RIPK2相关文献与解析，生知库 | 链接生命科学的每一步

LncRNA SBF2-AS1 Regulates Pyroptosis to Promote Chlamydia trachomatis Growth Through miR-196b-5p/RIPK2 Axis.

LncRNA SBF2-AS1 通过 miR-196b-5p/RIPK2 轴调节细胞焦亡以促进沙眼衣原体生长。

期刊:Microorganisms

影响因子:4.2

doi:10.3390/microorganisms14020459

Wu Hongrong, Cheng Shan, Yang Yewei, Lei Wenbo, Zhou Yu, Li Zhongyu

XIAP down-regulation inhibits RIPK2 ubiquitination-mediated insulin resistance.

XIAP 下调抑制 RIPK2 泛素化介导的胰岛素抵抗。

期刊:Endocrine Connections

影响因子:2.8

doi:10.1530/EC-25-0429

Zhao Chunnan, Zhang Zezhi, Li Ran, Geng Xueli

RIPK2 induces docetaxel resistance in prostate cancer through the NF-κB/P-gp signaling pathway

RIPK2通过NF-κB/P-gp信号通路诱导前列腺癌细胞对多西他赛产生耐药性

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0341445

Xing, Shaoqiang; Xu, Zhaoliang; Zeng, Sheng; Yue, Minghao; Xing, Wenzhou; Liu, Qian

A transformer-based strategy to develop RP20 as a potent RIPK2 inhibitor for acetaminophen-induced acute liver injury

基于Transformer的策略开发RP20，使其成为治疗对乙酰氨基酚引起的急性肝损伤的有效RIPK2抑制剂。

期刊:Acta Pharmaceutica Sinica B

影响因子:14.6

doi:10.1016/j.apsb.2025.06.003

DUBA sustains the stability of NOD2 and RIPK2 to enhance innate immune responses

DUBA 维持 NOD2 和 RIPK2 的稳定性，从而增强先天免疫反应

期刊:Cell Death and Differentiation

影响因子:13.7

doi:10.1038/s41418-025-01516-5

Bincheng Zhou ，Maojin Yin ，Xian Su ，Suhui Sheng ，Xue Du ，Jiangyun Shen ，Kangmin Chen ，Deqi Wang ，Zhenhu Zhu ，Yanqi Xu ，Zhongding Li ，Jianmin Li ，Yuhua Li ，Jing Ruan ，Xu Wang

Dual-backbone pectic polysaccharide activates NOD1/RIPK2/NF-κB and mitochondrial metabolism to enhance the immune activity of macrophages

双骨架果胶多糖激活NOD1/RIPK2/NF-κB和线粒体代谢，从而增强巨噬细胞的免疫活性。

期刊:npj Science of Food

影响因子:7.8

doi:10.1038/s41538-025-00570-0

Liu, Ziwei; Li, Hangyu; Yang, Shuyao; Zhang, Xinnan; Liu, Qianqian; Xu, Yuan; Yang, Yanwen; Liao, Yi; Wang, Yao; Feng, Haibo

Correction: N4BP3 facilitates NOD2-MAPK/NF-κB pathway in inflammatory bowel disease through mediating K63-linked RIPK2 ubiquitination

更正：N4BP3 通过介导 K63 连接的 RIPK2 泛素化来促进炎症性肠病中的 NOD2-MAPK/NF-κB 通路。

期刊:Cell Death Discovery

影响因子:7

doi:10.1038/s41420-025-02574-x

Jiang, Wang; Zhao, Yan; Han, Min; Xu, Jiafan; Chen, Kun; Liang, Yi; Yin, Jie; Hu, Jinyue; Shen, Yueming

Fusobacterium nucleatum promotes anastomotic leakage by activating epithelial cells through the NOD1/RIPK2/ERK signalling pathway to drive IL-1β-induced neutrophil chemotaxis and collagen degradation

