QPCT相关文献与解析，生知库 | 链接生命科学的每一步

Smid, Hannah Elaine; Colotti, Jana; Nölp, Sophia; Arlt, Nike Sophia; Weber, Sophie; Gumann, Amelie; von Hörsten, Stephan; Karow, Axel; Schuh, Wolfgang

QPCT

免疫/内分泌

发表日期：2026

文献求助收藏

Novel Piperidinylphenylcarbonitrile Derivatives as QPCT and QPCTL Inhibitors for Treating Cancer

新型哌啶基苯基腈衍生物作为QPCT和QPCTL抑制剂用于癌症治疗

期刊:ACS Medicinal Chemistry Letters

影响因子:4

doi:10.1021/acsmedchemlett.5c00583

Fedratinib inhibits ovarian cancer progression by downregulating QPCT expression

Fedratinib通过下调QPCT表达抑制卵巢癌进展

期刊:Discover Oncology

影响因子:2.8

doi:10.1007/s12672-025-03734-2.

Ying Dong,Yue Deng,Longyan Zhu,Rongji Li,Huilin Yang,Lihua Yang

Novel Phenylpiperidine Derivatives as QPCT and QPCTL Inhibitors for Treating Cancer or Fibrotic Diseases

新型苯基哌啶衍生物作为QPCT和QPCTL抑制剂用于治疗癌症或纤维化疾病

期刊:ACS Medicinal Chemistry Letters

影响因子:4

doi:10.1021/acsmedchemlett.4c00495

Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy

开发一种强效的基于苯甲腈的谷氨酰肽环转移酶样蛋白（QPCTL）抑制剂，具有抗肿瘤功效

期刊:Signal Transduction and Targeted Therapy

影响因子:52.7

doi:10.1038/s41392-023-01715-x

Yu, Lei; Zhao, Pengcheng; Sun, Yaoliang; Zheng, Zening; Du, Wenhao; Zhang, Lishan; Li, Yaxu; Xie, Longyan; Xu, Shilin; Wang, Ping

Deciphering the role of QPCTL in glioma progression and cancer immunotherapy

阐明QPCTL在胶质瘤进展和癌症免疫治疗中的作用

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2023.1166377

Liu, Yu'e; Lu, Shaojuan; Sun, Yihong; Wang, Fei; Yu, Shibo; Chen, Xi; Wu, Lei-Lei; Yang, Hui; Shi, Yufeng; Zhao, Kaijun

QPCT regulation by CTCF leads to sunitinib resistance in renal cell carcinoma by promoting angiogenesis

CTCF 调控 QPCT 促进血管生成，导致肾细胞癌产生舒尼替尼耐药

期刊:International Journal of Oncology

影响因子:4.5

doi:10.3892/ijo.2021.5228

Tangliang Zhao #, Yulin Zhou #, Qingyun Wang #, Xiaoming Yi, Silun Ge, Haowei He, Song Xue, Bowen Du, Jingping Ge, Jie Dong, Le Qu, Linhui Wang, Wenquan Zhou

DNA methylation-regulated QPCT promotes sunitinib resistance by increasing HRAS stability in renal cell carcinoma

DNA 甲基化调节的 QPCT 通过增加肾细胞癌中的 HRAS 稳定性来促进舒尼替尼耐药性

期刊:Theranostics

影响因子:12.4

doi:10.7150/thno.35572

Tangliang Zhao, Yi Bao, Xinxin Gan, Jie Wang, Qiong Chen, Zhihui Dai, Bing Liu, Anbang Wang, Shuhan Sun, Fu Yang, Linhui Wang

Immunomodulatory functions of glutaminyl cyclases QPCTL and QPCT

谷氨酰环化酶QPCTL和QPCT的免疫调节功能

Novel Piperidinylphenylcarbonitrile Derivatives as QPCT and QPCTL Inhibitors for Treating Cancer

新型哌啶基苯基腈衍生物作为QPCT和QPCTL抑制剂用于癌症治疗

Fedratinib inhibits ovarian cancer progression by downregulating QPCT expression

Fedratinib通过下调QPCT表达抑制卵巢癌进展

Novel Phenylpiperidine Derivatives as QPCT and QPCTL Inhibitors for Treating Cancer or Fibrotic Diseases

新型苯基哌啶衍生物作为QPCT和QPCTL抑制剂用于治疗癌症或纤维化疾病

Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy

开发一种强效的基于苯甲腈的谷氨酰肽环转移酶样蛋白（QPCTL）抑制剂，具有抗肿瘤功效

Deciphering the role of QPCTL in glioma progression and cancer immunotherapy

阐明QPCTL在胶质瘤进展和癌症免疫治疗中的作用

QPCT regulation by CTCF leads to sunitinib resistance in renal cell carcinoma by promoting angiogenesis

CTCF 调控 QPCT 促进血管生成，导致肾细胞癌产生舒尼替尼耐药

DNA methylation-regulated QPCT promotes sunitinib resistance by increasing HRAS stability in renal cell carcinoma

DNA 甲基化调节的 QPCT 通过增加肾细胞癌中的 HRAS 稳定性来促进舒尼替尼耐药性