日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Knockout of PAK1 and PAK4 supresses tumour growth associated with vasculogenic mimicry inhibition through EphA2-VE-cadherin-MCAM pathway

敲除PAK1和PAK4可通过EphA2-VE-cadherin-MCAM通路抑制血管生成拟态,从而抑制肿瘤生长。

Ansardamavandi, Arian; Dumesny, Chelsea; Ellis, Sarah; Ang, Ching-Seng; Nikfarjam, Mehrdad; He, Hong

Diagnostic and prognostic performance of PAK1 methylation in patients with hepatocellular carcinoma undergoing liver transplantation

PAK1甲基化在接受肝移植的肝细胞癌患者中的诊断和预后性能

Hwang, Shin; Ko, Hyo Jung; Tak, Eunyoung; Lee, Kyoung-Jin; Lee, Yun-Kyu

PAK1 inhibition synergistically enhances the anti-tumor efficacy of PARP inhibitors in ovarian cancers

PAK1抑制可协同增强PARP抑制剂在卵巢癌中的抗肿瘤疗效

Li, Changying; Li, Xinyan; Gao, Ming; Deng, Min; Li, Ye-Xiong; Lou, Zhenkun

Targeting PAK1 suppresses tumor progression by promoting mRNA decay of oncogenic factors and enhancing chemotherapeutic efficacy in colorectal cancer

靶向PAK1可通过促进致癌因子mRNA的降解来抑制肿瘤进展,并增强结直肠癌的化疗疗效。

Pan, Rongtian; Zou, Renrui; Sui, Ying; Wu, Fei; Wang, Dongfeng; Zhang, Yuan; Yu, Shaorong

Nox1/PAK1 is required for angiotensin II-induced vascular inflammation and abdominal aortic aneurysm formation

Nox1/PAK1是血管紧张素II诱导的血管炎症和腹主动脉瘤形成所必需的

He, Hui; Jiang, Tianyu; Ding, Meng; Zhu, Yuan; Xu, Xiaoting; Huang, Yashuang; Yu, Wenfeng; Ou, Hailong

PAK1 inhibitor NVS-PAK1-1 preserves dendritic spines in amyloid/tau exposed neurons and 5xFAD mice.

PAK1 抑制剂 NVS-PAK1-1 可保护淀粉样蛋白/tau 暴露的神经元和 5xFAD 小鼠的树突棘。

Beta cell-specific PAK1 enrichment ameliorates diet-induced glucose intolerance in mice by promoting insulin biogenesis and minimising beta cell apoptosis

β细胞特异性PAK1富集可通过促进胰岛素生物合成和减少β细胞凋亡来改善饮食诱导的小鼠葡萄糖耐受不良

Ahn, Miwon; Dhawan, Sangeeta; McCown, Erika M; Garcia, Pablo A; Bhattacharya, Supriyo; Stein, Roland; Thurmond, Debbie C

PAK1 regulates oligodendroglial proliferation and repopulation in homeostatic and demyelinating brain

PAK1在稳态和脱髓鞘脑中调节少突胶质细胞的增殖和再生。

Yan Wang ,Bokyung Kim ,Xiangyi Shi ,Huimin Chen ,Joohyun Park ,Meina Zhu ,Evelyn M Wong ,Audrey Y Park ,Jonathan Chernoff ,Fuzheng Guo

Targeting PAK1 or PAK4 Uncovers Different Mechanisms of Vascular Reprogramming in Pancreatic Cancer.

靶向 PAK1 或 PAK4 揭示胰腺癌血管重编程的不同机制。

Ansardamavandi Arian, Dumesny Chelsea, Ellis Sarah, Ang Ching-Seng, Nikfarjam Mehrdad, He Hong

The Biological Role of the Signal Transducer and Activator of Transcription 1 (STAT1)-miR-221/222-3p-p21 Activated Kinase 1 (PAK1) Axis in Experimental Periodontitis

信号转导和转录激活因子1 (STAT1)-miR-221/222-3p-p21活化激酶1 (PAK1)轴在实验性牙周炎中的生物学作用

Wu, Yun; Ji, Yaoting; Mu, Rui; Pan, Jiawen; Fan, Ruixin; Zhao, Yan; Liang, Shanshan