MRP1相关文献与解析，生知库 | 链接生命科学的每一步

Shi, Zixin; Qin, Ziniu; Chen, Chuantao; Yang, Xiaolin; Hu, Yunhan; Meng, Xiaohui; Cao, Yuxiang; Tao, Xiang; Zhang, Zhijian; Xie, Tiancheng; Wei, Huijun; Wu, Zhihao

肺癌

肿瘤

肿瘤免疫

Investigating of harmane, harmine, and norharman as inhibitors of MDR1 and MRP1 to overcome chemotherapy resistance in cancer cells

研究哈尔满、哈尔明和去甲哈尔满作为 MDR1 和 MRP1 抑制剂，以克服癌细胞的化疗耐药性

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-28479-4

Abdi, Neda; Banitalebi, Arezou; Heidari, Razieh; Zahedian, Sorur; Mirzaei, Seyed Abbas; Elahian, Fatemeh

Combination effects of Pistachio hull and carfilzomib on NF-κB p65, MDR1, MRP1, and Caspase3 gene expression in breast cancer cell line

开心果壳和卡非佐米联合作用对乳腺癌细胞系中 NF-κB p65、MDR1、MRP1 和 Caspase3 基因表达的影响

期刊:BMC Complementary Medicine and Therapies

影响因子:3.4

doi:10.1186/s12906-024-04716-7

Mirzaei, Zahra; Zarei, Sadegh; Sayadi, Ahmadreza; Hosseiniara, Reza; Karimabad, Mojgan Noroozi; Mahmoodi, Mehdi

Re-sensitization of cancer multidrug resistance through P-gp, MRP1 and BCRP modulation: advances in terpenoids based cancer therapy

通过调节 P-gp、MRP1 和 BCRP 重新激活癌症多药耐药性：萜类化合物癌症治疗的进展

期刊:Discover Oncology

影响因子:2.9

doi:10.1007/s12672-025-03593-x

Pandey, Pratibha; Singh, Ajay; Lakhanpal, Sorabh; Rekha, M; Mangaraj, Swayamsidha; Verma, Meenakshi; Upadhye, Vijay Jagdish; Khan, Fahad

Expression and interaction of RNA binding protein HuR with multidrug transporters (P-GP, MRP1, and ABCG2) in chemoresistant breast and colorectal cancer cells.

RNA结合蛋白HuR与多药转运蛋白（P-GP、MRP1和ABCG2）在耐药乳腺癌和结直肠癌细胞中的表达和相互作用。

期刊:Journal of Genetic Engineering and Biotechnology

影响因子:2.8

doi:10.1016/j.jgeb.2025.100594

Nath Sudipta Deb, Akash Md Mahmudul Hasan, Tanim Md Tamzid Hossain, Akhteruzzaman Sharif, Mostafa Mohammad Golam, Sajib Abu Ashfaqur

A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation

大环肽抑制剂将MRP1捕获在一种催化活性丧失的构象中。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2220012120

Pietz, Harlan L; Abbas, Ata; Johnson, Zachary Lee; Oldham, Michael L; Suga, Hiroaki; Chen, Jue

MRP1

发表日期：2023

文献求助收藏

[Retracted] MicroRNA‑9 limits hepatic fibrosis by suppressing the activation and proliferation of hepatic stellate cells by directly targeting MRP1/ABCC1

[已撤稿] MicroRNA-9 通过直接靶向 MRP1/ABCC1 抑制肝星状细胞的活化和增殖，从而限制肝纤维化

期刊:Oncology Reports

影响因子:3.9

doi:10.3892/or.2023.8590

Sun, Jie; Zhang, Huanying; Li, Liying; Yu, Lianfeng; Fu, Lifang

Phloridzin Docosahexaenoate Inhibits Spheroid Formation by Breast Cancer Stem Cells and Exhibits Cytotoxic Effects against Paclitaxel-Resistant Triple Negative Breast Cancer Cells

根皮苷二十二碳六烯酸酯可抑制乳腺癌干细胞的球体形成，并对紫杉醇耐药的三阴性乳腺癌细胞表现出细胞毒性作用

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms241914577

Wasundara Fernando, Rikki F Clark, H P Vasantha Rupasinghe, David W Hoskin, Melanie R Power Coombs

