日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Substrate specificity and protein stability drive the divergence of plant-specific DNA methyltransferases

底物特异性和蛋白质稳定性驱动植物特异性 DNA 甲基转移酶的分化

Jianjun Jiang, Jia Gwee, Jian Fang, Sarah M Leichter, Dean Sanders, Xinrui Ji, Jikui Song, Xuehua Zhong

Pooled endogenous protein tagging and recruitment for systematic profiling of protein function

汇集内源性蛋白质标记和募集,用于系统分析蛋白质功能

Yevgeniy V Serebrenik, Deepak Mani, Timothé Maujean, George M Burslem, Ophir Shalem

Orm proteins control ceramide synthesis and endocytosis via LCB-mediated Ypk1 regulation

Orm 蛋白通过 LCB 介导的 Ypk1 调节控制神经酰胺的合成和内吞作用

Jihui Ren, Robert Rieger, Nivea Pereira de Sa, Douglas Kelapire, Maurizio Del Poeta, Yusuf A Hannun

The gag-like gene RTL8 antagonizes PEG10-mediated virus like particles

gag 样基因 RTL8 可拮抗 PEG10 介导的病毒样颗粒

Will Campodonico, Harihar M Mohan, Phuoc T Huynh, Holly H Black, Cristina I Lau, Henry L Paulson, Lisa M Sharkey, Alexandra M Whiteley

Systemic inhibition of de novo purine biosynthesis prevents weight gain and improves metabolic health by increasing thermogenesis and decreasing food intake

系统性抑制嘌呤从头生物合成可防止体重增加,并通过增加产热作用和减少食物摄入来改善代谢健康

Jacob W Myers, Woo Yong Park, Alexander M Eddie, Abhijit B Shinde, Praveena Prasad, Alexandria C Murphy, Michael Z Leonard, Julia A Pinette, Jessica J Rampy, Claudia Montufar, Zayedali Shaikh, Tara T Hickman, Garrett N Reynolds, Nathan C Winn, Louise Lantier, Sun H Peck, Katie C Coate, Roland W Stei

Loss or inhibition of lysosomal acid lipase in vitro leads to cholesteryl ester accumulation without affecting muscle formation or mitochondrial function

体外溶酶体酸性脂肪酶的丧失或抑制会导致胆固醇酯的积累,而不会影响肌肉形成或线粒体功能

Alena Akhmetshina, Laszlo Schooltink, Melina Amor, Katharina B Kuentzel, Silvia Rainer, Ananya Nandy, Hansjoerg Habisch, Tobias Madl, Elizabeth Rendina-Ruedy, Katharina Leithner, Nemanja Vujić, Dagmar Kratky

Homeostatic control of an iron repressor in a GI tract resident

胃肠道居民体内铁阻遏物的稳态控制

Yuanyuan Wang #, Yinhe Mao #, Xiaoqing Chen, Xinhuang Huang, Zhongyi Jiang, Kaiyan Yang, Lixing Tian, Tong Jiang, Yun Zou, Xiaoyuan Ma, Chaoyue Xu, Zili Zhou, Xianwei Wu, Lei Pan, Huaping Liang, Lin Zhong, Changbin Chen

Quantitative analysis of taxane drug target engagement of microtubules in circulating tumor cells from metastatic castration resistant prostate cancer patients treated with CRXL301, a nanoparticle of docetaxel

对接受 CRXL301(一种多西他赛纳米颗粒)治疗的转移性去势抵抗性前列腺癌患者循环肿瘤细胞中紫杉烷类药物靶点与微管的结合情况进行定量分析

Eiman Mukhtar ,Daniel Worroll ,Giuseppe Galletti ,Shelly Schuster ,Sarina A Piha-Paul ,Paraskevi Giannakakou

Establishment and characterization of transformed goat primary cells by expression of simian virus 40 large T antigen for orf virus propagations

表达猴病毒 40 大 T 抗原的转化山羊原代细胞的建立和鉴定,用于羊口疮病毒的增殖

Yumiko Yamada, Guan-Ru Liao, Ching-Yu Tseng, Yeu-Yang Tseng, Wei-Li Hsu

Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic X. laevis Models of Retinitis Pigmentosa

组蛋白去乙酰化酶抑制剂活性介导的丙戊酸治疗在四种转基因 X. laevis 视网膜色素变性模型中的相反作用

Ruanne Y J Vent-Schmidt, Runxia H Wen, Zusheng Zong, Colette N Chiu, Beatrice M Tam, Christopher G May, Orson L Moritz