日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Epigenetic and O-glycosylation regulation of p66Shc mitigates mitochondrial oxidative stress in aortic dissection

p66Shc的表观遗传和O-糖基化调控可减轻主动脉夹层中的线粒体氧化应激

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.124508
Zhang, Wenjun; Liu, Wanjun; Zhong, Xiaodan; Dai, Lei; Liu, Xiaolei; Li, Shiliang; Jiang, Hongcheng; He, Xingwei; Dong, Wei; Lu, Lijuan; Zhu, Li; Madhusudhan, Thati; Wang, Hongjie; Zeng, Hesong
表观遗传
氧化应激
信号转导
Shc
线粒体
毒理研究
发表日期：2026
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Retraction: Short communication: Upregulation of hypoxia/reoxygenation-induced Shc3 by downregulated miR-455-5p, suppresses trophoblast invasion and is associated with placental inflammation and angiogenesis in preeclampsia

撤稿声明：简讯：miR-455-5p下调诱导缺氧/复氧上调Shc3，抑制滋养层细胞侵袭，并与先兆子痫的胎盘炎症和血管生成相关

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0344272
炎症
炎症/感染
Shc
细胞生物学
血管生成
发表日期：2026
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Correction: Phosphorylation of p66Shc and forkhead proteins mediates Aβ toxicity

更正：p66Shc 和叉头蛋白的磷酸化介导 Aβ 毒性

期刊:Journal of Cell Biology
影响因子:6.4
doi:10.1083/jcb.20041004106232025c
Smith, Wanli W; Norton, Darrell D; Gorospe, Myriam; Jiang, Haibing; Nemoto, Shino; Holbrook, Nikki J; Finkel, Toren; Kusiak, John W
信号转导
磷酸化
毒理研究
Shc
发表日期：2025
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Protective Role of p66Shc Deletion in Physiological Renal Aging: Effects on G Protein-Coupled Receptor 124 Expression and Associated Cellular Senescence.

p66Shc 缺失在生理性肾脏衰老中的保护作用：对 G 蛋白偶联受体 124 表达和相关细胞衰老的影响。

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms262211096
细胞生物学
发育与干细胞
Shc
Senescence
细胞衰老
发表日期：2025
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The Role of p66Shc in Cancer: Molecular Mechanisms and Therapeutic Implications

p66Shc在癌症中的作用：分子机制和治疗意义

期刊:Journal of Cellular and Molecular Medicine
影响因子:4.2
doi:10.1111/jcmm.70737
Zaeifi, Davood; Jamialahmadi, Khadijeh; Karimi, Gholamreza
肿瘤
Shc
肿瘤免疫
发表日期：2025
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Targeting p66Shc to restore K(ATP) channel and renal microvascular responses in a preclinical model of diabetic nephropathy

在糖尿病肾病临床前模型中，靶向 p66Shc 可恢复 K(ATP) 通道和肾脏微血管反应。

期刊:Frontiers in Physiology
影响因子:3.4
doi:10.3389/fphys.2025.1620591
Miller, Bradley; Imig, John; Goorani, Samaneh; Schupbach, Perrin; Hays, Franklin; Benbrook, Doris M; Sorokin, Andrey
糖尿病
Shc
糖尿病肾病
代谢
发表日期：2025
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RETRACTED: Short communication: Upregulation of hypoxia/reoxygenation-induced Shc3 by downregulated miR-455-5p, suppresses trophoblast invasion and is associated with placental inflammation and angiogenesis in preeclampsia

撤稿：简讯：miR-455-5p下调诱导缺氧/复氧上调Shc3，抑制滋养层细胞侵袭，并与先兆子痫的胎盘炎症和血管生成相关

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0314544
Gong, Hui-Zhi; Guan, Jing; Pan, Ying-Zi; Ding, Hong-Juan; Shi, Ai-Wu; Gu, Ning
炎症
炎症/感染
Shc
细胞生物学
血管生成
发表日期：2025
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Non-Ser36 phosphorylated p66Shc inhibits TRPC-dependent and TRPC-independent calcium influx in vascular smooth muscle cells

非Ser36磷酸化的p66Shc抑制血管平滑肌细胞中TRPC依赖性和TRPC非依赖性钙离子内流。

期刊:Biochemical and Biophysical Research Communications
影响因子:2.2
doi:10.1016/j.bbrc.2025.152776
Schupbach, Perrin; Miller, Bradley; Sorokin, Andrey
信号转导
细胞生物学
磷酸化
Shc
发表日期：2025
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p66Shc Mediates SUMO2-induced Endothelial Dysfunction

p66Shc介导SUMO2诱导的内皮功能障碍

期刊:
影响因子:
doi:10.1101/2024.01.24.577109
Kumar, Jitendra; Uppulapu, Shravan K; Kumari, Sujata; Sharma, Kanika; Paradee, William; Yadav, Ravi Prakash; Kumar, Vikas; Kumar, Santosh
SUMO2
SUMO
Shc
发表日期：2025
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Corrigendum to "LRP1 activation attenuates white matter injury by modulating microglial polarization through Shc1/PI3K/Akt pathway after subarachnoid hemorrhage in rats" [Redox Biol. 21 (2019) 101121]

对“LRP1激活通过Shc1/PI3K/Akt通路调节小胶质细胞极化来减轻大鼠蛛网膜下腔出血后白质损伤”的更正[Redox Biol. 21 (2019) 101121]

期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2024.103098
Peng, Jianhua; Pang, Jinwei; Huang, Lei; Enkhjargal, Budbazar; Zhang, Tongyu; Mo, Jun; Wu, Pei; Xu, Weilin; Zuo, Yuchun; Peng, Jun; Zuo, Gang; Chen, Ligang; Tang, Jiping; Zhang, John H; Jiang, Yong
胶质细胞
信号转导
PI3K/Akt
Shc
Rat
LRP1
细胞生物学
发表日期：2024
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