日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Carba-NAD binding activates SIR2 by reshaping conformational plasticity and rewiring long-range allosteric networks

Carba-NAD 结合通过重塑构象可塑性和重组长程变构网络来激活 SIR2。

Zhang, Bao-Dan; Zhao, De-Rui; Liu, Meng-Ting; Yang, Li-Quan; Sang, Peng

Genome-wide identification and multi-dimensional functional characterization of the SIR2 family in Brassica napus L.

甘蓝型油菜中 SIR2 家族的全基因组鉴定和多维功能表征。

Mechanistic basis for the allosteric activation of NADase activity in the Sir2-HerA antiphage defense system.

Sir2-HerA 抗噬菌体防御系统中 NADase 活性变构激活的机制基础。

Betulinic Acid Increases the Lifespan of Drosophila melanogaster via Sir2 and FoxO Activation

桦木酸通过激活Sir2和FoxO延长果蝇的寿命

Hye-Yeon Lee,Kyung-Jin Min

A phase I randomized study to evaluate safety, pharmacokinetics, and pharmacodynamics of SIR2446M, a selective RIPK1 inhibitor, in healthy participants

一项 I 期随机研究,旨在评估选择性 RIPK1 抑制剂 SIR2446M 在健康受试者中的安全性、药代动力学和药效学。

Sun, Ana Liza Andresan; Gillies, John David; Shen, Yang; Deng, Huajun; Xue, Fenchao; Ma, Yongfen; Song, Linan

Strain background of Candida albicans interacts with SIR2 to alter phenotypic switching

白色念珠菌菌株背景与 SIR2 相互作用以改变表型转换

Andrew L Woodruff, Judith Berman, Matthew Anderson

Sirtuin 6 Overexpression Improves Rotator Cuff Tendon-to-Bone Healing in the Aged

Sirtuin 6 过度表达可改善老年人肩袖腱骨愈合

Young Jae Moon, Baoning Cui, Se-Young Cho, Jae Won Hwang, Hee-Chung Chung, Joseph Kwon, Duwoon Kim, Kyu Yun Jang, Jung Ryul Kim, Sung Il Wang

The role of SIRT2 inhibition on the aging process of brain in male rats

SIRT2抑制对雄性大鼠脑衰老过程的影响

K G Akbulut, A Keskin-Aktan, S A Abgarmi, H Akbulut

Sirt6 Activation Ameliorates Inflammatory Bone Loss in Ligature-Induced Periodontitis in Mice

Sirt6激活可改善小鼠结扎诱导牙周炎中的炎症性骨丢失

Myung Jin Lee ,Hyang Hwa Ryu ,Jae Won Hwang ,Jung Ryul Kim ,Eui-Sic Cho ,Jin Kyeong Choi ,Young Jae Moon

A novel allele of SIR2 reveals a heritable intermediate state of gene silencing

SIR2 的一个新等位基因揭示了基因沉默的可遗传中间状态

Delaney Farris ,Daniel S Saxton ,Jasper Rine