日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Tucidinostat Plus R-CHOP vs R-CHOP in MYC/BCL2 Double-Expressor Diffuse Large B-Cell Lymphoma: A Randomized Clinical Trial

Tucidinostat Plus R-CHOP vs R-CHOP 治疗 MYC/BCL2 双表达弥漫性大 B 细胞淋巴瘤：一项随机临床试验

期刊:Journal of the American Medical Association
影响因子:55
doi:10.1001/jama.2026.4199
Xu, Peng-Peng; Song, Yu-Qin; Shen, Jian-Zhen; Cai, Qing-Qing; Zhou, Hui; Zhang, Li-Ling; Xiang, Ying; Sun, Xiu-Hua; Yang, Wei; Yao, Zhi-Hua; Jing, Hong-Mei; Wen, Shu-Juan; Jin, Jie; Xue, Hong-Wei; Cen, Hong; Ding, Kai-Yang; Jin, Zheng-Ming; Liu, Li-Hong; Xing, Xiao-Jing; Li, Lan-Fang; Hou, Ming; Liu, Lin; Zhang, Ming-Zhi; Li, Wen-Yu; Bai, Ou; Feng, Ru; Zhu, Zun-Min; Wu, Hui-Jing; Su, Li-Ping; Gao, Li; Li, Fei; Huang, Wen-Rong; Liu, Peng; Yan, Xiao-Jing; Zhao, Ying; Su, Hang; Zhao, Xie-Lan; Fu, Rong; Liu, Hong; Shi, Wen-Yu; Li, Hui-Zhi; Chen, Bo; Ning, Zhi-Qiang; Zhu, Jun; Zhao, Wei-Li
T细胞
MYC
CHOP
BCL2
HOP
淋巴瘤
细胞生物学
发表日期：2026
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Multiselective RAS(ON) inhibition targets oncogenic RAS and overcomes RAS-mediated resistance to FLT3i and BCL2i in AML

多选择性 RAS(ON) 抑制剂靶向致癌 RAS，并克服急性髓系白血病 (AML) 中 RAS 介导的对 FLT3 抑制剂和 BCL2 抑制剂的耐药性。

期刊:Blood
影响因子:23.1
doi:10.1182/blood.2025030558
Popescu, Bogdan; Jones, Matthew F; Piao, Madison; Tran, Elaine; Koh, Andrew; Lomeli, Isabelle; Peretz, Cheryl A C; Murad, Natalia; Abelson, Sydney; Morales, Carolina; Rivera, Jose M; Batingana, Alexa Rane; D'Souza, Jeevitha; Pikman, Yana; Cheng, Michael L; Logan, Aaron C; Huang, Benjamin J; Stieglitz, Elliot; Smith, Catherine C
FLT3
RAS
BCL2
白血病
肿瘤
肿瘤免疫
发表日期：2026
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DNA secondary structures in BCL2 and MYC elicit activation-induced cytidine deaminase binding and activity.

BCL2 和 MYC 中的 DNA 二级结构可引起活化诱导的胞苷脱氨酶结合和活性。

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkag203
McCrury Mason, Sanchez Ambrocio, Mangold Rylie, Spears Todd J, Doshier Claire, Buisson Rémi, Miah Mojnu, Akdeniz Derin, Kendrick Samantha
MYC
BCL2
发表日期：2026
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Machine learning prioritization of antibiotic residues in aquatic foods reveals exposure-driven genotoxic risk mediated by BCL2

利用机器学习对水产食品中抗生素残留进行优先级排序，揭示了由 BCL2 介导的暴露驱动型基因毒性风险。

期刊:Food Chemistry-X
影响因子:8.2
doi:10.1016/j.fochx.2026.103646
Zhu, Huangqu; Zhou, Kaili; Li, Yuanzhi; Zhou, Qingqiong; Peng, Mingjun; Wu, Xinlan; Mao, Xinwu; Yang, Qiaoyuan
BCL2
毒理研究
发表日期：2026
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Population-wide introduction of dose-adjusted EPOCH-R in high-grade B-cell lymphoma with MYC/BCL2 rearrangements, DLBCL morphology

