日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

PARP1-HPF1 structure and dynamics on nicked DNA suggest a mechanism for acute and localized ADP-ribosylation

PARP1-HPF1 在缺口 DNA 上的结构和动力学揭示了一种急性局部 ADP 核糖基化的机制

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69375-3
Sverzhinsky, Aleksandr; Xue, Huijun; Langelier, Marie-France; Muniz Corrêa, Marcelo V; Del Mundo, Joshua; Classen, Scott; Hammel, Michal; Rothenberg, Eli; Pascal, John M
PARP
PARP1
发表日期：2026
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Tumor metabolic adaptation induced by L-asparaginase reveals a vulnerability to PARP1/2 inhibitor in B-cell lymphomas.

L-天冬酰胺酶诱导的肿瘤代谢适应揭示了B细胞淋巴瘤对PARP1/2抑制剂的脆弱性。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-70066-2
Aussel Anaïs, Nemazanyy Ivan, Vandenberghe Ashaina, Meola Pauline, Dorat Noémie, Paul Rachel, Habbouche Lama, Exposito Laurie, Nottet Nicolas, Petrilli Virginie, Chiche Edmond, Mounier Nicolas, Marchetti Sandrine, Chaveroux Cédric, Ricci Jean-Ehrland, Chiche Johanna
淋巴瘤
细胞生物学
B细胞
PARP
PARP1
发表日期：2026
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Versatile and sensitive detection of mono- and poly(ADP-ribosyl)ation reveals XRCC1-dependent remodelling of PARP1 signalling.

对单(ADP-核糖基)化和多(ADP-核糖基)化的多功能和灵敏检测揭示了 XRCC1 依赖的 PARP1 信号重塑。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-71311-4
Dauben Helen, Mihaljević Mihaela, Kolvenbach Andreas, Palumbieri Maria Dilia, Kapsali Chrysi, Huppertz Ina, Matić Ivan
信号转导
RCC1
PARP
PARP1
XRCC1
发表日期：2026
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Lactobacillus Salivarius-Derived Indole-3-Acetic Acid Promotes AHR-PARP1 Axis-Mediated DNA Repair to Mitigate Intestinal Aging

唾液乳杆菌衍生的吲哚-3-乙酸促进AHR-PARP1轴介导的DNA修复，从而延缓肠道衰老

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202515794
Cao, Zheng; Zhang, Cui; Lei, Hehua; Lin, Weichuan; Yu, Wenkai; Gao, Xin; He, Yanmeng; Li, Xinzhi; Xiang, Qingwei; Zhang, Zhiwen; Luo, Weifei; Patterson, Andrew D; Zhang, Limin; Chen, Gang
PARP
AHR
衰老
PARP1
发表日期：2026
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Correction to "ARF induction in response to DNA strand breaks is regulated by PARP1"

更正“DNA链断裂后ARF的诱导受PARP1调控”

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkag013
PARP1
信号转导
ARF
PARP
发表日期：2026
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HPF1 regulates the formation of FUS-dependent compartments by PARP1 and PARP2 activation on damaged DNA

HPF1通过激活受损DNA上的PARP1和PARP2来调控FUS依赖性区室的形成。

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkag183
Singatulina, Anastasia S; Sukhanova, Maria V; Hamon, Loic; Kutuzov, Mikhail M; Pastré, David; Lavrik, Olga I
PARP1
信号转导
FUS
ARP2
PARP
发表日期：2026
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PARP1 and PARP2 are dispensable for DNA repair by microhomology-mediated end-joining at double-ended DSBs.

PARP1 和 PARP2 对于通过微同源介导的末端连接修复双端 DSB 的 DNA 损伤来说并非必需。

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf1437
Ortega Raquel, Taylor Erin R, Whitehead Sophie M, Danhorn Thomas, Bitler Benjamin G, Arnoult Nausica
ARP2
PARP
PARP1
发表日期：2026
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Circular RNA circATM binds PARP1 to suppress Wnt/β-catenin signaling and induce cell cycle arrest in gastric cancer cells.

环状RNA circATM与PARP1结合，抑制Wnt/β-catenin信号传导，诱导胃癌细胞细胞周期停滞。

期刊:Journal of Advanced Research
影响因子:13
doi:10.1016/j.jare.2025.04.033
Zhu Xiaohui, Zhang Xiaojing, Qin Ying, Chen Yang, Feng Xianling, Deng Shiqi, Hu Fan, Yuan Yuan, Luo Xiaonuan, Du Kaining, Chang Shanshan, Fan Xinmin, Ashktorab Hassan, Smoot Duane, Jin Zhe, Peng Yin
胃癌
细胞生物学
ATM
PARP
PARP1
发表日期：2026
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A SERS-based biosensor for optical monitoring of PARP1 trapping dynamics and high-throughput screening of modulators

一种基于SERS的生物传感器，用于PARP1捕获动力学的光学监测和调节剂的高通量筛选

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-026-04143-5
Xu, Shizhi; Wang, Ziming; Li, Baizhi; Wang, Jiayu; Fang, Shai; Huang, Wei; Liu, Zhiyi; Li, Hongrui; Xiang, Jinbao; Xu, Shuping; Liang, Chongyang
PARP
PARP1
发表日期：2026
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PARP1 stabilizes FOXN3 to suppress pulmonary fibrosis through p38-related feedback regulation.

PARP1 通过 p38 相关的反馈调节稳定 FOXN3，从而抑制肺纤维化。

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.ady1681
PARP1
PARP
发表日期：2026
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