日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A conserved salt bridge network stabilizes the hepatic organic anion transporters OATP1B1 and OATP1B3

保守的盐桥网络稳定了肝脏有机阴离子转运蛋白OATP1B1和OATP1B3。

Barber, Drew; Naughton, Fiona; van Hilten, Niek; Grabe, Michael; Paz, Aviv

Population Pharmacokinetic Modeling of Glycochenodeoxycholic Acid 3-O-Sulfate (GCDCA-S) as Endogenous Biomarker of OATP1B3 and OAT3 Transporters

以甘氨胆酸3-O-硫酸酯(GCDCA-S)作为OATP1B3和OAT3转运蛋白的内源性生物标志物进行群体药代动力学建模

Ujihira, Yuki; Georgiev, Viktor; Ogungbenro, Kayode; Galetin, Aleksandra

Association Study of OATP1B3 Polymorphisms on Hepatic Uptake and Drug-Drug Interaction In Vitro

OATP1B3多态性与肝脏摄取和体外药物相互作用的关联研究

Yang, Ziwei; Chen, Yuewen; Tian, Guanfang; Wang, Xiaoliang; Wang, Ze

Integrative Multi-Omics and Functional Validation Reveal the Role of the TACE Refractoriness-Associated Gene ATP1B3 in Hepatocellular Carcinoma.

整合多组学和功能验证揭示了 TACE 耐药相关基因 ATP1B3 在肝细胞癌中的作用。

ATP1B3 may promote glioma proliferation and migration through MAPK/NF-KB signaling pathway

ATP1B3可能通过MAPK/NF-κB信号通路促进胶质瘤的增殖和迁移。

Yan, Qikang; Sun, Quan; Feng, Yan; Hu, Qingyun; Zhu, Jinling

G45 and V386 in Transmembrane Domains 1 and 8 Are Critical for the Activation of OATP1B3-Mediated E17βG Uptake by Clotrimazole

跨膜结构域 1 和 8 中的 G45 和 V386 对克霉唑激活 OATP1B3 介导的 E17βG 摄取至关重要

Wanjun Han, Zheyue Bo, Ting Liang, Han Liu, Lanjing Li, Zhening Guo, Ru Huan, Bruno Hagenbuch, Chunshan Gui

Elucidating nonlinear pharmacokinetics of telmisartan: Integration of target-mediated drug disposition and OATP1B3-mediated hepatic uptake in a physiologically based model

阐明替米沙坦的非线性药代动力学:在生理模型中整合靶标介导的药物分布和 OATP1B3 介导的肝脏摄取

Toshiaki Tsuchitani, Atsuko Tomaru, Yasunori Aoki, Naoki Ishiguro, Yasuhiro Tsuda, Yuichi Sugiyama

Transcriptional Regulation of Liver-Type OATP1B3 (Lt-OATP1B3) and Cancer-Type OATP1B3 (Ct-OATP1B3) Studied in Hepatocyte-Derived and Colon Cancer-Derived Cell Lines

在肝细胞来源和结肠癌细胞来源的细胞系中研究肝型 OATP1B3 (Lt-OATP1B3) 和癌型 OATP1B3 (Ct-OATP1B3) 的转录调控

Haberkorn, Bastian; Löwen, Dennis; Meier, Lukas; Fromm, Martin F; König, Jörg

Differential Preincubation Effects of Nicardipine on OATP1B1- and OATP1B3-Mediated Transport in the Presence and Absence of Protein: Implications in Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions

尼卡地平在有无蛋白质存在下对OATP1B1和OATP1B3介导的转运的差异性预孵育效应:对评估OATP1B1和OATP1B3介导的药物相互作用的意义

Kayesh, Ruhul; Tambe, Vishakha; Xu, Chao; Yue, Wei

Single-cell protein profiling defines cell populations associated with triple-negative breast cancer aggressiveness

单细胞蛋白谱分析确定了与三阴性乳腺癌侵袭性相关的细胞群

Barbora Kvokačková ,Radek Fedr ,Daniela Kužílková ,Jan Stuchlý ,Adéla Vávrová ,Jiří Navrátil ,Pavel Fabian ,Róbert Ondruššek ,Petra Ovesná ,Ján Remšík ,Jan Bouchal ,Tomáš Kalina ,Karel Souček