在具有 MYC/BCL2 重排的高级别 B 细胞淋巴瘤、DLBCL 形态学中，广泛推广剂量调整后的 EPOCH-R 方案

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2025017282
Alduaij, Waleed; Sehn, Laurie H; Champagne, Jean-Nicolas; Collinge, Brett; Ben-Neriah, Susana; Jiang, Aixiang; Hilton, Laura K; Boyle, Merrill; Meissner, Barbara; Slack, Graham W; Farinha, Pedro; Craig, Jeffrey W; Savage, Kerry J; Villa, Diego; Gerrie, Alina S; Freeman, Ciara L; Mungall, Andrew J; Steidl, Christian; Scott, David W
T细胞
淋巴瘤
EPO
BCL2
细胞生物学
MYC
发表日期：2026
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HDAC3 inhibition as a therapeutic strategy in T-cell acute lymphoblastic leukemia via the TYK2-STAT1-BCL2 signaling pathway

通过TYK2-STAT1-BCL2信号通路抑制HDAC3作为T细胞急性淋巴细胞白血病的一种治疗策略

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2026.1752727
Gu, Zhenyang; Liu, Yuchen; Jiao, Yifan; Wang, Hao; Wang, Lili; Le, Ning; Zhang, Xiawei; Liu, Qingyang; Xu, Yang; Liu, Daihong; Gao, Chunji; Dou, Liping
STAT1
T细胞
JAK/STAT
信号转导
HDAC3
白血病
T细胞
BCL2
细胞生物学
免疫/内分泌
发表日期：2026
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Dissecting tumor heterogeneity in colorectal cancer: uncovering the role of BCL2L1(+) cells through single-cell analysis

通过单细胞分析解析结直肠癌的肿瘤异质性：揭示BCL2L1(+)细胞的作用

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2026.1742767
Zhu, Guangsheng; Liu, Ya; Shi, Yunxuan; Qian, Nuan; Song, Chengcheng; Liu, Xu; Xiahou, Zhikai; Xiong, Zhiguo; Hu, Junjie
肿瘤
肠癌
肿瘤免疫
BCL2
细胞生物学
肿瘤异质性
单细胞
发表日期：2026
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Clinicopathological and transcriptomic profiles of 101 patients with diffuse large B-cell lymphoma/high-grade B-cell lymphoma with double-hit MYC and BCL2 or BCL6 and triple hit

对101例伴有MYC和BCL2或BCL6双重打击以及三重打击的弥漫性大B细胞淋巴瘤/高级别B细胞淋巴瘤患者的临床病理学和转录组学特征进行分析

期刊:Histopathology
影响因子:4.1
doi:10.1111/his.70117
Miyaoka, Masashi; Carreras, Joaquim; Kikuti, Yara Yukie; Ikoma, Haruka; Nagase, Shunsuke; Ito, Atsushi; Orita, Makoto; Kawada, Hiroshi; Sakai, Rika; Sato, Yasuharu; Nishimura, Midori Filiz; Tsukasaki, Kunihiro; Momose, Shuji; Kameoka, Yoshihiro; Yoshida, Masahiro; Satou, Akira; Kato, Seiichi; Oishi, Naoki; Saito, Akio; Sadahira, Ken; Masugi, Yohei; Nakamura, Naoya
淋巴瘤
MYC
BCL6
B细胞
免疫/内分泌
细胞生物学
BCL2
发表日期：2026
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Human amnion epithelial cell-derived exosomal miR-25-3p enhances mucin expression in conjunctival goblet cells via downregulating BCL2L11.

人羊膜上皮细胞来源的外泌体 miR-25-3p 通过下调 BCL2L11 来增强结膜杯状细胞中粘蛋白的表达。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-37794-3
Zhang Yanming, Wu Wenjia, Meng Ting, Yang Shuiping, Miao Gong
Human
细胞生物学
上皮细胞
BCL2
外泌体
发表日期：2026
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Combinatorial targeting of MYC/BCL2-associated vulnerabilities in high-grade B-cell lymphoma

针对高级别B细胞淋巴瘤中MYC/BCL2相关脆弱性的组合靶向治疗

期刊:British Journal of Haematology
影响因子:3.8
doi:10.1111/bjh.70249
Donati, Giulio; Nicoli, Paola; Miele, Federica; Podini, Paola; Dina, Giorgia; Quattrini, Angelo; Amati, Bruno
B细胞
淋巴瘤
BCL2
细胞生物学
MYC
免疫/内分泌
发表日期：2026
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