日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Molecular basis for the activation of Aurora A and Plk1 kinases during mitotic entry.

有丝分裂开始时 Aurora A 和 Plk1 激酶激活的分子基础。

Pillan Anaïs, Ormancey Philippine, Ben Choug Celia, Orlicky Stephen, Tavernier Nicolas, Van Hove Lucie, Ossareh-Nazari Batool, Joly Nicolas, Sicheri Frank, Lorca Thierry, Pintard Lionel

Unhooking the Hook: Optimization of the Aurora A Targeting PROTAC JB170 to CCT400028, an In Vitro Degrader Chemical Probe

解开钩子:优化 Aurora A 靶向 PROTAC JB170 至 CCT400028,一种体外降解化学探针

O'Hanlon, Jack A; Gutsche, Katrin; Müller, Juliane Elisabeth; Ranjan Prusty, Nihar; Mirza, Amin; Roumeliotis, Theodoros I; Yang, Hengzhang; Stubbs, Mark; Hallett, Stephen T; Eing, Lorenz; McAndrew, Peter Craig; Choudhary, Jyoti Sharma; Le Bihan, Yann-Vaï; Caldwell, John; van Montfort, Rob L M; Workman, Paul; Wolf, Elmar; Newton, Gary K; Evans, Lindsay E

High-throughput discovery and characterisation of pentafluorobenzene sulfonamide modifiers of Aurora A kinase

利用高通量方法发现和表征Aurora A激酶的五氟苯磺酰胺修饰剂

Chesti, Julian; Miles, Jennifer A; Collins, Lawrence J; McCallum, Hamish A; Foglizzo, Martina; Ahangar, Mohd Syed; Zeqiraj, Elton; Bayliss, Richard; Warriner, Stuart L; Wright, Megan H; Nelson, Adam

Aurora A binds to the transactivation domain of c-Myc and recognizes the phosphorylated N-terminal degron motif

Aurora A 与 c-Myc 的转录激活结构域结合,并识别磷酸化的 N 端降解基序。

Joshi, Nidhi; Dunleavy, Katie M; Beel, Kaitlin M; Engel, Tiffany A; Thompson, Andrew R; John, Felix L; Thomas, David D; Levinson, Nicholas M

TP-0903 Suppresses Aurora A-PLK1 Signaling to Inhibit Proliferation of a Myelodysplastic Syndrome-Derived Cell Line

TP-0903抑制Aurora A-PLK1信号通路以抑制骨髓增生异常综合征衍生细胞系的增殖

Kimura-Hyoda, Tomoko; Ryu, Mikuri; Yuta, Ryosuke; Fukumoto, Saori; Hosokawa, Kentaro; Yao, Hisayuki; Yasuda, Yoko; Miura, Koichi; Tohyama, Kaoru; Arai, Fumio; Uchiumi, Takeshi

Discovery of a Potent and Highly Selective Inhibitor of Aurora A Kinase

发现一种高效且高选择性的Aurora A激酶抑制剂

Long, Liang; Zhai, Hongjin; Zhang, Bin; Zhu, Chengchen; Deng, Xiaoyi; Chan, Albert S C; Liu, Quentin; Lu, Gui

Synergistic effects of Aurora A and AKT inhibitors combined with radiation in colon cancer cells

Aurora A 和 AKT 抑制剂联合放射治疗对结肠癌细胞具有协同作用

Peng, Qiuxia; Zhou, Wei; Li, Jie; Liu, Danqing

Synergistic inhibition of colorectal cancer progression by silencing Aurora A and the targeting protein for Xklp2

通过沉默 Aurora A 和靶向 Xklp2 蛋白,协同抑制结直肠癌进展

Gui-Xian Sheng ,Yu-Jia Zhang ,Tao Shang

Targeting Aurora A to Overcome Cisplatin Resistance in Head and Neck Cancer

靶向 Aurora A 以克服头颈癌的顺铂耐药性

Li, X; Wang, Z; Oakley, G G; Wang, L; Lanzel, E A; Buchakjian, M R; Peng, A

A chromatin-associated pool of Aurora A controls kinetochore-microtubule attachments to ensure chromosome biorientation

染色质相关的Aurora A蛋白池控制着动粒-微管连接,以确保染色体的双向定向。

Meaders, Johnathan L; Rodriguez, Alyssa A; Variyar, Smriti; Park, SungWoo; Cirulli, Alessandro E; Oegema, Karen; Corbett, Kevin D; Desai, Arshad