AXIN1相关文献与解析，生知库 | 链接生命科学的每一步

AXIN1 Polymorphisms Potentially Modulate Parkinson's Disease Susceptibility: A Cross-Sectional Study in Northern Han Chinese and White Populations

AXIN1多态性可能影响帕金森病易感性：一项针对北方汉族和白种人群的横断面研究

期刊:Neurology and Therapy

影响因子:4.8

doi:10.1007/s40120-025-00864-1

Kong, Zhen; Yu, Ran; Li, Chengqian; He, Qiqing; Zhou, Yuting; Zhang, Xue; Li, Yaqing; Xie, Anmu; Hou, Binghui

Hepatocellular carcinoma-linked AXIN1 mutations drive low Wnt/β-catenin activity enabling niche-independent growth and YAP/TAZ signaling

与肝细胞癌相关的AXIN1突变导致Wnt/β-catenin活性降低，从而促进细胞在非依赖微环境的生长和YAP/TAZ信号传导。

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2025.114501

Venhuizen, Anton J; van Os, Yvanka; Kaptein, Milo L; Aarts, Marleen T; Xanthakis, Despina; Jordens, Ingrid; Maurice, Madelon M

An expanded polyglutamine in ATAXIN1 results in a loss-of-function that exacerbates severity of Multiple Sclerosis in an EAE mouse model

ATAXIN1 中多聚谷氨酰胺的扩增导致其功能丧失，从而加剧 EAE 小鼠模型中多发性硬化症的严重程度。

期刊:Journal of Neuroinflammation

影响因子:10.1

doi:10.1186/s12974-025-03450-2

Talukdar, Gourango; Duvick, Lisa; Yang, Praseuth; O'Callaghan, Brennon; Fuchs, Gavin J; Cvetanovic, Marija; Orr, Harry T

SMURF2 inhibition attenuates cardiac hypertrophy through blocking ubiquitination degradation of AXIN1.

SMURF2 抑制剂通过阻断 AXIN1 的泛素化降解来减轻心脏肥大。

期刊:Acta Pharmacologica Sinica

影响因子:8.4

doi:10.1038/s41401-025-01597-5

Kang Ying, Zu Yan, Fan Qi-Yao, Liu Xia-Meng, Chen Shi-Qing, Ruan Liu-Liu, Tang Xin, Xie Li-Ping, Ji Yong

Wnt target IQGAP3 promotes Wnt signaling via disrupting Axin1-CK1α interaction

Wnt靶蛋白IQGAP3通过破坏Axin1-CK1α相互作用来促进Wnt信号通路。

期刊:Oncogene

影响因子:6.9

doi:10.1038/s41388-025-03512-y.

Muhammad Bakhait Rahmat,Aashiq Hussain,Yu Xuan Teh,Bibek Dutta,Sumedha Pundrik,Dennis Kappei,Yoshiaki Ito

AXIN1, STAMBP, ST1A1, CDCP1, and SIRT2 Validated as Myasthenia Gravis Biomarkers: A Comparative Proteomic Study With MS, CIDP, and Controls

AXIN1、STAMBP、ST1A1、CDCP1 和 SIRT2 被验证为重症肌无力生物标志物：一项与 MS、CIDP 和对照组的比较蛋白质组学研究

期刊:European Journal of Neurology

影响因子:3.9

doi:10.1111/ene.70426

Bhandage, Amol K; Hoffmann, Sarah; Dusemund, Carla; Stascheit, Frauke; Huang, Yu-Fang; Eriksson, Niclas; Gabrysch, Katja; Meisel, Andreas; Punga, Anna Rostedt

Complete remission in an advanced hepatocellular carcinoma patient with AXIN1 mutation after systemic therapy: A case report

一例AXIN1突变晚期肝细胞癌患者经全身治疗后完全缓解：病例报告

期刊:Heliyon

影响因子:3.6

doi:10.1016/j.heliyon.2025.e42010

Ran, Yihong; Huang, Xiaozhun; Che, Xu; Chen, Dong

Syntaxin clusters and cholesterol affect the mobility of Syntaxin1a.