具核梭杆菌通过激活NOD1/RIPK2/ERK信号通路激活上皮细胞，进而促进IL-1β诱导的中性粒细胞趋化和胶原蛋白降解，从而促进吻合口渗漏。

期刊:Clinical and Translational Medicine

影响因子:6.8

doi:10.1002/ctm2.70262

Wei, Zixian; Bao, Liqing; Li, Bowen; Yang, Jinhua; Wang, Jijiao; Xu, Fangqi; Wenren, Hubin; Zhang, Kunyu; Shi, Shang; Yan, Liying; Tao, Xin; Zhang, Tianqi; Wang, Zhiyue; Liu, Yang

Effect of Nano-Gefitinib on Solid Ehrlich Carcinoma via Targeting EGFR, RIPK2 Pathways, and Macrophage Reprogramming

纳米吉非替尼通过靶向EGFR、RIPK2通路和巨噬细胞重编程对实体艾氏癌的影响

期刊:Pharmaceuticals

影响因子:4.8

doi:10.3390/ph18111747

Ashoura, Neveen R; Saad, Hebatallah M; El Zahaby, Enas I; Salama, Alyaa R; Amer, Nihal E; Elhussieny, Omnya; Edres, Hanan A; Nematalla, Hisham A; Mohammed, Salman A A

Peripheral RIPK2 degradation improves neurological outcomes after experimental ischemic stroke.

外周 RIPK2 降解可改善实验性缺血性中风后的神经功能预后。

LncRNA SBF2-AS1 Regulates Pyroptosis to Promote Chlamydia trachomatis Growth Through miR-196b-5p/RIPK2 Axis.

LncRNA SBF2-AS1 通过 miR-196b-5p/RIPK2 轴调节细胞焦亡以促进沙眼衣原体生长。

XIAP down-regulation inhibits RIPK2 ubiquitination-mediated insulin resistance.

XIAP 下调抑制 RIPK2 泛素化介导的胰岛素抵抗。

RIPK2 induces docetaxel resistance in prostate cancer through the NF-κB/P-gp signaling pathway

RIPK2通过NF-κB/P-gp信号通路诱导前列腺癌细胞对多西他赛产生耐药性

A transformer-based strategy to develop RP20 as a potent RIPK2 inhibitor for acetaminophen-induced acute liver injury

基于Transformer的策略开发RP20，使其成为治疗对乙酰氨基酚引起的急性肝损伤的有效RIPK2抑制剂。

DUBA sustains the stability of NOD2 and RIPK2 to enhance innate immune responses

DUBA 维持 NOD2 和 RIPK2 的稳定性，从而增强先天免疫反应

Dual-backbone pectic polysaccharide activates NOD1/RIPK2/NF-κB and mitochondrial metabolism to enhance the immune activity of macrophages

双骨架果胶多糖激活NOD1/RIPK2/NF-κB和线粒体代谢，从而增强巨噬细胞的免疫活性。

Correction: N4BP3 facilitates NOD2-MAPK/NF-κB pathway in inflammatory bowel disease through mediating K63-linked RIPK2 ubiquitination

更正：N4BP3 通过介导 K63 连接的 RIPK2 泛素化来促进炎症性肠病中的 NOD2-MAPK/NF-κB 通路。

Fusobacterium nucleatum promotes anastomotic leakage by activating epithelial cells through the NOD1/RIPK2/ERK signalling pathway to drive IL-1β-induced neutrophil chemotaxis and collagen degradation

具核梭杆菌通过激活NOD1/RIPK2/ERK信号通路激活上皮细胞，进而促进IL-1β诱导的中性粒细胞趋化和胶原蛋白降解，从而促进吻合口渗漏。

Effect of Nano-Gefitinib on Solid Ehrlich Carcinoma via Targeting EGFR, RIPK2 Pathways, and Macrophage Reprogramming

纳米吉非替尼通过靶向EGFR、RIPK2通路和巨噬细胞重编程对实体艾氏癌的影响