日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Enhancer remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm

OTX2介导的增强子重塑指导哺乳动物终末内胚层的分化和模式形成

Ly-Sha Ee ,Daniel Medina-Cano ,Emily Goetzler ,Christopher Uyehara ,Clayton Schwarz ,Eralda Salataj ,Subhashini Madhuranath ,Todd Evans ,Anna-Katerina Hadjantonakis ,Effie Apostolou ,Alexander Polyzos ,Thomas Vierbuchen ,Matthias Stadtfeld

Distinct dynamics of parental 5-hydroxymethylcytosine during human preimplantation development regulate early lineage gene expression

人类植入前发育过程中亲本 5-羟甲基胞嘧啶的独特动态调节早期谱系基因表达

Dan Liang #, Rui Yan #, Xin Long #, Dongmei Ji #, Bing Song, Mengyao Wang, Fan Zhang, Xin Cheng, Fengyuan Sun, Ran Zhu, Xinling Hou, Tianjuan Wang, Weiwei Zou, Ying Zhang, Zhixin Pu, Jing Zhang, Zhiguo Zhang, Yajing Liu, Yuqiong Hu, Xiaojin He, Yunxia Cao, Fan Guo

One-step cell biomanufacturing platform: porous gelatin microcarrier beads promote human embryonic stem cell-derived midbrain dopaminergic progenitor cell differentiation in vitro and survival after transplantation in vivo

一步式细胞生物制造平台:多孔明胶微载体珠促进人胚胎干细胞来源的中脑多巴胺能祖细胞在体外分化,并提高其在体内移植后的存活率

Lin Feng ,Da Li ,Yao Tian ,Chengshun Zhao ,Yun Sun ,Xiaolong Kou ,Jun Wu ,Liu Wang ,Qi Gu ,Wei Li ,Jie Hao ,Baoyang Hu ,Yukai Wang

Zbtb11 interacts with Otx2 and patterns the anterior neuroectoderm in Xenopus

Zbtb11 与 Otx2 相互作用,并调控爪蟾前神经外胚层的模式形成

Yumeko Satou-Kobayashi ,Shuji Takahashi ,Yoshikazu Haramoto ,Makoto Asashima ,Masanori Taira

The OTX2 Gene Induces Tumor Growth and Triggers Leptomeningeal Metastasis by Regulating the mTORC2 Signaling Pathway in Group 3 Medulloblastomas

OTX2基因通过调节3组髓母细胞瘤中的mTORC2信号通路诱导肿瘤生长并触发软脑膜转移

Elisabet Ampudia-Mesias ,Charles S Cameron ,Eunjae Yoo ,Marcus Kelly ,Sarah M Anderson ,Riley Manning ,Juan E Abrahante Lloréns ,Christopher L Moertel ,Hyungshin Yim ,David J Odde ,Nurten Saydam ,Okay Saydam

O-GlcNAcylation regulates OTX2's proteostasis

O-GlcNAc糖基化调节OTX2的蛋白质稳态

Eugenia Wulff-Fuentes,Jeffrey Boakye,Kaeley Kroenke,Rex R Berendt,Carla Martinez-Morant,Michaela Pereckas,John A Hanover,Stephanie Olivier-Van Stichelen

Mutations in BCOR, a co-repressor of CRX/OTX2, are associated with early-onset retinal degeneration

BCOR(CRX/OTX2 的共抑制因子)的突变与早发性视网膜变性相关。

Maéva Langouët,Christine Jolicoeur,Awais Javed,Pierre Mattar,Micah D Gearhart,Stephen P Daiger,Mette Bertelsen,Lisbeth Tranebjærg,Nanna D Rendtorff,Karen Grønskov,Catherine Jespersgaard,Rui Chen,Zixi Sun,Hui Li,Najmeh Alirezaie,Jacek Majewski,Vivian J Bardwell,Ruifang Sui,Robert K Koenekoop,Michel Cayouette

A Stage-Specific OTX2 Regulatory Network and Maturation-Associated Gene Programs Are Inherent Barriers to RPE Neural Competency

阶段特异性OTX2调控网络和成熟相关基因程序是RPE神经功能发育的固有障碍

Jared A Tangeman ,J Raúl Pérez-Estrada ,Emily Van Zeeland ,Lin Liu ,Alexandra Danciutiu ,Erika Grajales-Esquivel ,Byran Smucker ,Chun Liang ,Katia Del Rio-Tsonis

Tyramide signal amplification coupled with multiple immunolabeling and RNAScope in situ hybridization in formaldehyde-fixed paraffin-embedded human fetal brain

酪胺信号放大结合多重免疫标记和 RNAScope 原位杂交在甲醛固定石蜡包埋的人胎脑中

Ayman Alzu'bi, Niveditha Sankar, Moira Crosier, Janet Kerwin, Gavin J Clowry

Initiation of Otx2 expression in the developing mouse retina requires a unique enhancer and either Ascl1 or Neurog2 activity

在发育中的小鼠视网膜中,Otx2表达的启动需要一种独特的增强子以及Ascl1或Neurog2的活性。

Michael L Kaufman ,Noah B Goodson ,Ko Uoon Park ,Michael Schwanke ,Emma Office ,Sophia R Schneider ,Joy Abraham ,Austin Hensley ,Kenneth L Jones ,Joseph A Brzezinski