日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epigenetic Dysregulation of the NKX2-1/SPDEF Axis Drives Persistent Goblet Cell Differentiation and Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease

NKX2-1/SPDEF轴的表观遗传失调驱动慢性阻塞性肺疾病中持续的杯状细胞分化和上皮屏障功能障碍

Shiota, Ayaka; Kan-O, Keiko; Ishii, Yumiko; Koga, Tomoaki; Sawada, Takeshi; Yasunaga, Kei-Ichiro; Usuki, Shingo; Katsuno, Tatsuya; Inoue, Shigesato; Ogawa, Tomohiro; Jo, Akihiro; Fukuyama, Satoru; Nakao, Mitsuyoshi; Ogata, Hiroaki; Kido, Mizuho A; Tsukita, Sachiko; Matsumoto, Koichiro; Okamoto, Isamu

The RNA-binding protein Imp1 promotes a Spdef transcriptional program and mucus fucosylation during necrotizing enterocolitis.

RNA 结合蛋白 Imp1 在坏死性小肠结肠炎期间促进 Spdef 转录程序和粘液岩藻糖基化。

Assessing the Tumor Suppressive Impact and Regulatory Mechanisms of SPDEF Expression in Breast Cancer

评估SPDEF表达在乳腺癌中的肿瘤抑制作用和调控机制

Solanky, Maansi; Khosla, Maninder; Alahari, Suresh K

CpG dinucleotide methylation of the SPDEF gene as a blood-based epigenetic biomarker for prostate cancer diagnosis

SPDEF基因的CpG二核苷酸甲基化作为前列腺癌诊断的血液表观遗传生物标志物

Ahmadianpour, Mohammad Vahid; Aleyasin, Seyed Ahmad

SPDEF ameliorates UUO-induced renal fibrosis by transcriptional activation of NR4A1

SPDEF 通过转录激活 NR4A1 改善 UUO 诱导的肾纤维化

Hongshuang Wang #, Ziheng Wei #, Chang Xu, Fang Fang, Zheng Wang, Yan Zhong, Xiangting Wang1

SPDEF drives pancreatic adenocarcinoma progression via transcriptional upregulation of S100A16 and activation of the PI3K/AKT signaling pathway

SPDEF通过转录上调S100A16和激活PI3K/AKT信号通路促进胰腺腺癌进展

Jiang, Hang; Xue, Zhiqian; Zhao, Liping; Wang, Boyuan; Wang, Chenfei; Song, Haihan; Sun, Jianjun

SPDEF enhances cancer stem cell-like properties and tumorigenesis through directly promoting GALNT7 transcription in luminal breast cancer

SPDEF通过直接促进管腔型乳腺癌中GALNT7的转录,增强癌症干细胞样特性和肿瘤发生。

Jingyuan Li #,Xue Wan #,Dan Xie #,Hui Yuan,Qin Pei,Yanan Luo,Yiyu Chen,Jiawen Xian,Ting Ye

Development and characterization of an ETV1 rabbit monoclonal antibody for the immunohistochemical detection of ETV1 expression in cancer tissue specimens

ETV1 兔单克隆抗体的开发和表征,用于免疫组织化学检测癌症组织标本中的 ETV1 表达

Cara Schafer, Denise Young, Harpreet Singh, Rahul Jayakrishnan, Sreedatta Banerjee, Yingjie Song, Albert Dobi, Gyorgy Petrovics, Sudhir Srivastava, Shiv Srivastava, Isabell A Sesterhenn, Gregory T Chesnut, Shyh-Han Tan

The subtype-specific molecular function of SPDEF in breast cancer and insights into prognostic significance

SPDEF在乳腺癌亚型特异性分子功能及其预后意义

Ye, Ting; Li, Jingyuan; Feng, Jia; Guo, Jinglan; Wan, Xue; Xie, Dan; Liu, Jinbo

Efficient RNP-directed Human Gene Targeting Reveals SPDEF Is Required for IL-13-induced Mucostasis

高效的RNP导向人类基因靶向揭示SPDEF是IL-13诱导的黏液潴留所必需的

Koh, Kyung Duk; Siddiqui, Sana; Cheng, Dan; Bonser, Luke R; Sun, Dingyuan I; Zlock, Lorna T; Finkbeiner, Walter E; Woodruff, Prescott G; Erle, David J