日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Neuropeptide and cytokines expression in long COVID-19 related neuropsychological sequelae: insights into NK1R-mediated neuroinflammation and in silico therapeutic targeting

长期新冠肺炎相关神经心理后遗症中神经肽和细胞因子的表达：NK1R介导的神经炎症及其计算机模拟治疗靶向机制的深入研究

期刊:Frontiers in Cellular Neuroscience
影响因子:4
doi:10.3389/fncel.2026.1763029
Abdullah, Muhammad; Naz, Anam; Reznikov, Leah R; Qureshi, Javed Anver; Hasnain, Ammarah; Obaid, Ayesha; Ali, Amjed
肺炎
新冠
炎症
炎症/感染
神经科学
NK1
微生物学
细胞生物学
神经炎症
NK1R
免疫/内分泌
发表日期：2026
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Human Substance P Interactions with G Protein-Coupled Receptor NK1R Observed by NMR in Solution

溶液中核磁共振观察到人P物质与G蛋白偶联受体NK1R的相互作用

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c12553
Ge, Haoyi; Yang, Lingyun; Chen, Changran; Xu, Yuxin; Liu, Dongsheng; Wüthrich, Kurt
信号转导
Human
NK1R
NK1
发表日期：2025
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A Dual-Purpose Approach for an Anti-Emetic NK1R Antagonist as a Chemosensitizer and Cardioprotectant in a Preclinical Model of Triple-Negative Breast Cancer

在三阴性乳腺癌临床前模型中，一种具有双重作用的止吐NK1R拮抗剂作为化疗增敏剂和心脏保护剂

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26199353
Muñoz, Miguel; Coveñas, Rafael; Zuberi, Younus; Italia, Zara; Hoang, Tan; Italia, Zal; Robinson, Prema
肿瘤
肿瘤免疫
NK1
乳腺癌
NK1R
发表日期：2025
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Suppressing the Substance P-NK1R Signalling Protects Mice against Sepsis-Associated Acute Inflammatory Injury and Ferroptosis in the Liver and Lungs

抑制P物质-NK1R信号传导可保护小鼠免受脓毒症相关的肝脏和肺部急性炎症损伤和铁死亡的影响

期刊:Antioxidants
影响因子:6.6
doi:10.3390/antiox13030300
Zhu, Zhixing; Chambers, Stephen; Bhatia, Madhav
炎症
炎症/感染
信号转导
败血症
NK1
铁死亡
NK1R
发表日期：2024
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One-Day Versus Three-Day Dexamethasone with NK1RA for Patients Receiving Carboplatin and Moderate Emetogenic Chemotherapy: A Network Meta-analysis

接受卡铂和中度致吐化疗的患者中，单日与三日地塞米松联合NK1RA治疗的疗效比较：一项网络荟萃分析

期刊:Oncologist
影响因子:4.2
doi:10.1093/oncolo/oyac060
Watanabe, Daichi; Iihara, Hirotoshi; Fujii, Hironori; Makiyama, Akitaka; Nishida, Shohei; Suzuki, Akio
NK1R
NK1
发表日期：2022
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Upregulated expression of substance P and NK1R in blood monocytes and B cells of patients with allergic rhinitis and asthma

过敏性鼻炎和哮喘患者血液单核细胞和B细胞中P物质和NK1R表达上调

期刊:Clinical and Experimental Immunology
影响因子:3.8
doi:10.1093/cei/uxac074
Han, Peixuan; Chen, Liping; Chen, Dong; Yang, Ruiming; Wang, Wei; Liu, Jingyu; He, Shaoheng; Zhang, Huiyun
B细胞
哮喘
NK1
鼻炎
单核细胞
细胞生物学
NK1R
免疫/内分泌
发表日期：2022
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Neurokinin Receptor 1 (NK1R) Antagonist Aprepitant Enhances Hematoma Clearance by Regulating Microglial Polarization via PKC/p38MAPK/NFκB Pathway After Experimental Intracerebral Hemorrhage in Mice

神经激肽受体1 (NK1R) 拮抗剂阿瑞匹坦通过PKC/p38MAPK/NFκB通路调节小胶质细胞极化，从而增强小鼠实验性脑出血后的血肿清除。

期刊:Neurotherapeutics
影响因子:6.9
doi:10.1007/s13311-021-01077-8
Jin, Peng; Deng, Shuixiang; Sherchan, Prativa; Cui, Yuhui; Huang, Lei; Li, Gaigai; Lian, Lifei; Xie, Shucai; Lenahan, Cameron; Travis, Zachary D; Zhang, John H; Gong, Ye; Tang, Jiping
胶质细胞
信号转导
神经科学
MAPK/ERK
NK1
细胞生物学
PKC
NK1R
发表日期：2021
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Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity

具有广谱抗癌活性的碳水化合物基NK1R拮抗剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.1c00793
Recio, Rocío; Lerena, Patricia; Pozo, Esther; Calderón-Montaño, José Manuel; Burgos-Morón, Estefanía; López-Lázaro, Miguel; Valdivia, Victoria; Pernia Leal, Manuel; Mouillac, Bernard; Organero, Juan Ángel; Khiar, Noureddine; Fernández, Inmaculada
肿瘤
NK1R
NK1
肿瘤免疫
发表日期：2021
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The Effect of SP/NK1R on the Expression and Activity of Catalase and Superoxide Dismutase in Glioblastoma Cancer Cells

SP/NK1R对胶质母细胞瘤细胞中过氧化氢酶和超氧化物歧化酶表达及活性的影响

期刊:Biochemistry Research International
影响因子:3.4
doi:10.1155/2021/6620708.
Faranak Korfi,Hossein Javid,Reza Assaran Darban,Seyed Isaac Hashemy
细胞生物学
NK1
NK1R
发表日期：2021
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The SP/NK1R System-Mediated ROS Generation in GBM Cells through Inhibiting Glutaredoxin Protein

SP/NK1R系统通过抑制谷胱甘肽还原酶介导GBM细胞中ROS的生成

期刊:Neurology Research International
影响因子:2.8
doi:10.1155/2021/9966000
Mehrabani, Negeen; Vaezi Kakhki, Mohammad Reza; Javid, Hossein; Ebrahimi, Safieh; Hashemy, Seyed Isaac
细胞生物学
NK1R
NK1
发表日期：2021
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