NOX4相关文献与解析，生知库 | 链接生命科学的每一步

NOX4-derived oxidative DNA damage impairs thyroid differentiation through an epigenetic mechanism in BRAF-mutated radioactive iodine refractory papillary thyroid cancer cells.

NOX4 衍生的氧化性 DNA 损伤通过表观遗传机制损害 BRAF 突变的放射性碘难治性乳头状甲状腺癌细胞的甲状腺分化。

期刊:International Journal of Biological Sciences

Radom MickaÃ«lle, Buffet Camille, Cazarin Juliana, Harinquet Marylin, de Faria Caroline Coelho, BrayÃ© Floriane, Nobre Catline, Aglave Marine, Mesloub Yasmina, Dayris Thibault, Droin Nathalie, Godefroy Karine, Bani Mohamed-Amine, Ghuzlan Abir Al, Leboulleux Sophie, Lamartina Livia, Dupuy Corinne

Klotho protects the osteogenic function of human periodontal ligament stem cells in periodontitis by inhibiting NOX4-mediated ferroptosis

Klotho通过抑制NOX4介导的铁死亡来保护牙周炎中人牙周膜干细胞的成骨功能。

期刊:Stem Cell Research & Therapy

影响因子:7.3

doi:10.1186/s13287-026-04894-w

Lin, Chuanmiao; Wei, Junbin; Zhao, Tingting; Chen, Lingling; Rong, Shuxuan; Zhan, Junkun; Lai, Wenjia; Wang, Yan; Xie, Yunyi; Chen, Huan

Bu-Shen-Tian-Jing Formula alleviates oxidative-inflammatory stress in granulosa cells of polycystic ovary syndrome through AGEs-RAGE/NOX4/NF-ÎºB pathway.

补肾天经方通过 AGEs-RAGE/NOX4/NF-κB 通路减轻多囊卵巢综合征颗粒细胞的氧化炎症应激。

期刊:Chinese Medicine

影响因子:5.7

doi:10.1186/s13020-026-01333-z

Zhang Qing, Ren Jun, Ye Jiayu, Chen Fan, Xiang Fuying, Shi Biwei, Zhou Zhishan, Zhou Jinhong, Wang Fangfang, Qu Fan

Aging-Associated Nox4-Mediated Mitochondrial Reactive Oxygen Species and DNA Damage Promote Vascular Cell Reprogramming and Aortic Remodeling in Abdominal Aneurysms.

衰老相关的 Nox4 介导的线粒体活性氧和 DNA 损伤促进腹主动脉瘤血管细胞重编程和主动脉重塑。

期刊:Journal of the American Heart Association

影响因子:5.3

doi:10.1161/JAHA.125.044949

Vendrov Aleksandr E, Chamon Jamille Silveira Fernandes, Levin Julia, Hayami Takayuki, Madamanchi Chaitanya, Salmon Morgan, Madamanchi Nageswara R

Phycocyanobilin as a Functional Food-Derived Nutraceutical Candidate for Modulating the RAGE/NOX4 Axis in Neurodegenerative Disorders.

藻蓝蛋白作为一种功能性食品衍生营养保健品，可用于调节神经退行性疾病中的 RAGE/NOX4 轴。

期刊:Nutrients

影响因子:5

doi:10.3390/nu18040617

Lai Mei Chou, Tzeng Yu-Cheng, Liu Wayne Young, Liu I-Min

Fusobacterium nucleatum drives endothelial cell senescence by disrupting NOX4/NRF2 balance

具核梭杆菌通过破坏NOX4/NRF2平衡驱动内皮细胞衰老。

期刊:mBio

影响因子:4.7

doi:10.1128/mbio.03441-25

Wu, Peiyao; Zhou, Jieyu; Wang, Jun; Wu, Yafei; Wang, Hui; Zhao, Lei

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

[更正] 二甲双胍通过 AMPK 依赖性抑制 NOX4 对心肌缺血再灌注损伤的保护作用

期刊:Molecular Medicine Reports

影响因子:3.5

doi:10.3892/mmr.2025.13752

Shi, Yan; Hou, Shu-Ai

4-Methylesculetin Ameliorates Hepatic Insulin Resistance in HepG2 Cells Through AMPK/FOXO1, PI3K/AKT/GSK3β Pathways and SIRT1/NOX4 Axis

