MED12相关文献与解析，生知库 | 链接生命科学的每一步

Impact of MED12 mutation and CDK8 activity on uterine leiomyoma growth and response to gonadotropin-releasing hormone agonist treatment.

MED12 突变和 CDK8 活性对子宫平滑肌瘤生长及促性腺激素释放激素激动剂治疗反应的影响。

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0338485

Tanioka Saki, Asano Ryoko, Ota Yukihide, Nagai Koichi, Takenaka Katsuya, Mizushima Taichi, Miyagi Yohei, Miyagi Etsuko

Molecular pathology of phyllodes tumours of the breast-much more than MED12

乳腺叶状肿瘤的分子病理学——远不止MED12

期刊:Histopathology

影响因子:

doi:10.1111/his.70098

Pang, Jia-Min B; Gorringe, Kylie L; Tan, Puay Hoon; Fox, Stephen B

Vitamin D3 ameliorates R-loop-induced replication stress and chromosomal instability in MED12-mutant uterine fibroids.

维生素 D3 可改善 MED12 突变子宫肌瘤中 R 环诱导的复制压力和染色体不稳定性。

期刊:

影响因子:

doi:10.21203/rs.3.rs-8031602/v1

Muralimanoharan Sribalasubashini, CorachÃ¡n Ana, Khosh Azad, Hathaway Sierra, Karthigayan Susivarshini, Schenken Claire, Stansbury Nicholas, Schenken Robert, Bariani Maria Victoria, Yang Qiwei, Dray Eloise, Adli Mazhar, Ferrero Hortensia, Al-Hendy Ayman, Boyer Thomas G

Functional characterization of the MED12 p.Arg1138Trp variant in females: implications for neural development and disease mechanism

女性MED12 p.Arg1138Trp变异体的功能特征：对神经发育和疾病机制的影响

期刊:Molecular Medicine

影响因子:6.4

doi:10.1186/s10020-025-01365-5

Shaw, Nicole C; Harrison, Saraya; Chen, Kevin; Forbes, Catherine A; Kuzminski, Emma; Hedges, Mitchell; Farley, Kathryn O; Ward, Michelle; Loughman, Lily; Poulton, Cathryn; Baynam, Gareth; Lassmann, Timo; Fear, Vanessa S

Effects of female hormone withdrawal and ulipristal acetate on MED12 mutation positive and negative uterine leiomyomas using a xenograft model

利用异种移植模型研究雌激素撤退和醋酸乌利司他治疗对MED12突变阳性和阴性子宫平滑肌瘤的影响

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-23721-5

Sato, Shun; Sakai, Takahiro; Tamehisa, Tetsuro; Shiroshita, Amon; Takasaki, Hitomi; Kajimura, Takuya; Tamura, Isao; Maekawa, Ryo; Sugino, Norihiro

The MicroRNA miR-454 and the mediator complex component MED12 are regulators of the androgen receptor pathway in prostate cancer

微RNA miR-454和介导复合物组分MED12是前列腺癌中雄激素受体通路的重要调控因子。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-95250-0

Guzman, Juan; Hart, Martin; Weigelt, Katrin; Neumann, Angela; Aigner, Achim; Andolfi, Chiara; Handle, Florian; Rheinheimer, Stefanie; Fischer, Ulrike; Immel, Uta D; Lieb, Verena; Meese, Eckart; Culig, Zoran; Wullich, Bernd; Taubert, Helge; Wach, Sven

Diel cycle of lanthanide-dependent methylotrophy by TMED127/Methylaequorales bacteria in oligotrophic surface seawater

TMED127/甲基水母目细菌在寡营养表层海水中镧系元素依赖性甲基营养的昼夜循环

期刊:Applied and Environmental Microbiology

影响因子:3.7

doi:10.1128/aem.01181-25

Glass, Jennifer B; Warters, Leilani N; Alajlan, Abdulaziz M

Tissue-Specific Genomic Evolution Despite Shared MED12 Mutations in Benign Tumors

尽管良性肿瘤中存在共同的MED12突变，但其基因组进化具有组织特异性

期刊:Journal of Clinical Medicine

影响因子:2.9

doi:10.3390/jcm14207325

Namkung, Jeong; Park, Sang Ho; Hwang, Ayoung; Seo, Hae; Park, Jooyoung; Lee, Moonyoung; Kim, Hyunkyung; Choi, Jungmin; Song, Jae Yen

Antenatal Pulmonary Hypoplasia Expands the Variety of Phenotypes Associated With MED12-Related Disorders

产前肺发育不全扩大了与MED12相关疾病相关的表型种类

期刊:Prenatal Diagnosis

影响因子:2.7

doi:10.1002/pd.6881

Ramachandran, Vijaya; Chandler, Natalie J; Gibbs, Alexander; Whitby, Elspeth; Braham, Ruth; Christopher, Joseph; Mehta, Sarju G

MED12 Dictates Epithelial Ovarian Cancer Cell Ferroptosis Sensitivity via YAP-TEAD1 Signaling

MED12通过YAP-TEAD1信号通路调控上皮性卵巢癌细胞对铁死亡的敏感性

Impact of MED12 mutation and CDK8 activity on uterine leiomyoma growth and response to gonadotropin-releasing hormone agonist treatment.

MED12 突变和 CDK8 活性对子宫平滑肌瘤生长及促性腺激素释放激素激动剂治疗反应的影响。

Molecular pathology of phyllodes tumours of the breast-much more than MED12

乳腺叶状肿瘤的分子病理学——远不止MED12

Vitamin D3 ameliorates R-loop-induced replication stress and chromosomal instability in MED12-mutant uterine fibroids.

维生素 D3 可改善 MED12 突变子宫肌瘤中 R 环诱导的复制压力和染色体不稳定性。

Functional characterization of the MED12 p.Arg1138Trp variant in females: implications for neural development and disease mechanism

女性MED12 p.Arg1138Trp变异体的功能特征：对神经发育和疾病机制的影响

Effects of female hormone withdrawal and ulipristal acetate on MED12 mutation positive and negative uterine leiomyomas using a xenograft model

利用异种移植模型研究雌激素撤退和醋酸乌利司他治疗对MED12突变阳性和阴性子宫平滑肌瘤的影响

The MicroRNA miR-454 and the mediator complex component MED12 are regulators of the androgen receptor pathway in prostate cancer

微RNA miR-454和介导复合物组分MED12是前列腺癌中雄激素受体通路的重要调控因子。

Diel cycle of lanthanide-dependent methylotrophy by TMED127/Methylaequorales bacteria in oligotrophic surface seawater

TMED127/甲基水母目细菌在寡营养表层海水中镧系元素依赖性甲基营养的昼夜循环

Tissue-Specific Genomic Evolution Despite Shared MED12 Mutations in Benign Tumors

尽管良性肿瘤中存在共同的MED12突变，但其基因组进化具有组织特异性

Antenatal Pulmonary Hypoplasia Expands the Variety of Phenotypes Associated With MED12-Related Disorders

产前肺发育不全扩大了与MED12相关疾病相关的表型种类