PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial
针对 PSMA 的 TGFβ 不敏感装甲 CAR-T 细胞在转移性去势抵抗性前列腺癌中的应用:一项 1 期临床试验
期刊:Nature Medicine
影响因子:58.7
doi:10.1038/s41591-022-01726-1
Vivek Narayan, Julie S Barber-Rotenberg, In-Young Jung #, Simon F Lacey #, Andrew J Rech #, Megan M Davis #, Wei-Ting Hwang, Priti Lal, Erica L Carpenter, Shannon L Maude, Gabriela Plesa, Neha Vapiwala, Anne Chew, Michael Moniak, Ronnie A Sebro, Michael D Farwell, Amy Marshall, Joan Gilmore, Lester
信号转导
免疫
细胞生物学
肿瘤
前列腺癌
T细胞
肿瘤细胞
FlowCytometry
TGF-β
Smad2/Smad3