A novel peptide MIB1-223aa encoded by exosomal circMIB1 from cancer-associated fibroblasts drives triple-negative breast cancer metastasis and stemness via stabilizing MIB1 to activate Notch signaling
来自癌症相关成纤维细胞的外泌体 circMIB1 编码的一种新型肽 MIB1-223aa，通过稳定 MIB1 激活 Notch 信号通路，驱动三阴性乳腺癌的转移和干性。
期刊:Journal of Advanced Research
影响因子:13
doi:10.1016/j.jare.2025.06.023
Ye, Fangzhou; Liang, Yiran; Wang, Jianing; Song, Jiayin; Jin, Yuhan; Wang, Lei; Luo, Dan; Li, Xiaoyan; Li, Yaming; Han, Dianwen; Chen, Tong; Chen, Bing; Zhao, Wenjing; Wang, Lijuan; Yang, Qifeng
外泌体
成纤维细胞
肿瘤
肿瘤免疫
Notch
信号转导
乳腺癌
MIB1
细胞生物学