Sorafenib Chemosensitization by Caryophyllane Sesquiterpenes in Liver, Biliary, and Pancreatic Cancer Cells: The Role of STAT3/ABC Transporter Axis

石竹烷倍半萜对肝、胆和胰腺癌细胞索拉非尼化学增敏作用：STAT3/ABC 转运蛋白轴的作用

期刊:Pharmaceutics

影响因子:4.9

doi:10.3390/pharmaceutics14061264

Silvia Di Giacomo, Marco Gullì, Roberta Facchinetti, Marco Minacori, Romina Mancinelli, Ester Percaccio, Caterina Scuderi, Margherita Eufemi, Antonella Di Sotto

Use of PET Imaging to Assess the Efficacy of Thiethylperazine to Stimulate Cerebral MRP1 Transport Activity in Wild-Type and APP/PS1-21 Mice

利用PET成像评估噻乙哌嗪刺激野生型和APP/PS1-21小鼠脑内MRP1转运活性的功效

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms23126514

Wölfl-Duchek, Michael; Mairinger, Severin; Hernández-Lozano, Irene; Filip, Thomas; Zoufal, Viktoria; Löbsch, Mathilde; Stanek, Johann; Kuntner, Claudia; Wanek, Thomas; Bauer, Martin; Pahnke, Jens; Langer, Oliver

BMAL1 Drives Cisplatin Resistance in Non-Small Cell Lung Cancer Via Lactate-MRP1 Signaling Pathway

BMAL1通过乳酸-MRP1信号通路驱动非小细胞肺癌的顺铂耐药性

Investigating of harmane, harmine, and norharman as inhibitors of MDR1 and MRP1 to overcome chemotherapy resistance in cancer cells

研究哈尔满、哈尔明和去甲哈尔满作为 MDR1 和 MRP1 抑制剂，以克服癌细胞的化疗耐药性

Combination effects of Pistachio hull and carfilzomib on NF-κB p65, MDR1, MRP1, and Caspase3 gene expression in breast cancer cell line

开心果壳和卡非佐米联合作用对乳腺癌细胞系中 NF-κB p65、MDR1、MRP1 和 Caspase3 基因表达的影响

Re-sensitization of cancer multidrug resistance through P-gp, MRP1 and BCRP modulation: advances in terpenoids based cancer therapy

通过调节 P-gp、MRP1 和 BCRP 重新激活癌症多药耐药性：萜类化合物癌症治疗的进展

Expression and interaction of RNA binding protein HuR with multidrug transporters (P-GP, MRP1, and ABCG2) in chemoresistant breast and colorectal cancer cells.

RNA结合蛋白HuR与多药转运蛋白（P-GP、MRP1和ABCG2）在耐药乳腺癌和结直肠癌细胞中的表达和相互作用。

A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation

大环肽抑制剂将MRP1捕获在一种催化活性丧失的构象中。

[Retracted] MicroRNA‑9 limits hepatic fibrosis by suppressing the activation and proliferation of hepatic stellate cells by directly targeting MRP1/ABCC1

[已撤稿] MicroRNA-9 通过直接靶向 MRP1/ABCC1 抑制肝星状细胞的活化和增殖，从而限制肝纤维化

Phloridzin Docosahexaenoate Inhibits Spheroid Formation by Breast Cancer Stem Cells and Exhibits Cytotoxic Effects against Paclitaxel-Resistant Triple Negative Breast Cancer Cells

根皮苷二十二碳六烯酸酯可抑制乳腺癌干细胞的球体形成，并对紫杉醇耐药的三阴性乳腺癌细胞表现出细胞毒性作用

Sorafenib Chemosensitization by Caryophyllane Sesquiterpenes in Liver, Biliary, and Pancreatic Cancer Cells: The Role of STAT3/ABC Transporter Axis

石竹烷倍半萜对肝、胆和胰腺癌细胞索拉非尼化学增敏作用：STAT3/ABC 转运蛋白轴的作用

Use of PET Imaging to Assess the Efficacy of Thiethylperazine to Stimulate Cerebral MRP1 Transport Activity in Wild-Type and APP/PS1-21 Mice

利用PET成像评估噻乙哌嗪刺激野生型和APP/PS1-21小鼠脑内MRP1转运活性的功效