日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial

针对 PSMA 的 TGFβ 不敏感装甲 CAR-T 细胞在转移性去势抵抗性前列腺癌中的应用:一项 1 期临床试验

Vivek Narayan, Julie S Barber-Rotenberg, In-Young Jung #, Simon F Lacey #, Andrew J Rech #, Megan M Davis #, Wei-Ting Hwang, Priti Lal, Erica L Carpenter, Shannon L Maude, Gabriela Plesa, Neha Vapiwala, Anne Chew, Michael Moniak, Ronnie A Sebro, Michael D Farwell, Amy Marshall, Joan Gilmore, Lester

Heligmosomoides polygyrus bakeri Infection Decreases Smad7 Expression in Intestinal CD4+ T Cells, Which Allows TGF-β to Induce IL-10-Producing Regulatory T Cells That Block Colitis

Heligmosomoides polygyrus bakeri 感染可降低肠道 CD4+ T 细胞中的 Smad7 表达,从而使 TGF-β 诱导产生 IL-10 的调节性 T 细胞,从而阻断结肠炎

Long Hang, Sangeeta Kumar, Arthur M Blum, Joseph F Urban Jr, Massimo C Fantini, Joel V Weinstock

Dominant-Negative TGF-β Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication

显性负性 TGF-β 受体增强 PSMA 靶向人类 CAR T 细胞增殖并增强前列腺癌根除

Christopher C Kloss, Jihyun Lee, Aaron Zhang, Fang Chen, Jan Joseph Melenhorst, Simon F Lacey, Marcela V Maus, Joseph A Fraietta, Yangbing Zhao, Carl H June

TGF-β1 induces EMT reprogramming of porcine bladder urothelial cells into collagen producing fibroblasts-like cells in a Smad2/Smad3-dependent manner.

TGF-β1 以 Smad2/Smad3 依赖的方式诱导猪膀胱尿路上皮细胞发生 EMT 重编程,生成胶原蛋白生成成纤维细胞样细胞。