Syntaxin 簇和胆固醇影响 Syntaxin1a 的流动性。

期刊:Biophysical Journal

影响因子:3.1

doi:10.1016/j.bpj.2024.01.012

High-Frequency Mutations in TP53, AXIN1, CTNNB1, and KRAS, and Polymorphisms in JAK1 Genes Among Mongolian HCC Patients

蒙古族肝细胞癌患者中TP53、AXIN1、CTNNB1和KRAS基因的高频突变以及JAK1基因的多态性

期刊:Cancer Reports

影响因子:1.9

doi:10.1002/cnr2.70227

Bold, Nomin; Buyanbat, Khurelsukh; Enkhtuya, Ariya; Myagmar, Nomin; Batbayar, Gerelsuren; Sandag, Zolzaya; Damdinbazar, Dolgion; Oyunbat, Nomuun; Boldbaatar, Tuul; Enkhbaatar, Ankhbayar; Baatarjav, Gan-Erdene; Nanzaddorj, Taivan; Oyunsuren, Tsendsuren; Davaakhuu, Gantulga

Axin1 stabilizes S-opsin and maintains cone photoreceptor survival by inhibiting GSK3Î² activity.

Axin1 通过抑制 GSK3β 活性来稳定 S-视蛋白并维持视锥细胞光感受器的存活。

AXIN1 Polymorphisms Potentially Modulate Parkinson's Disease Susceptibility: A Cross-Sectional Study in Northern Han Chinese and White Populations

AXIN1多态性可能影响帕金森病易感性：一项针对北方汉族和白种人群的横断面研究

Hepatocellular carcinoma-linked AXIN1 mutations drive low Wnt/β-catenin activity enabling niche-independent growth and YAP/TAZ signaling

与肝细胞癌相关的AXIN1突变导致Wnt/β-catenin活性降低，从而促进细胞在非依赖微环境的生长和YAP/TAZ信号传导。

An expanded polyglutamine in ATAXIN1 results in a loss-of-function that exacerbates severity of Multiple Sclerosis in an EAE mouse model

ATAXIN1 中多聚谷氨酰胺的扩增导致其功能丧失，从而加剧 EAE 小鼠模型中多发性硬化症的严重程度。

SMURF2 inhibition attenuates cardiac hypertrophy through blocking ubiquitination degradation of AXIN1.

SMURF2 抑制剂通过阻断 AXIN1 的泛素化降解来减轻心脏肥大。

Wnt target IQGAP3 promotes Wnt signaling via disrupting Axin1-CK1α interaction

Wnt靶蛋白IQGAP3通过破坏Axin1-CK1α相互作用来促进Wnt信号通路。

AXIN1, STAMBP, ST1A1, CDCP1, and SIRT2 Validated as Myasthenia Gravis Biomarkers: A Comparative Proteomic Study With MS, CIDP, and Controls

AXIN1、STAMBP、ST1A1、CDCP1 和 SIRT2 被验证为重症肌无力生物标志物：一项与 MS、CIDP 和对照组的比较蛋白质组学研究

Complete remission in an advanced hepatocellular carcinoma patient with AXIN1 mutation after systemic therapy: A case report

一例AXIN1突变晚期肝细胞癌患者经全身治疗后完全缓解：病例报告

Syntaxin clusters and cholesterol affect the mobility of Syntaxin1a.

Syntaxin 簇和胆固醇影响 Syntaxin1a 的流动性。

High-Frequency Mutations in TP53, AXIN1, CTNNB1, and KRAS, and Polymorphisms in JAK1 Genes Among Mongolian HCC Patients

蒙古族肝细胞癌患者中TP53、AXIN1、CTNNB1和KRAS基因的高频突变以及JAK1基因的多态性