HUWE1 stimulates mTORC1 activity by enhancing Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis
HUWE1通过增强Rheb与mTORC1的相互作用来刺激mTORC1活性，并支持嘧啶从头合成。
期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2025.116382.
Takayuki Ikeda,Sungki Hong,Shota Yoshida,Swayam Prakash Srivastava,Abhiram Kunamneni,Yao Yao,Om Khuperkar,Venkatesha Basrur,Henry Kuang,Maureen Kachman,Abraham Raskind,Heidi Baum,Arya Joshi,Vinamra Swaroop,Aaron Thurman,Oliviamae Kopasz-Gemmen,Siddharth Kandukuri,F N U Pradeepa,Hideto Yonekura,Jiandie D Lin,Ken Inoki
