Wilson Carlos, Galeano Pablo, Remedi María Mónica, Novack Gisela Vanina, Campanelli Lorenzo, Gastaldi Laura, Miglietta Esteban, Rossi Andres Hugo, Olivar Natividad, Brusco Luis Ignacio, Castaño Eduardo Miguel, Cáceres Alfredo, Morelli Laura

Elevating levels of neuronal MCU in the hippocampus enhances mitochondrial calcium uptake and respiratory efficiency proportional to demand

提高海马体中神经元MCU的水平可增强线粒体钙摄取和呼吸效率,且与需求成正比。

Cawley, Mikel L; Montalvo, Ryan N; Wheeler, Mason L; Turner, Lucy L; Pfleger, Jessica; Yan, Zhen; Farris, Shannon

Targeting Platelet MCU: A Promising Therapeutic Strategy?

靶向血小板MCU:一种有前景的治疗策略?

Jain, Kanika; Hwa, John

Correction to "[Berberine is a Novel Mitochondrial Calcium Uniporter Inhibitor that Disrupts MCU-EMRE Assembly]"

更正“[小檗碱是一种新型线粒体钙单向转运蛋白抑制剂,可破坏MCU-EMRE组装]”

MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology

MCU复合物:探索线粒体生理和病理的新兴靶点和机制

Wang, Jin; Jiang, Jinyong; Hu, Haoliang; Chen, Linxi

Aging aggravated liver ischemia and reperfusion injury by promoting oxidized mtDNA mediated-macrophage pyroptosis through acetylated MCU-dependent calcium uptake.

衰老通过乙酰化 MCU 依赖的钙摄取促进氧化 mtDNA 介导的巨噬细胞焦亡,从而加剧肝脏缺血再灌注损伤。

Wu Xin-Yi, Wang Rui, Zhang Qi, Liu Tao, Liu Jun-Yan, Xu Xue-Song, Gong Jun-Hua