MYD88相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Ningxiang pig-derived Enterococcus hirae protects against E. coli-induced gut dysbiosis and inflammation via acetate/propionate-MyD88-NF-ÎºB axis in piglets.

宁乡猪源粪肠球菌通过乙酸/丙酸-MyD88-NF-β轴保护仔猪免受大肠杆菌引起的肠道菌群失调和炎症。

期刊:Microbiome

影响因子:12.7

doi:10.1186/s40168-025-02310-8

Zhang Longlin, Wu Zichen, Shen Haibo, Meng Yunlong, Li Hongkun, Cai Rong, Tang Dalin, Kang Meng, Yin Yulong, Tan Bie, Wang Jing

Immunology/Inflammation

发表日期：2026

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Quantitative MYD88L265P and CXCR4S338X analysis to assess clinical trial performance in Waldenstrom macroglobulinemia

定量 MYD88L265P 和 CXCR4S338X 分析用于评估华氏巨球蛋白血症临床试验的性能

期刊:Blood Advances

影响因子:7.1

doi:10.1182/bloodadvances.2025018605

Tsakmaklis, Nickolas; Hunter, Zachary R; Liu, Xia; Kofides, Amanda; Liu, Shirong; Guerrera, Maria Luisa; Guijosa, Alberto; Sun, Hao; Hatcher, John M; Peachey, Abigail; Patterson, Christopher J; Meid, Kirsten; Gustine, Joshua; Branagan, Andrew R; Sarosiek, Shayna R; Castillo, Jorge J; Treon, Steven P

发表日期：2026

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Three Polyphenolic Compounds from Inonotus obliquus: Antioxidant Activity, Xanthine Oxidase Inhibition, and Regulatory Effects on MyD88/TLR4/NF-ÎºB Pathway in MSU-Induced RAW 264.7 Macrophages.

来自白桦茸的三种多酚化合物：抗氧化活性、黄嘌呤氧化酶抑制以及对 MSU 诱导的 RAW 264.7 巨噬细胞中 MyD88/TLR4/NF-κB 通路的调节作用。

期刊:Antioxidants

影响因子:6.6

doi:10.3390/antiox15020267

Shu Yuting, Chen Jiahui, Pang Shuyue, Liu Hongfei, Bai Helong, Chen Lina, Wang Jing, Meng Fanlei

细胞生物学

发表日期：2026

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Small B-cell lymphoma highly suspicious for splenic marginal zone lymphoma with MYD88 L265P mutation and MYC copy-number gain presenting as severe autoimmune hemolytic anemia: a case report with literature review

一例高度疑似脾边缘区淋巴瘤的小B细胞淋巴瘤，伴MYD88 L265P突变和MYC拷贝数增加，表现为严重的自身免疫性溶血性贫血：病例报告及文献复习

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2026.1767267

Liu, Xiaoyan; Zhang, Guoyang; Ma, Liping

细胞生物学

免疫/内分泌

发表日期：2026

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The novel IDO-1 inhibitor 3-047 combined with icaritin ameliorates neuroinflammation and diabetes-associated cognitive dysfunction with suppression of TLR4/MyD88/NF-ÎºB signaling.

新型 IDO-1 抑制剂 3-047 与淫羊藿苷联合使用，可通过抑制 TLR4/MyD88/NF-κB 信号传导来改善神经炎症和糖尿病相关的认知功能障碍。

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2026.1704307

Mo Tingmei, Zhuang Xia, Zhao Wenxue, Wang Baohua, Wang Yuting, Ji Wenjie, Liu Dongguang, Zhang Guimin, Yao Ru, Xu Yan, Yao Jingchun

Immunology/Inflammation

发表日期：2026

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Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axis

猪源脱细胞神经基质水凝胶通过抑制TLR4/MyD88/NF-κB轴减轻周围神经损伤后的神经炎症。

期刊:Neural Regeneration Research

影响因子:5.9

doi:10.4103/NRR.NRR-D-24-00302

Rui Li ，Jianquan Liu ，Liuxun Li ，Guotian Luo ，Xinrong Yuan ，Shichao Shen ，Yongpeng Shi ，Jianlong Wu ，Bin Yan ，Lei Yang

细胞生物学

发表日期：2026

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Obacunone Promotes Functional Recovery After Spinal Cord Injury by Attenuating Neuroinflammation by Targeting the TLR4/MyD88/p38 MAPK Pathway.

Obacunone 通过靶向 TLR4/MyD88/p38 MAPK 通路减轻神经炎症，从而促进脊髓损伤后的功能恢复。

期刊:Drug Design Development and Therapy

影响因子:5.1

doi:10.2147/DDDT.S577707

Kuang Wenhao, Zhang Mi, Zhang Jiaqi, Huang Haoran, Chen Qifan, Yu Cheng, Peng Birong, Sun Wei, Lin Jiezhao, Cheng Junjie, Zhu Lixin

Immunology/Inflammation

发表日期：2026

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HSP60 Mediates NLRP3 Inflammasome-Dependent Microglial Pyroptosis Via the TLR4/MyD88/NF-ÎºB Signaling Axis After Subarachnoid Hemorrhage.

蛛网膜下腔出血后，HSP60 通过 TLR4/MyD88/NF-κB 信号轴介导 NLRP3 炎症小体依赖性小胶质细胞焦亡。

期刊:Inflammation

doi:10.1007/s10753-025-02442-x

Hu Zheng-Qing, Ma Ruijie, Zhang Hang, Miao Jiahao, Sun Jia-Qing, Yuan Jinlong, Liu Jiaqiang, Zhang Zihuan, Xia Dayong

细胞生物学

发表日期：2026

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Central Irisin Administration Attenuates Hypothalamic TLR4/MyD88-Mediated Neuroinflammatory Signaling in Diet-Induced Obese Mice.

中枢注射鸢尾素可减弱饮食诱导肥胖小鼠下丘脑 TLR4/MyD88 介导的神经炎症信号传导。

期刊:Molecular Neurobiology

影响因子:4.3

doi:10.1007/s12035-026-05729-8

Bem Kelly Cristina Pereira, Talpo Tassiana Cristina, da Silva Nogueira Guilherme Augusto, Zanesco Ariane Maria, Sidarta-Oliveira Davi, da Silva Junior Joel Alves, Boschero Antonio Carlos, Velloso Licio Augusto, de Lima Barbosa Helena Cristina

发表日期：2026

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Repurposing pacritinib to target MYD88-mutated Waldenström macroglobulinaemia

将帕克替尼用于治疗MYD88突变型华氏巨球蛋白血症

期刊:British Journal of Haematology

影响因子:3.8

doi:10.1111/bjh.70254

Liu, Shirong; Kofides, Amanda; Liu, Xia; Hatcher, John M; Sun, Hao; Tsakmaklis, Nicholas; Guijosa, Alberto; Guerrera, Maria L; Pizzarella, Dominic; Peachey, Abigail L; Patterson, Christopher J; Hunter, Zachary R; Meid, Kirsten; Castillo, Jorge J; Sarosiek, Shayna R; Treon, Steven P

发表日期：2026

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