日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Live-cell imaging reveals decreased cAMP in a PFE-associated c.1050-3C>G PTH1R cell model

活细胞成像显示,在 PFE 相关 c.1050-3C>G PTH1R 细胞模型中 cAMP 水平降低

Marnet, K; Subramanian, H; Wiesler, M; Borst, A; Liedtke, D; Pattappa, G; Docheva, D; Nikolaev, V O; Stellzig-Eisenhauer, A; Eigenthaler, M; Herrmann, M

Genetic Determinants of Primary Failure of Eruption: A Comprehensive Review of PTH1R Variants

原发性皮疹消退失败的遗传决定因素:PTH1R变异体的全面综述

Niccolini, Benedetta; Lauretti, Giulia; Chiurazzi, Pietro; Grippaudo, Cristina; Tabolacci, Elisabetta

Upregulation of Parathyroid Hormone Receptor 1 (PTH1R) in Non-Mechanostimulated Osteocytes Under High-Glucose Conditions Promotes a Macrophage Pro-Inflammatory and Osteoclastogenic Phenotype via IL-6 Secretion

高糖条件下非机械刺激骨细胞中甲状旁腺激素受体1(PTH1R)的上调通过IL-6分泌促进巨噬细胞的促炎和破骨细胞生成表型

Irene Tirado-Cabrera,Joan Pizarro-Gomez,Eduardo Martin-Guerrero,Celia Méndez-Rodríguez,Teresita Bellido,Arancha R Gortazar,Juan A Ardura

Insights into G-protein coupling preference from cryo-EM structures of G(q)-bound PTH1R.

从 G(q) 结合的 PTH1R 的冷冻电镜结构中了解 G 蛋白偶联偏好。

Sano Fumiya K, Shimizume Kota, Kobayashi Kazuhiro, Awazu Toshikuni, Kawakami Kouki, Akasaka Hiroaki, Kobayashi Takaaki A, Tanaka Tatsuki, Okamoto Hiroyuki H, Hirano Hisato, Kusakizako Tsukasa, Shihoya Wataru, Kise Yoshiaki, Itoh Yuzuru, Ishitani Ryuichiro, Okada Yasushi, Sako Yasushi, Yanagawa Masataka, Inoue Asuka, Nureki Osamu

A novel PTH1R mutation causes primary failure of eruption via the cAMP-PI3K/AKT pathway

一种新的PTH1R突变通过cAMP-PI3K/AKT通路导致原发性皮疹形成障碍。

Lu, Kejie; Qian, Ying; Gong, Jiaxing; Li, Zhiyong; Yu, Mengfei; Wang, Huiming

Human diseases caused by homozygous PTH1R mutations

由PTH1R纯合突变引起的人类疾病

Portales-Castillo, Ignacio; Höppner, Jakob; Jüppner, Harald; Gardella, Thomas J

Kidney organoids demonstrate that PTH1R drives a cystogenic cAMP-pPKA-pCREB axis in developmental polycystic kidney disease

肾脏类器官研究表明,PTH1R 在发育性多囊肾病中驱动囊肿形成 cAMP-pPKA-pCREB 轴。

Humayra Afrin ,Jielu Hao Robichaud ,Usama Qamar ,Peter C Harris ,Navin Gupta

Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants

骨架修饰提供了一种长效的致病性、组成型活性 PTH1R 变体的反向激动剂

Liu, Shi; Daley, Eileen J; Tran, Lauren My-Linh; Yu, Zhen; Reyes, Monica; Dean, Thomas; Khatri, Ashok; Levine, Paul M; Balana, Aaron T; Pratt, Matthew R; Jüppner, Harald; Gellman, Samuel H; Gardella, Thomas J

Parathyroid hormone-PTH1R signaling in cardiovascular disease and homeostasis

甲状旁腺激素-PTH1R信号通路在心血管疾病和体内平衡中的作用

Towler, Dwight A

Negative feedback between PTH1R and IGF1 through the Hedgehog pathway in mediating craniofacial bone remodeling

PTH1R与IGF1通过Hedgehog信号通路之间的负反馈调节颅面骨重塑

Yi Fan,Ping Lyu,Jiahe Wang,Yali Wei,Zucen Li,Shiwen Zhang,Takehito Ouchi,Junjun Jing,Quan Yuan,Clifford J Rosen,Chenchen Zhou