Targeting NRAS via miR-1304-5p or farnesyltransferase inhibition confers sensitivity to ALK inhibitors in ALK-mutant neuroblastoma
通过 miR-1304-5p 或法尼基转移酶抑制靶向 NRAS 可使 ALK 突变型神经母细胞瘤对 ALK 抑制剂敏感。
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-024-47771-x
Perla Pucci ,Liam C Lee ,Miaojun Han ,Jamie D Matthews ,Leila Jahangiri ,Michaela Schlederer ,Eleanor Manners ,Annabel Sorby-Adams ,Joshua Kaggie ,Ricky M Trigg ,Christopher Steel ,Lucy Hare ,Emily R James ,Nina Prokoph ,Stephen P Ducray ,Olaf Merkel ,Firkret Rifatbegovic ,Ji Luo ,Sabine Taschner-Mandl ,Lukas Kenner ,G A Amos Burke ,Suzanne D Turner