METTL16相关文献与解析，生知库 | 链接生命科学的每一步

Chen, Jinsuo; Liu, Huan; Zhang, Yong; Gu, Junfei; Wu, Xiaoli; Xuan, Fan; Qu, Changbao; Sun, Hao; Yue, Nanxi; Yang, Chenxiao; Zhao, Hongye; Yang, Wenzeng; Yang, Zhan

METTL16

CDK1

肿瘤

Loss of UFL1 confers enzalutamide resistance of prostate tumors by regulating METTL16-mediated m6A modification of EEF1A1 mRNA.

UFL1 的缺失通过调节 METTL16 介导的 EEF1A1 mRNA 的 m6A 修饰，使前列腺肿瘤对恩扎卢胺产生耐药性。

期刊:International Journal of Biological Sciences

影响因子:10

doi:10.7150/ijbs.124214

Wu Xu, Gao Hui, Zhuang Qianfeng, Li Feng, Feng Xingliang, Shao Naiyuan, Zhang Wei, Zhang Yuyang, Zhang Xiansheng

YTHDC1 recognizes METTL16-dependent m(6)A on caRNAs and coordinates cotranscriptional splicing

YTHDC1识别caRNA上METTL16依赖的m(6)A并协调共转录剪接

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2524579123

Zhang, Zhong; Yin, Qi; Lin, Weimin; Li, Qiwen; Sheng, Rui; Jiang, Shuang; Lei, Kexin; Liu, Linfeng; Zhang, Lanxin; Qian, Chunlin; Wen, Junru; Wang, Zirui; Chen, Chong; Yuan, Quan

METTL16 promotes MASLD progression through the regulation of lipid synthesis and immune response

METTL16 通过调节脂质合成和免疫反应促进 MASLD 的进展

期刊:Biology Direct

影响因子:4.9

doi:10.1186/s13062-026-00760-0

Li, Guixin; Wang, Long; Zhang, Li; Guo, Jinghui; Sun, Qun

METTL16 Inhibits Lens Epithelial Cells Function in Diabetic Cataract via m6A-Modified DKK1-Mediated Wnt/Î²-Catenin Signaling.

METTL16 通过 m6A 修饰的 DKK1 介导的 Wnt/β-catenin 信号通路抑制糖尿病性白内障晶状体上皮细胞的功能。

期刊:Investigative Ophthalmology & Visual Science

影响因子:4.7

doi:10.1167/iovs.67.1.1

Zhang Bei, Sun Yahui, Jiang Xiaohui, Hu Zhixuan, Wang Xue, Zhao Yun-E

METTL16-m6A-PGC-1α axis contributes to exercise-induced mitochondrial adaptations in skeletal muscle of high-fat diet-fed insulin-resistant mice

METTL16-m6A-PGC-1α轴参与高脂饮食喂养的胰岛素抵抗小鼠骨骼肌中运动诱导的线粒体适应性改变

期刊:BMC Biology

影响因子:4.4

doi:10.1186/s12915-026-02519-5.

Cong Chen #,Cai Jiang #,Qing Xiang #,Yue Hu,Huijuan Wu,Chunxiu Huang,Huanghao Zhou,Ying Xu,Meijin Hou,Weilin Liu,Xiao Han

The methyltransferase METTL16 in digestive system cancers: functions and mechanisms

消化系统癌症中的甲基转移酶METTL16：功能和机制

期刊:Frontiers in Oncology

影响因子:3.3

doi:10.3389/fonc.2026.1744928

Li, Jia; Bao, Yueyuan; Yao, Fei; Wu, Qingming

Novel N(6)-methyladenosine (m(6)A) writer METTL16 promotes the cervical cancer tumorigenesis by targeting FTH1-dependent ferroptosis

新型N(6)-甲基腺苷(m(6)A)写入酶METTL16通过靶向FTH1依赖性铁死亡促进宫颈癌的肿瘤发生

期刊:Discover Oncology

影响因子:2.9

doi:10.1007/s12672-026-04403-8

Huang, Zhisheng; Luo, Youzhen; Gao, Qiaoling; Wang, Lulu; Li, Caihong

METTL16 Promotes Cerebral Ischemia-Reperfusion Injury via m(6)A-Dependent Upregulation of TIPARP.

METTL16 通过 m(6)A 依赖性上调 TIPARP 促进脑缺血再灌注损伤。

期刊:International Journal of General Medicine

影响因子:2

doi:10.2147/IJGM.S561723

Xiang Meiling, Han Jiemi, Ye Zai, Chen Bimeng, Wang Hongbo

METTL16 antagonizes astaxanthin-induced ferroptosis in colorectal cancer cells

METTL16拮抗虾青素诱导的结直肠癌细胞铁死亡

期刊:Translational Cancer Research

影响因子:1.7

doi:10.21037/tcr-2025-2002

Zeng, Xianzhen; Wang, Xinyu; Wang, Jiao; Zheng, Rui; Zhang, Yingjie; Li, Tonggang; Ma, Jia; Pan, Xueshan

CDK13 drives clear cell renal carcinoma through METTL16-mediated m(6)A modification of ACLY mRNA

CDK13 通过 METTL16 介导的 ACLY mRNA 的 m(6)A 修饰驱动透明细胞肾细胞癌的发生

Loss of UFL1 confers enzalutamide resistance of prostate tumors by regulating METTL16-mediated m6A modification of EEF1A1 mRNA.

UFL1 的缺失通过调节 METTL16 介导的 EEF1A1 mRNA 的 m6A 修饰，使前列腺肿瘤对恩扎卢胺产生耐药性。

YTHDC1 recognizes METTL16-dependent m(6)A on caRNAs and coordinates cotranscriptional splicing

YTHDC1识别caRNA上METTL16依赖的m(6)A并协调共转录剪接

METTL16 promotes MASLD progression through the regulation of lipid synthesis and immune response

METTL16 通过调节脂质合成和免疫反应促进 MASLD 的进展

METTL16 Inhibits Lens Epithelial Cells Function in Diabetic Cataract via m6A-Modified DKK1-Mediated Wnt/Î²-Catenin Signaling.

METTL16 通过 m6A 修饰的 DKK1 介导的 Wnt/β-catenin 信号通路抑制糖尿病性白内障晶状体上皮细胞的功能。

METTL16-m6A-PGC-1α axis contributes to exercise-induced mitochondrial adaptations in skeletal muscle of high-fat diet-fed insulin-resistant mice

METTL16-m6A-PGC-1α轴参与高脂饮食喂养的胰岛素抵抗小鼠骨骼肌中运动诱导的线粒体适应性改变

The methyltransferase METTL16 in digestive system cancers: functions and mechanisms

消化系统癌症中的甲基转移酶METTL16：功能和机制

Novel N(6)-methyladenosine (m(6)A) writer METTL16 promotes the cervical cancer tumorigenesis by targeting FTH1-dependent ferroptosis

新型N(6)-甲基腺苷(m(6)A)写入酶METTL16通过靶向FTH1依赖性铁死亡促进宫颈癌的肿瘤发生

METTL16 Promotes Cerebral Ischemia-Reperfusion Injury via m(6)A-Dependent Upregulation of TIPARP.

METTL16 通过 m(6)A 依赖性上调 TIPARP 促进脑缺血再灌注损伤。

METTL16 antagonizes astaxanthin-induced ferroptosis in colorectal cancer cells

METTL16拮抗虾青素诱导的结直肠癌细胞铁死亡