4-甲基七叶内酯通过AMPK/FOXO1、PI3K/AKT/GSK3β通路和SIRT1/NOX4轴改善HepG2细胞的肝脏胰岛素抵抗

期刊:Journal of Diabetes Research

影响因子:3.4

doi:10.1155/jdr/8023146

Su, Xiaohua; Du, Yuhang; Yang, Yang; Zhao, Yige; Zhao, Hongbin; Xie, Jiamei; Shan, Ziyi; Wang, Menglu; Huang, Zhiyun; Fu, Wanxin; Wan, Anfeng; An, Yongcheng; Zhao, Baosheng

Investigation into the protective effects of protocatechuic acid in bleomycin-induced pulmonary remodeling and fibrosis in rats: role of MMP-2/TIMP-1 and CTGF/NOX4 pathway

探讨原儿茶酸对博来霉素诱导的大鼠肺重塑和纤维化的保护作用：MMP-2/TIMP-1和CTGF/NOX4通路的作用

期刊:Naunyn-Schmiedebergs Archives of Pharmacology

影响因子:3.1

doi:10.1007/s00210-025-04410-6

Elgohary, Rania; Abd Elwahab, Sahar; Salama, Abeer

A spinal USP7-Bach1 positive feedback loop drives NOX4-mediated ferroptosis in neuropathic pain.

脊髓 USP7-Bach1 正反馈环路驱动 NOX4 介导的铁死亡，从而导致神经性疼痛。

NOX4-derived oxidative DNA damage impairs thyroid differentiation through an epigenetic mechanism in BRAF-mutated radioactive iodine refractory papillary thyroid cancer cells.

NOX4 衍生的氧化性 DNA 损伤通过表观遗传机制损害 BRAF 突变的放射性碘难治性乳头状甲状腺癌细胞的甲状腺分化。

Klotho protects the osteogenic function of human periodontal ligament stem cells in periodontitis by inhibiting NOX4-mediated ferroptosis

Klotho通过抑制NOX4介导的铁死亡来保护牙周炎中人牙周膜干细胞的成骨功能。

Bu-Shen-Tian-Jing Formula alleviates oxidative-inflammatory stress in granulosa cells of polycystic ovary syndrome through AGEs-RAGE/NOX4/NF-ÎºB pathway.

补肾天经方通过 AGEs-RAGE/NOX4/NF-κB 通路减轻多囊卵巢综合征颗粒细胞的氧化炎症应激。

Aging-Associated Nox4-Mediated Mitochondrial Reactive Oxygen Species and DNA Damage Promote Vascular Cell Reprogramming and Aortic Remodeling in Abdominal Aneurysms.

衰老相关的 Nox4 介导的线粒体活性氧和 DNA 损伤促进腹主动脉瘤血管细胞重编程和主动脉重塑。

Phycocyanobilin as a Functional Food-Derived Nutraceutical Candidate for Modulating the RAGE/NOX4 Axis in Neurodegenerative Disorders.

藻蓝蛋白作为一种功能性食品衍生营养保健品，可用于调节神经退行性疾病中的 RAGE/NOX4 轴。

Fusobacterium nucleatum drives endothelial cell senescence by disrupting NOX4/NRF2 balance

具核梭杆菌通过破坏NOX4/NRF2平衡驱动内皮细胞衰老。

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

[更正] 二甲双胍通过 AMPK 依赖性抑制 NOX4 对心肌缺血再灌注损伤的保护作用

4-Methylesculetin Ameliorates Hepatic Insulin Resistance in HepG2 Cells Through AMPK/FOXO1, PI3K/AKT/GSK3β Pathways and SIRT1/NOX4 Axis

4-甲基七叶内酯通过AMPK/FOXO1、PI3K/AKT/GSK3β通路和SIRT1/NOX4轴改善HepG2细胞的肝脏胰岛素抵抗

Investigation into the protective effects of protocatechuic acid in bleomycin-induced pulmonary remodeling and fibrosis in rats: role of MMP-2/TIMP-1 and CTGF/NOX4 pathway

探讨原儿茶酸对博来霉素诱导的大鼠肺重塑和纤维化的保护作用：MMP-2/TIMP-1和CTGF/NOX4通路的作用