日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epigenetic control of PDX1 and NGN3 by a computationally designed PRC2 inhibitor enforces pancreatic endocrine differentiation from pluripotent stem cells.

通过计算机设计的 PRC2 抑制剂对 PDX1 和 NGN3 进行表观遗传控制,从而促进多能干细胞向胰腺内分泌分化。

Crisa Laura, Levy Shiri, Mar Dan, Bomsztyk Karol, Battle Stephanie, Gharib Sina, Lopez-Martinez Cecilia, McGrath Patrick, Mathieu Julie, Regier Marie, Ruohola-Baker Hannele, Cirulli Vincenzo

PDX1 Methylation, NGN3 and Pax6 Expression Levels in Pregnant Women with Gestational Diabetes Mellitus and their association with neonatal blood sugars and birth weight

妊娠期糖尿病孕妇PDX1甲基化、NGN3和Pax6表达水平及其与新生儿血糖和出生体重的关系

Su, Yuanyuan; Li, Jingjing; Chen, Limin; Lian, Hongnan; Qie, Yamin

The adipocyte-enriched secretory protein tetranectin exacerbates type 2 diabetes by inhibiting insulin secretion from β cells

富含脂肪细胞的分泌蛋白四联蛋白通过抑制 β 细胞的胰岛素分泌而加剧 2 型糖尿病

Fen Liu, Zixin Cai, Yan Yang, George Plasko, Piao Zhao, Xiangyue Wu, Cheng Tang, Dandan Li, Ting Li, Shanbiao Hu, Lei Song, Shaojie Yu, Ran Xu, Hairong Luo, Libin Fan, Ersong Wang, Zhen Xiao, Yujiao Ji, Rong Zeng, Rongxia Li, Juli Bai, Zhiguang Zhou, Feng Liu, Jingjing Zhang

Pro-α-cell-derived β-cells contribute to β-cell neogenesis induced by antagonistic glucagon receptor antibody in type 2 diabetic mice

前 α 细胞衍生的 β 细胞有助于 2 型糖尿病小鼠中拮抗性胰高血糖素受体抗体诱导的 β 细胞新生

Xiaona Cui, Jin Feng, Tianjiao Wei, Liangbiao Gu, Dandan Wang, Shan Lang, Kun Yang, Jin Yang, Hai Yan, Rui Wei, Tianpei Hong

Acarbose ameliorates spontaneous type‑2 diabetes in db/db mice by inhibiting PDX‑1 methylation

阿卡波糖通过抑制 PDX-1 甲基化改善 db/db 小鼠的自发性 2 型糖尿病

Diyi Zhou, Lijun Chen, Xin Mou

Intermittent administration of a leucine-deprived diet is able to intervene in type 2 diabetes in db/db mice

间歇性实施缺乏亮氨酸的饮食能够干预 db/db 小鼠的 2 型糖尿病

Siying Wei, Jingyu Zhao, Shuo Wang, Meiqin Huang, Yining Wang, Yan Chen

Intermittent administration of a fasting-mimicking diet intervenes in diabetes progression, restores β cells and reconstructs gut microbiota in mice

间歇性实施模拟禁食饮食可干预小鼠糖尿病进展、恢复 β 细胞并重建肠道菌群

Siying Wei #, Ruomei Han #, Jingyu Zhao, Shuo Wang, Meiqin Huang, Yining Wang, Yan Chen

Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium.

Ngn3(+)内分泌祖细胞控制胰腺导管上皮的命运和形态发生。

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

IA1 依赖于 NGN3,对内分泌胰腺的分化至关重要。

Mellitzer, Georg; Bonné, Stefan; Luco, Reini F; Van De Casteele, Mark; Lenne-Samuel, Nathalie; Collombat, Patrick; Mansouri, Ahmed; Lee, Jacqueline; Lan, Michael; Pipeleers, Daniel; Nielsen, Finn C; Ferrer, Jorge; Gradwohl, Gérard; Heimberg, Harry