日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

PTBP1 inhibition reprograms myogenesis to rescue impaired muscle regeneration in mdx mice through correcting E2A splicing

PTBP1抑制通过纠正E2A剪接重编程肌生成，从而挽救mdx小鼠受损的肌肉再生能力。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-70669-9
Fan, Shusheng; Liu, Xiaoyun; Pan, Qian; Tong, Haowei; Gui, Qiaoqiao; Guo, Guangyao; Hong, Huitao; Hu, Wanting; Huang, Xiaofei; Zhao, Lei; Li, Xihua; Yu, Qinwei; Zhang, Luyong; Jiang, Zhenzhou
TBP
E2A
PTBP1
发表日期：2026
文献求助 收藏

Cooperative clamp-mediated promoter recognition by poxviral RNA polymerase and its TBP/TFIIB-like partner.

痘病毒 RNA 聚合酶及其 TBP/TFIIB 样伴侣通过协同钳介导的启动子识别。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69571-1
Jungwirth Stefan, Bartuli Julia, Lamer Stephanie, Schlosser Andreas, Grimm Clemens, Fischer Utz
TBP
发表日期：2026
文献求助 收藏

The splicing factor PTBP1 interacts with RUNX1 and is required for leukemia cell survival

剪接因子PTBP1与RUNX1相互作用，是白血病细胞存活所必需的。

期刊:Leukemia
影响因子:13.4
doi:10.1038/s41375-025-02799-w
Dhir, Arjun; Ethell, Alexander; Watkins, Riley; Lam, Calvin; Tur-Rodriguez, Kevin; Persinger, Jimmie; Dobish, Kasidy K; Panda, Sipra; Buckley, Shannon M; Swenson, Samantha A; Brahma, Sandipan; Rowley, M Jordan; Hyde, R Katherine
RUNX1
白血病
PTBP1
TBP
细胞生物学
发表日期：2026
文献求助 收藏

PTBP1-mediated inhibition of circular RNA SCMH1 biogenesis impairs brain recovery after ischemic stroke.

PTBP1介导的环状RNA SCMH1生物合成抑制会损害缺血性中风后的脑恢复。

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.114179
Bai Ying, Han Bing, Zhang Yi, Wen Liying, Liu Chang, Wang Yu, Cui Jiafang, Zheng Bingjing, Cai Ningbo, Xu Lian, Shen Ling, Zhang Yuan, Yao Honghong
中风
心血管
神经科学
PTBP1
TBP
发表日期：2026
文献求助 收藏

The therapeutic potential and mechanisms of targeting the PTBP1/Nogo-A/NgR axis in PTSD induced by single prolonged stress in mice.

针对PTBP1/Nogo-A/NgR轴治疗小鼠单次长期应激诱发的PTSD的治疗潜力和机制。

期刊:Experimental and Molecular Medicine
影响因子:12.9
doi:10.1038/s12276-025-01629-4
PTBP1
TBP
Nogo-A
发表日期：2026
文献求助 收藏

PTPN1 Regulation via YBX1-PTBP1 Interaction Promotes Fibroblast Activation and Fibrotic Remodeling in the Lung.

PTPN1 通过 YBX1-PTBP1 相互作用进行调控，促进肺成纤维细胞活化和纤维化重塑。

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.123875
Liu Huibing, Xia Cong, Zhang Yingying, Gan Yulong, Cheng Lianhui, Wang Xuqian, Chang Airu, Zhao Wenyu, Li Bin, Wang Yaxuan, Li Yajun, Rosas Ivan, Yang Juntang, Yu Guoying, Wang Lan
细胞生物学
成纤维细胞
TBP
PTBP1
发表日期：2026
文献求助 收藏

The PTBP1-EZH2-DOCK2 axis promotes M1 microglial polarization and exacerbates neuronal apoptosis following spinal cord injury.

PTBP1-EZH2-DOCK2 轴促进 M1 小胶质细胞极化，加剧脊髓损伤后的神经元凋亡。

期刊:Journal of Orthopaedic Translation
影响因子:7.8
doi:10.1016/j.jot.2025.10.008
脊髓损伤
细胞生物学
神经科学
表观遗传
胶质细胞
PTBP1
TBP
EZH2
DOCK2
Apoptosis
凋亡
发表日期：2026
文献求助 收藏

NAD(H)-dependent corepressor CTBP1 integrates metabolic signals to drive oncogenic programs

NAD(H)依赖性辅阻遏物CTBP1整合代谢信号以驱动致癌程序

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2026.1797122
Akdaş, Enes Yağız; Schneider, Kirill; Lu, Dingyu; Hachani, Khouloud; Roberts, Erika Lynn; Ghanem, Mohamad; Bashiri Dezfouli, Ali; Wollenberg, Barbara
肿瘤
肿瘤免疫
信号转导
CTBP1
代谢
TBP
发表日期：2026
文献求助 收藏

PTBP1 supports mouse spermatogenesis by facilitating cytoskeletal organization through the mTORC2-PKCα pathway in Sertoli cells.

PTBP1 通过促进支持细胞中 mTORC2-PKCα 通路的细胞骨架组织来支持小鼠精子发生。

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-026-09636-5
Ozawa Manabu, Taguchi Jumpei, Mori Hideto, Kikuchi Mio, Muratani Masafumi, Yamamoto Takuya, Yamada Yasuhiro, Yoshida Nobuaki, Ikawa Masahito
mTOR
信号转导
PKCα
ORC2
PTBP1
TBP
细胞生物学
PKC
发表日期：2026
文献求助 收藏

[Retracted] LTBP2 promotes the migration and invasion of gastric cancer cells and predicts poor outcome of patients with gastric cancer

【已撤稿】LTBP2促进胃癌细胞的迁移和侵袭，并预示胃癌患者预后不良

期刊:International Journal of Oncology
影响因子:4.9
doi:10.3892/ijo.2026.5847
Wang, Jun; Liang, Wen-Jia; Min, Guang-Tao; Wang, Hong-Peng; Chen, Wei; Yao, Nan
胃癌
肿瘤
肿瘤免疫
TBP
细胞生物学
发表日期：2026
文献求助 收藏