PDIA4相关文献与解析，生知库 | 链接生命科学的每一步

Single-cell transcriptomics identifies PDIA4 as a marker of progression and therapeutic vulnerability in multiple myeloma

单细胞转录组学鉴定出PDIA4是多发性骨髓瘤进展和治疗脆弱性的标志物

Yu, Wenjie; Zhan, Jiamin; Wang, Yanxia; Cao, Xu; Yu, Aoyang; Rao, Yuexuan; Huang, Can; Zhang, Xuan; Lu, Shunv; Liu, Yanhua; Chen, Chong; Li, Zhenyu

多发性骨髓瘤

Correction: Non-genetic inactivation of caspase-3 and P53 increases cancer cell fitness by PDIA4 redistribution

更正：caspase-3 和 P53 的非基因失活通过 PDIA4 的重新分布增强癌细胞的适应性。

期刊:Oncogene

影响因子:7.3

doi:10.1038/s41388-025-03616-5

Twito, Gal; Abu Abayed, Faiza Amterat; Gilad, Ayelet; Biadsy, Suma; Gavriel, Noa; Sheikh Suliman, Suad; Mizrahi, Yarden; Megged, Hila; Tenenboim, Mor; Abu-Freha, Naim; Igbaria, Aeid

Non-genetic inactivation of caspase-3 and P53 increases cancer cell fitness by PDIA4 redistribution

非基因介导的 caspase-3 和 P53 失活通过 PDIA4 重分布增强癌细胞的适应性。

期刊:Oncogene

影响因子:7.3

doi:10.1038/s41388-025-03606-7

Twito, Gal; Abu Abayed, Faiza Amterat; Gilad, Ayelet; Biadsy, Suma; Gavriel, Noa; Sheikh Suliman, Suad; Mizrahi, Yarden; Megged, Hila; Tenenboim, Mor; Abu-Freha, Naim; Igbaria, Aeid

Downregulation of PDIA4 inhibits proliferation and migration in human oral squamous cell carcinoma.

PDIA4 的下调抑制人类口腔鳞状细胞癌的增殖和迁移。

期刊:Hereditas

影响因子:2.5

doi:10.1186/s41065-025-00594-2

Hu Yue, Zhang Wei, Zhang Fuyu, Liu Qiaoyun, Yang Hao

PDIA4 Correlates with Poor Prognosis and is a Potential Biomarker in Glioma

PDIA4与不良预后相关，是胶质瘤的潜在生物标志物

期刊:Oncotargets and Therapy

影响因子:2.8

doi:10.2147/OTT.S287931

Li, Haoyu; Liu, Qing; Xiao, Kai; He, Zhengxi; Wu, Chao; Sun, Jianjun; Chen, Xin; Chen, Suhua; Yang, Jun; Ma, Qianquan; Su, Jun

EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD

EDEM2 与 TXNDC11 稳定地形成二硫键，催化哺乳动物糖蛋白 ERAD 中的第一个甘露糖修剪步骤

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.53455

Ginto George #, Satoshi Ninagawa #, Hirokazu Yagi, Taiki Saito, Tokiro Ishikawa, Tetsushi Sakuma, Takashi Yamamoto, Koshi Imami, Yasushi Ishihama, Koichi Kato, Tetsuya Okada, Kazutoshi Mori

Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response

长白细胞介素-22 结合蛋白同工型-1 是未折叠蛋白反应的细胞内激活剂

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2018.02934

Paloma Gómez-Fernández, Andoni Urtasun, Adrienne W Paton, James C Paton, Francisco Borrego, Devin Dersh, Yair Argon, Iraide Alloza, Koen Vandenbroeck

Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57

硝唑尼特通过靶向融合蛋白折叠来抑制副粘液病毒复制：糖蛋白特异性硫醇氧化还原酶 ERp57 的作用

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-018-28172-9

Sara Piacentini, Simone La Frazia, Anna Riccio, Jens Z Pedersen, Alessandra Topai, Orazio Nicolotti, Jean-Francois Rossignol, M Gabriella Santoro

Early-onset torsion dystonia: a novel high-throughput yeast genetic screen for factors modifying protein levels of torsinAΔE

早发性扭转性肌张力障碍：一种新的高通量酵母基因筛选方法，用于筛选改变 torsinAΔE 蛋白质水平的因素

期刊:Disease Models & Mechanisms

影响因子:4

doi:10.1242/dmm.029926

Lucía F Zacchi, John C Dittmar, Michael J Mihalevic, Annette M Shewan, Benjamin L Schulz, Jeffrey L Brodsky, Kara A Bernstein

Defects in PDIA4 increase individuals' susceptibility to congenital heart disease.

PDIA4 缺陷会增加个体患先天性心脏病的风险。

Single-cell transcriptomics identifies PDIA4 as a marker of progression and therapeutic vulnerability in multiple myeloma

单细胞转录组学鉴定出PDIA4是多发性骨髓瘤进展和治疗脆弱性的标志物

Correction: Non-genetic inactivation of caspase-3 and P53 increases cancer cell fitness by PDIA4 redistribution

更正：caspase-3 和 P53 的非基因失活通过 PDIA4 的重新分布增强癌细胞的适应性。

Non-genetic inactivation of caspase-3 and P53 increases cancer cell fitness by PDIA4 redistribution

非基因介导的 caspase-3 和 P53 失活通过 PDIA4 重分布增强癌细胞的适应性。

Downregulation of PDIA4 inhibits proliferation and migration in human oral squamous cell carcinoma.

PDIA4 的下调抑制人类口腔鳞状细胞癌的增殖和迁移。

PDIA4 Correlates with Poor Prognosis and is a Potential Biomarker in Glioma

PDIA4与不良预后相关，是胶质瘤的潜在生物标志物

EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD

EDEM2 与 TXNDC11 稳定地形成二硫键，催化哺乳动物糖蛋白 ERAD 中的第一个甘露糖修剪步骤

Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response

长白细胞介素-22 结合蛋白同工型-1 是未折叠蛋白反应的细胞内激活剂

Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57

硝唑尼特通过靶向融合蛋白折叠来抑制副粘液病毒复制：糖蛋白特异性硫醇氧化还原酶 ERp57 的作用

Early-onset torsion dystonia: a novel high-throughput yeast genetic screen for factors modifying protein levels of torsinAΔE

早发性扭转性肌张力障碍：一种新的高通量酵母基因筛选方法，用于筛选改变 torsinAΔE 蛋白质水平的因素