日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

BMX inhibition overcomes small cell lung cancer chemoresistance by stabilizing E2F1 via ERK1/2-Cyclin D1/CDK4/6 axis.

BMX抑制剂通过ERK1/2-Cyclin D1/CDK4/6轴稳定E2F1，从而克服小细胞肺癌的化疗耐药性。

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-026-02644-1
Wu Ting, Qi Shuang, Shi Chenliang, Wu Chao, Liu Qingwang, Hu Chen, Hu Jie, Wang Aoli, Liu Jing, Qi Ziping, Wang Wenchao, Liu Qingsong
肺癌
细胞生物学
BMX
CYC
CDK4
E2F1
erk1
Cyclin D1
MAPK/ERK
发表日期：2026
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BMX-001, a clinically relevant radioprotector, can reverse radiation-induced fibrosis when given three weeks after radiation, in part, by restoring methylation.

BMX-001 是一种具有临床意义的放射防护剂，在放射治疗后三周给予，可以逆转放射引起的纤维化，部分原因是它能恢复甲基化。

期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2026.104020
Myers Molly S, Kosmacek Elizabeth A, Liew Chia Sin, Lushnikov Alexander J, Chatterjee Arpita, Marky Luis A, Riethoven Jean-Jack M, Oberley-Deegan Rebecca E
表观遗传
BMX
发表日期：2026
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CDH4/UBA1/RBMX axis promotes polycystic ovary syndrome progression through YAP1 activation

CDH4/UBA1/RBMX轴通过YAP1激活促进多囊卵巢综合征的进展。

期刊:Cellular & Molecular Biology Letters
影响因子:10.2
doi:10.1186/s11658-026-00900-4
Xu, Ning; Yu, Bo; Li, Yingying; Yang, Yuxi; Wang, Yalong; Fang, Lingling; Wu, Hongliang; Luan, Yingyi; Yin, Chenghong
YAP1
多囊卵巢综合征
BMX
YAP
UBA1
免疫/内分泌
发表日期：2026
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Correction: Pan et al. Therapeutic Potential of BMX-001 for Preventing Chemotherapy-Induced Peripheral Neuropathic Pain. Pharmaceuticals 2025, 18, 1159

更正：Pan 等人，《BMX-001 在预防化疗引起的周围神经性疼痛方面的治疗潜力》，Pharmaceuticals 2025, 18, 1159

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph19030351
Pan, Tianshu; Alimi, Olawale A; Liu, Bo; Krishnan, Mena A; Kuss, Mitchell; Shi, Wei; Krishnamurthy, Jairam; Dong, Jianghu James; Oberley-Deegan, Rebecca E; Duan, Bin
BMX
发表日期：2026
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DeSUMOylation of RBMX regulates exosomal sorting of cargo to promote renal tubulointerstitial fibrosis in diabetic kidney disease

RBMX去SUMO化调控外泌体货物分选，从而促进糖尿病肾病中的肾小管间质纤维化。

期刊:Journal of Advanced Research
影响因子:13
doi:10.1016/j.jare.2024.09.021
Yang, Yanlin; Ren, Shijing; Xue, Junyu; Dong, Wenhui; He, Wei; Luo, Jiayi; Li, Xiaomin; Xu, Haibin; Zheng, Zongji; Wang, Xiangyu; Wang, Ling; Guan, Meiping; Jia, Yijie; Xue, Yaoming
外泌体
SUMO
信号转导
BMX
代谢
糖尿病
糖尿病肾病
发表日期：2025
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Inhibition of tyrosine kinase BMX increases cell death in response to existing chemotherapeutic agents overcoming apoptotic resistance in cancer

酪氨酸激酶BMX的抑制可增强现有化疗药物诱导的细胞死亡，从而克服癌细胞的凋亡抵抗。

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-08131-9
Morad, Dalal; Skinner, Sam; Bowman, Karen; Seewooruthun, Chitra; Fox, Joanna L
肿瘤
凋亡
表观遗传
肿瘤免疫
信号转导
BMX
细胞生物学
发表日期：2025
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Cancer-Derived Exosomal LINC01615 Induces M2 Polarization of Tumor-Associated Macrophages via RBMX-EZH2 Axis to Promote Colorectal Cancer Progression

癌症来源的外泌体LINC01615通过RBMX-EZH2轴诱导肿瘤相关巨噬细胞M2极化，从而促进结直肠癌进展

期刊:International Journal of Nanomedicine
影响因子:6.5
doi:10.2147/IJN.S499381
Li, Anshu; Hong, Jiaxin; Ma, Xianxiong; Huang, Yongzhou; Jiang, Qi; Zhang, Chenggang; Wang, Yu; Huang, Yongming
巨噬细胞
外泌体
肿瘤
肠癌
肿瘤免疫
巨噬细胞
BMX
EZH2
细胞生物学
免疫/内分泌
发表日期：2025
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RBMX2 links Mycobacterium bovis infection to epithelial-mesenchymal transition and lung cancer progression

RBMX2 将牛分枝杆菌感染与上皮-间质转化和肺癌进展联系起来

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.107132
Wang, Chao; Peng, Yongchong; Yang, Hongxin; Jiang, Yanzhu; Khalid, Abdul Karim; Zhang, Kailun; Xie, Shengsong; Bermudez, Luiz; Yang, Yong; Zhang, Lei; Chen, Huanchun; Guo, Aizhen; Chen, Yingyu
肺癌
肿瘤
MX2
肿瘤免疫
炎症/感染
BMX
发表日期：2025
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Therapeutic Potential of BMX-001 for Preventing Chemotherapy-Induced Peripheral Neuropathic Pain

BMX-001在预防化疗引起的周围神经病理性疼痛方面的治疗潜力

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph18081159
Pan, Tianshu; Alimi, Olawale A; Liu, Bo; Krishnan, Mena A; Kuss, Mitchell; Shi, Wei; Krishnamurthy, Jairam; Dong, Jianghu James; Oberley-Deegan, Rebecca E; Duan, Bin
BMX
发表日期：2025
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Machine learning-based transcriptmics analysis reveals BMX, GRB10, and GADD45A as crucial biomarkers and therapeutic targets in sepsis

基于机器学习的转录组学分析揭示BMX、GRB10和GADD45A是脓毒症的关键生物标志物和治疗靶点

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1576467
Cheng, Yanwei; Peng, Haoran; Chen, Qiao; Xu, Lijun; Qin, Lijie
炎症/感染
败血症
BMX
发表日期：2025
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