日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SP140-RESIST pathway regulates interferon mRNA stability and antiviral immunity

SP140-RESIST通路调控干扰素mRNA稳定性及抗病毒免疫

Kristen C Witt,Adam Dziulko,Joohyun An,Filip Pekovic,Arthur Xiuyuan Cheng,Grace Y Liu,Ophelia Vosshall Lee,David J Turner,Azra Lari,Moritz M Gaidt,Roberto Chavez,Stefan A Fattinger,Preethy Abraham,Harmandeep Dhaliwal,Angus Y Lee,Dmitri I Kotov,Laurent Coscoy,Britt A Glaunsinger,Eugene Valkov,Edward B Chuong,Russell E Vance

Anti-Mi2 autoantibodies target PHD fingers of SP140L and TIF1γ, while anti-TIF1γ autoantibodies primarily bind TIF1γ outside the PHD region

抗Mi2自身抗体靶向SP140L和TIF1γ的PHD结构域,而抗TIF1γ自身抗体主要结合TIF1γ的PHD结构域之外的区域。

Pinal-Fernandez, Iago; Musai, Jon; Casal-Dominguez, Maria; Pak, Katherine; Kaplan, Mariana; Warner, Blake M; Rider, Lisa G; Aggarwal, Rohit; Oddis, Chester V; Moghadam-Kia, Siamak; Garrabou, Gloria; Selva-O'Callaghan, Albert; Milisenda, Jose C; Chiorini, John A; Mammen, Andrew L; Burbelo, Peter D

SP140 limits type I interferon-driven pathology, preserving T cell motility and promoting resistance in tuberculosis

SP140 可限制 I 型干扰素驱动的病理,从而保持 T 细胞的运动能力并促进结核病的抵抗力。

Caouaille, Maxime; Fromont, Léa; Shinkawa, Tomoyo; Faucher, Marion; Abdul Hamid, Aizat Iman; Mazères, Serge; Duvergé, Yaël; Lorreyte, Yohan; Näser, Emmanuelle; Behar, Samuel M; Lefrançais, Emma; Neyrolles, Olivier; Hudrisier, Denis

Anti-Mi2 autoantibodies target the PHD fingers of SP140L and TIF1γ, while anti-TIF1γ autoantibodies primarily recognize epitopes outside the PHD region of TIF1γ

抗Mi2自身抗体靶向SP140L和TIF1γ的PHD结构域,而抗TIF1γ自身抗体主要识别TIF1γ的PHD结构域以外的表位。

Pinal-Fernandez, Iago; Musai, Jon; Casal-Dominguez, Maria; Pak, Katherine; Kaplan, Mariana; Warner, Blake M; Rider, Lisa G; Aggarwal, Rohit; Oddis, Chester V; Moghadam-Kia, Siamak; Garrabou, Gloria; Selva-O'Callaghan, Albert; Milisenda, Jose C; Chiorini, John A; Mammen, Andrew L; Burbelo, Peter D

Transcriptional regulators SP110 and SP140 modulate inflammatory response genes in Mycobacterium tuberculosis-infected human macrophages

转录调控因子SP110和SP140调节结核分枝杆菌感染的人类巨噬细胞中的炎症反应基因

Hajime Nakamura,Haruka Hikichi,Shintaro Seto,Minako Hijikata,Naoto Keicho

Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease

免疫染色质阅读器SP140调节肠道菌群和炎症性肠病风险

Isabella Fraschilla ,Hajera Amatullah ,Raza-Ur Rahman ,Kate L Jeffrey

Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140

通过选择性抑制表观遗传阅读蛋白SP140来调节巨噬细胞的炎症功能

Mohammed Ghiboub ,Jan Koster ,Peter D Craggs ,Andrew Y F Li Yim ,Anthony Shillings ,Sue Hutchinson ,Ryan P Bingham ,Kelly Gatfield ,Ishtu L Hageman ,Gang Yao ,Heather P O'Keefe ,Aaron Coffin ,Amish Patel ,Lisa A Sloan ,Darren J Mitchell ,Thomas G Hayhow ,Laurent Lunven ,Robert J Watson ,Christopher E Blunt ,Lee A Harrison ,Gordon Bruton ,Umesh Kumar ,Natalie Hamer ,John R Spaull ,Danny A Zwijnenburg ,Olaf Welting ,Theodorus B M Hakvoort ,Anje A Te Velde ,Johan van Limbergen ,Peter Henneman ,Rab K Prinjha ,Menno P J de Winther ,Nicola R Harker # ,David F Tough # ,Wouter J de Jonge #

The Role of Myrrh Metabolites in Cancer, Inflammation, and Wound Healing: Prospects for a Multi-Targeted Drug Therapy

没药代谢物在癌症、炎症和伤口愈合中的作用:多靶点药物治疗的前景

Rasha Saad Suliman, Sahar Saleh Alghamdi, Rizwan Ali, Dimah Aljatli, Norah Abdulaziz Aljammaz, Sarah Huwaizi, Rania Suliman, Khawla Mohammed Kahtani, Ghadeer M Albadrani, Tlili Barhoumi, Abdulelah Altolayyan, Ishrat Rahman

Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons

转录调节因子SP140通过抑制I型干扰素在抵抗细菌感染中的作用

Daisy X Ji # ,Kristen C Witt # ,Dmitri I Kotov ,Shally R Margolis ,Alexander Louie ,Victoria Chevée ,Katherine J Chen ,Moritz M Gaidt ,Harmandeep S Dhaliwal ,Angus Y Lee ,Stephen L Nishimura ,Dario S Zamboni ,Igor Kramnik ,Daniel A Portnoy ,K Heran Darwin ,Russell E Vance

Plant Nitrate Reductases Regulate Nitric Oxide Production and Nitrogen-Fixing Metabolism During the Medicago truncatula-Sinorhizobium meliloti Symbiosis

植物硝酸盐还原酶调节苜蓿-苜蓿中华根瘤菌共生过程中的一氧化氮产生和固氮代谢

Antoine Berger, Alexandre Boscari, Natasha Horta Araújo, Mickaël Maucourt, Mohamed Hanchi, Stéphane Bernillon, Dominique Rolin, Alain Puppo, Renaud Brouquisse