日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2-Mediated Mitochondrial Stabilization

巨噬细胞TRIM21抑制通过PHB2介导的线粒体稳定作用改善小鼠急性胰腺炎

Xu, Yansong; Sun, Yuansong; Zhou, Xin; Song, Kai; Yin, Chunlin; Wang, Zhaohua; Xie, Fei; Li, He

Upregulation of PPTC7 in brain microvascular endothelial cell aggravates diabetic cognitive dysfunction by impairing PHB2 mediated mitochondrial function.

脑微血管内皮细胞中 PPTC7 的上调会损害 PHB2 介导的线粒体功能,从而加剧糖尿病认知功能障碍。

Yang Fan, Pang Pengcheng, Yang Kang, Niu Xinyu, Cheng Fang, Li Wei

PHB2 ameliorates ferroptosis and aortic aneurysm/dissection through NEDD4L-dependent ubiquitination of NCOA4.

PHB2 通过 NEDD4L 依赖的 NCOA4 泛素化来改善铁死亡和主动脉瘤/夹层。

Xiong Shengjun, Lin Jie, An Ying, Du Yuxin, Li Yiran E, Du Zunhui, Zou Rongjun, Abudureyimu Miyesaier, Ge Junbo, Zhang Yingmei, Ren Jun

Src-mediated PHB2 phosphorylation disrupts mitochondrial cristae through cardiolipin dissociation in hepatocellular carcinoma.

在肝细胞癌中,Src 介导的 PHB2 磷酸化通过心磷脂解离破坏线粒体嵴。

Development of capsaicin-derived prohibitin ligands to modulate the Aurora kinase A/PHB2 interaction and mitophagy in cancer cells

开发辣椒素衍生的抑制配体以调节癌细胞中Aurora激酶A/PHB2相互作用和线粒体自噬

Amel Djehal #,Claire Caron #,Deborah Giordano,Valentina Pizza,Kimberley Farin,Angelo Facchiano,Laurent Désaubry,Giulia Bertolin

PHB2 mitigates intervertebral disc degeneration by modulating mitophagy to inhibit necroptosis in nucleus pulposus cells.

PHB2 通过调节线粒体自噬来抑制髓核细胞的坏死性凋亡,从而减轻椎间盘退变。

LECT2-PHB2 axis: a new mechanistic insight and therapeutic opportunity in alcohol-associated hepatitis

LECT2-PHB2轴:酒精相关性肝炎的新机制见解和治疗契机

Li, Hui; Song, Meiyi; Hylemon, Phillip B; Zhou, Huiping

Efficient PHB2 (prohibitin 2) exposure during mitophagy depends on VDAC1 (voltage dependent anion channel 1).

线粒体自噬过程中 PHB2(抑制蛋白 2)的有效暴露依赖于 VDAC1(电压依赖性阴离子通道 1)。

Aldehyde Dehydrogenase 2 Lactylation Aggravates Mitochondrial Dysfunction by Disrupting PHB2 Mediated Mitophagy in Acute Kidney Injury

醛脱氢酶2乳化作用通过破坏PHB2介导的线粒体自噬加剧急性肾损伤中的线粒体功能障碍

Li, Jiaying; Shi, Xiaoxiao; Xu, Jiatong; Wang, Kaiyue; Hou, Fangxing; Luan, Xiaodong; Chen, Limeng

Targeting EPHB2/ABL1 restores antitumor immunity in preclinical models of ependymoma

靶向 EPHB2/ABL1 可恢复室管膜瘤临床前模型中的抗肿瘤免疫力

Ren, Jun; Amoozgar, Zohreh; Uccello, Taylor P; Lei, Pin-Ji; Zhao, Yuhui; Ho, William W; Huang, Peigen; Kardian, Alisha; Mack, Stephen C; Duda, Dan G; Xu, Lei; Jain, Rakesh K