NDRG1相关文献与解析，生知库 | 链接生命科学的每一步

Correction to: Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells

更正：Dp44mT 通过转移抑制因子 NDRG1 靶向正常前列腺上皮细胞和前列腺癌细胞中的 AKT、TGF-β 和 ERK 通路。

期刊:British Journal of Cancer

影响因子:6.8

doi:10.1038/s41416-026-03353-w

Dixon, K M; Lui, G Y L; Kovacevic, Z; Zhang, D; Yao, M; Chen, Z; Dong, Q; Assinder, S J; Richardson, D R

Phosphorylation disrupts the interaction between the intrinsically disordered region of the oncogenic NDRG1 and lipid vesicles

磷酸化会破坏致癌NDRG1固有无序区与脂质囊泡之间的相互作用。

期刊:Protein Science

影响因子:5.2

doi:10.1002/pro.70510

Carosella, Noemi; Pastorello, Chiara; Waeytens, Jehan; Beniamino, Ylenia; Roncassaglia, Valentina; Serra, Lucrezia; Raussens, Vincent; Mileo, Elisabetta; Ciurli, Stefano; Zambelli, Barbara

Interaction of NDRG1 and TGM2 modulates DNA replication and repair

NDRG1和TGM2的相互作用调节DNA复制和修复

期刊:Molecular Cancer Research

影响因子:4.7

doi:10.1158/1541-7786.MCR-25-0743

Doh, Hanna M; Kozlova, Nina; Cruz, Kayla A; Muranen, Taru

NDRG1

发表日期：2026

文献求助收藏

IRF6 induces endothelial dysfunction through the transcriptional activation of NDRG1 and aggravates low shear stress-mediated atherosclerosis.

IRF6 通过 NDRG1 的转录激活诱导内皮功能障碍，并加剧低剪切应力介导的动脉粥样硬化。

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2026.115127

Chen Yong, Zhang Yanchao, Rui Shen, Dong Bo, Xu Xiangshan, Jin Yuanzhe

WISP1 is the stromal-secreting oncoprotein via paracrine downregulation of NDRG1, KAI1, and Maspin in human bladder cancer cells.

WISP1 是一种基质分泌癌蛋白，它通过旁分泌下调 NDRG1、KAI1 和 Maspin 来抑制人类膀胱癌细胞的生长。

期刊:Translational Oncology

影响因子:4.1

doi:10.1016/j.tranon.2026.102680

Chen Syue-Ting, Chang Kang-Shuo, Hou Chen-Pang, Lin Wei-Yin, Hsu Shu-Yuan, Sung Hsin-Ching, Feng Tsui-Hsia, Lin Yu-Hsiang, Juang Horng-Heng

NDRG1 aggravates Sepsis-Induced acute lung injury via PKM2-dependent activation of STAT3 and NF-κB signaling

NDRG1通过PKM2依赖性激活STAT3和NF-κB信号通路加重脓毒症引起的急性肺损伤

期刊:BMC Immunology

影响因子:2.7

doi:10.1186/s12865-026-00812-0

Yang, Yifan; Zhang, Dian; Xu, Zhangling; Wang, Chao; Wu, Ruo; Ma, Senlin; Yuan, Yinuo; Sun, Yuxin; Qian, Junwei; Jiang, Xiaofei; Ma, Chunlai; Chen, Mingquan

NDRG1 enhances the sensitivity to Cetuximab by promoting Stat1 ubiquitylation in colorectal cancer

NDRG1通过促进结直肠癌中Stat1的泛素化来增强对西妥昔单抗的敏感性

期刊:Journal of Advanced Research

影响因子:13

doi:10.1016/j.jare.2024.07.035

Yang, Guang; Ding, Chengsheng; Yang, Xiao; Jiang, Jiang; He, Shiyuan; Shao, Yanfei; Zhang, Enkui; Fan, Xiaodong; Zhou, Xueliang; Huang, Ling; Xinyu Zhang, Cindy; Sun, Jing; Wang, Yu; Zang, Lu; Zheng, Minhua; Ma, Junjun

NDRG1 as a sensor and mediator of endothelial stress: from homeostasis to inflammation and cardiovascular disease

NDRG1作为内皮应激的传感器和介质：从体内平衡到炎症和心血管疾病

期刊:Cellular and Molecular Life Sciences

影响因子:6.2

doi:10.1007/s00018-025-05894-4

Etuze, Tamara; Repesse, Yohann; Vivien, Denis; Dubois, Fatemeh

Insight into the Regulation of NDRG1 Expression

深入了解NDRG1表达调控机制

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26083582

Saponaro, Concetta; Gammaldi, Nicola; Cavallo, Viviana; Ramírez-Morales, Maria Antonieta; Zito, Francesco Alfredo; Sonnessa, Margherita; Vari, Francesco; Serra, Ilaria; De Summa, Simona; Giudetti, Anna Maria; Trerotola, Marco; Vergara, Daniele

Magnolin overcomes EGFR TKI resistance in NSCLC by modulation of NDRG1-NRG2-HECW1 pathway

Magnolin通过调节NDRG1-NRG2-HECW1通路克服非小细胞肺癌中的EGFR TKI耐药性

Correction to: Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells

更正：Dp44mT 通过转移抑制因子 NDRG1 靶向正常前列腺上皮细胞和前列腺癌细胞中的 AKT、TGF-β 和 ERK 通路。

Phosphorylation disrupts the interaction between the intrinsically disordered region of the oncogenic NDRG1 and lipid vesicles

磷酸化会破坏致癌NDRG1固有无序区与脂质囊泡之间的相互作用。

Interaction of NDRG1 and TGM2 modulates DNA replication and repair

NDRG1和TGM2的相互作用调节DNA复制和修复

IRF6 induces endothelial dysfunction through the transcriptional activation of NDRG1 and aggravates low shear stress-mediated atherosclerosis.

IRF6 通过 NDRG1 的转录激活诱导内皮功能障碍，并加剧低剪切应力介导的动脉粥样硬化。

WISP1 is the stromal-secreting oncoprotein via paracrine downregulation of NDRG1, KAI1, and Maspin in human bladder cancer cells.

WISP1 是一种基质分泌癌蛋白，它通过旁分泌下调 NDRG1、KAI1 和 Maspin 来抑制人类膀胱癌细胞的生长。

NDRG1 aggravates Sepsis-Induced acute lung injury via PKM2-dependent activation of STAT3 and NF-κB signaling

NDRG1通过PKM2依赖性激活STAT3和NF-κB信号通路加重脓毒症引起的急性肺损伤

NDRG1 enhances the sensitivity to Cetuximab by promoting Stat1 ubiquitylation in colorectal cancer

NDRG1通过促进结直肠癌中Stat1的泛素化来增强对西妥昔单抗的敏感性

NDRG1 as a sensor and mediator of endothelial stress: from homeostasis to inflammation and cardiovascular disease

NDRG1作为内皮应激的传感器和介质：从体内平衡到炎症和心血管疾病

Insight into the Regulation of NDRG1 Expression

深入了解NDRG1表达调控机制