日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A missing piece of the puzzle in pulmonary fibrosis: anoikis resistance promotes fibroblast activation

肺纤维化难题中缺失的一块:抗细胞凋亡促进成纤维细胞活化

Juan Yin #, Jing Wang #, Xinxin Zhang #, Yan Liao #, Wei Luo, Sha Wang, Jiawei Ding, Jie Huang, Mengling Chen, Wei Wang, Shencun Fang, Jie Chao

Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex

mTOR抑制剂对促生存蛋白的相互影响决定了结节性硬化症的治疗反应。

Molly C McNamara ,Aaron M Hosios ,Margaret E Torrence ,Ting Zhao ,Cameron Fraser ,Meghan Wilkinson ,David J Kwiatkowski ,Elizabeth P Henske ,Chin-Lee Wu ,Kristopher A Sarosiek ,Alexander J Valvezan ,Brendan D Manning

M2I-1 disrupts the in vivo interaction between CDC20 and MAD2 and increases the sensitivities of cancer cell lines to anti-mitotic drugs via MCL-1s

M2I-1 破坏 CDC20 和 MAD2 之间的体内相互作用,并通过 MCL-1 增加癌细胞系对抗有丝分裂药物的敏感性

Jianquan Li, Nanmao Dang, Nuria Martinez-Lopez, Paul A Jowsey, Dong Huang, Robert N Lightowlers, Fei Gao, Jun-Yong Huang

Anthelmintic pyrvinium pamoate blocks Wnt/β-catenin and induces apoptosis in multiple myeloma cells

驱虫药吡维尼铵帕莫酸盐阻断 Wnt/β-catenin 并诱导多发性骨髓瘤细胞凋亡

Fang Xu, Yingjie Zhu, Yuhong Lu, Zhi Yu, Jun Zhong, Yangqiu Li, Jingxuan Pan

Mitochondrial Bcl-2 family dynamics define therapy response and resistance in neuroblastoma

线粒体 Bcl-2 家族动态决定神经母细胞瘤的治疗反应和耐药性

Kelly C Goldsmith, Michelle Gross, Susan Peirce, Dema Luyindula, Xueyuan Liu, Annette Vu, Michael Sliozberg, Rong Guo, Huaqing Zhao, C Patrick Reynolds, Michael D Hogarty

The MEK-ERK pathway negatively regulates bim expression through the 3' UTR in sympathetic neurons

MEK-ERK 通路通过交感神经元中的 3' UTR 负向调节 bim 表达

Rosie Hughes, Jonathan Gilley, Mark Kristiansen, Jonathan Ham

The proapoptotic dp5 gene is a direct target of the MLK-JNK-c-Jun pathway in sympathetic neurons

促凋亡的 dp5 基因是交感神经元中 MLK-JNK-c-Jun 通路的直接靶标

Emily Towers, Jonathan Gilley, Rebecca Randall, Rosie Hughes, Mark Kristiansen, Jonathan Ham