PER1相关文献与解析，生知库 | 链接生命科学的每一步

Pérez-Escudero, Natalia; Cabas, Isabel; Corbalán-Vélez, Raúl; Martínez-Menchón, Teresa; Ferri, Belén; Cayuela, María L; García-Moreno, Diana; García-Ayala, Alfonsa; Mulero, Victoriano

炎症

炎症/感染

PER1

Integrated Genomic and Transcriptomic Study Reveals MAPK11 and PER1 as Important Obesity Susceptibility Genes in a High-Risk Hispanic/Latino Population

整合基因组学和转录组学研究揭示 MAPK11 和 PER1 是高危西班牙裔/拉丁裔人群中重要的肥胖易感基因

期刊:Circulation-Genomic and Precision Medicine

影响因子:5.5

doi:10.1161/CIRCGEN.125.005298

Kim, Daeeun; Polikowsky, Hannah G; Highland, Heather M; Chen, Hung-Hsin; Zhu, Wanying; Zhang, Xinruo; Gillman, Madeline G; Frankel, Elizabeth G; Roshani, Rashedeh; Landman, Joshua M; Wang, Yujie; Young, Kristin L; Anwar, Mohammad Yaser; Krishnan, Mohanraj; Buchanan, Victoria L; Berndt, Sonja I; Arias, Joshua D; Raffield, Laura M; Gutierrez, Absalon D; Bishehsari, Faraz; Lee, Miryoung; McCormick, Joseph B; Fisher-Hoch, Susan P; Below, Jennifer E; North, Kari E; Graff, Mariaelisa

GPER1 as a therapeutic target in MASLD: evidence for steatosis attenuation by agonist G1 in preclinical models.

GPER1 作为 MASLD 的治疗靶点：临床前模型中激动剂 G1 可减轻脂肪变性的证据。

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2026.1764287

Correction: AOH induces oxidative stress and DNA damage in ovarian cancer cells via modulation of GPER1 and HIF1α/PI3K/CLDNs signaling pathway

更正：AOH通过调节GPER1和HIF1α/PI3K/CLDNs信号通路诱导卵巢癌细胞氧化应激和DNA损伤

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-026-36730-9

Kozieł-Leszczyńska, Marta Justyna; Habrowska-Górczyńska, Dominika Ewa; Leszczyński, Kacper Piotr; Urbanek, Kinga Anna; Piastowska-Ciesielska, Agnieszka Wanda; Kowalska, Karolina

N-(2-Hydroxyphenyl)-2-propylpentanamide Modulates HDAC1 and GPER1 Expression in a Rodent Model of Triple-Negative Breast Cancer

N-(2-羟基苯基)-2-丙基戊酰胺在三阴性乳腺癌啮齿动物模型中调节HDAC1和GPER1的表达

期刊:Biomedicines

影响因子:3.9

doi:10.3390/biomedicines14020322

Ramírez-Farías, Cynthia; Ventura-Juárez, Javier; Calvillo-Robledo, Argelia; Ávila-Blanco, Manuel Enrique; González-Blas, Daniel; Correa-Basurto, José; Quintanar Stephano, Andrés

GPER1 activation regulates renal purinergic P2Y(2) receptor natriuretic pathway

GPER1激活调节肾脏嘌呤能P2Y(2)受体利钠通路

期刊:American Journal of Physiology-Regulatory Integrative and Comparative Physiology

影响因子:2.3

doi:10.1152/ajpregu.00123.2025

Kulthinee, Supaporn; Nasci, Victoria L; Pollock, David M; Gohar, Eman Y

Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway.

GPER1 的过表达通过激活 cAMP 通路抑制食管癌的生长。

期刊:European Journal of Histochemistry

影响因子:2.1

doi:10.4081/ejh.2026.4422

Yin Hongmei, Han Xiumei, Zhang Qun, Li Duojie, Wang Fan

Deletion of Clock Gene Period1 (Per1) in Neurons but Not in Astrocytes Shortens Clock Period and Diminishes Light-Mediated Rapid Phase Advances in Mice.

神经元中时钟基因 Period1 (Per1) 的删除，但不会导致星形胶质细胞中时钟基因的删除，从而缩短小鼠的时钟周期并减少光介导的快速相位提前。

期刊:Clocks Sleep

影响因子:2.1

doi:10.3390/clockssleep8010009

Epuran Dan-Adrian, Albrecht Urs

Circadian regulators PER1 and PER2 regulate osteoclastogenesis by balancing competing activities of innate immunity genes

昼夜节律调节因子PER1和PER2通过平衡先天免疫基因的竞争活性来调节破骨细胞生成。

期刊:

影响因子:

doi:10.64898/2026.01.11.698889

Katoku-Kikyo, Nobuko; Vu, Elizabeth K; Mitchell, Samuel; Karkache, Ismael Y; Bradley, Elizabeth W; Kikyo, Nobuaki

Research progress on the role and mechanism of circadian clock gene PER1 in the occurrence and development of multiple diseases

昼夜节律基因PER1在多种疾病发生发展中的作用及机制的研究进展

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1715457

Zhao, Yuxiang; Li, Yujin; Lu, Tingting; Huang, Xinyue; Chen, Kerui; Tan, Lina; Gao, Lihua

PER1

发表日期：2025

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GPER1 reduces skin inflammation by inhibiting keratinocyte proliferation

GPER1通过抑制角质形成细胞增殖来减轻皮肤炎症。

Integrated Genomic and Transcriptomic Study Reveals MAPK11 and PER1 as Important Obesity Susceptibility Genes in a High-Risk Hispanic/Latino Population

整合基因组学和转录组学研究揭示 MAPK11 和 PER1 是高危西班牙裔/拉丁裔人群中重要的肥胖易感基因

GPER1 as a therapeutic target in MASLD: evidence for steatosis attenuation by agonist G1 in preclinical models.

GPER1 作为 MASLD 的治疗靶点：临床前模型中激动剂 G1 可减轻脂肪变性的证据。

Correction: AOH induces oxidative stress and DNA damage in ovarian cancer cells via modulation of GPER1 and HIF1α/PI3K/CLDNs signaling pathway

更正：AOH通过调节GPER1和HIF1α/PI3K/CLDNs信号通路诱导卵巢癌细胞氧化应激和DNA损伤

N-(2-Hydroxyphenyl)-2-propylpentanamide Modulates HDAC1 and GPER1 Expression in a Rodent Model of Triple-Negative Breast Cancer

N-(2-羟基苯基)-2-丙基戊酰胺在三阴性乳腺癌啮齿动物模型中调节HDAC1和GPER1的表达

GPER1 activation regulates renal purinergic P2Y(2) receptor natriuretic pathway

GPER1激活调节肾脏嘌呤能P2Y(2)受体利钠通路

Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway.

GPER1 的过表达通过激活 cAMP 通路抑制食管癌的生长。

Deletion of Clock Gene Period1 (Per1) in Neurons but Not in Astrocytes Shortens Clock Period and Diminishes Light-Mediated Rapid Phase Advances in Mice.

神经元中时钟基因 Period1 (Per1) 的删除，但不会导致星形胶质细胞中时钟基因的删除，从而缩短小鼠的时钟周期并减少光介导的快速相位提前。

Circadian regulators PER1 and PER2 regulate osteoclastogenesis by balancing competing activities of innate immunity genes

昼夜节律调节因子PER1和PER2通过平衡先天免疫基因的竞争活性来调节破骨细胞生成。

Research progress on the role and mechanism of circadian clock gene PER1 in the occurrence and development of multiple diseases

昼夜节律基因PER1在多种疾病发生发展中的作用及机制的研究进展