TCR Vβ相关文献与解析，生知库 | 链接生命科学的每一步

Khoryati, Liliane; Sørensen, Signe Bech; Parizot, Christophe; Lautraite, Raphaëlle; Pineton de Chambrun, Marc; Gorochov, Guy; Mogensen, Trine H; Belot, Alexandre

T细胞

TCR Vβ

MIS

Combination of a novel TCR VÎ² chain-directed selective T cell activator with standard of care therapy for head and neck cancer improves antitumor responses and promotes regression of checkpoint-refractory tumor models.

将新型 TCR Vβ 链导向的选择性 T 细胞激活剂与头颈癌的标准治疗相结合，可改善抗肿瘤反应并促进检查点耐药肿瘤模型的消退。

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.6

doi:10.1136/jitc-2025-013158

Rosato Francesca, Santiago-Sanchez Ginette, Fabian Kellsye P, Padget Michelle R, Lee Jonelle K, Allen Clint Tanner, Su Zhen, Katragadda Madan, Moisan Jacques, Bayliffe Andrew, Schlom Jeffrey, Hodge James W

Predictive value of TCR Vβ-Jβ profile for adjuvant gefitinib in EGFR mutant NSCLC from ADJUVANT-CTONG 1104 trial

ADJUVANT-CTONG 1104试验中TCR Vβ-Jβ谱对EGFR突变型非小细胞肺癌辅助吉非替尼治疗的预测价值

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.152631

Chen, Cunte; Liu, Si-Yang Maggie; Chen, Yedan; Ou, Qiuxiang; Bao, Hua; Xu, Ling; Zhang, Yikai; Zhong, Wenzhao; Zhou, Qing; Yang, Xue-Ning; Shao, Yang; Wu, Yi-Long; Liu, Si-Yang; Li, Yangqiu

Polyclonal expansion of TCR Vbeta 21.3(+) CD4(+) and CD8(+) T cells is a hallmark of Multisystem Inflammatory Syndrome in Children

儿童多系统炎症综合征的标志是TCR Vβ21.3(+)CD4(+)和CD8(+)T细胞的多克隆扩增。

期刊:Science Immunology

影响因子:16.3

doi:10.1126/sciimmunol.abh1516

Moreews, Marion; Le Gouge, Kenz; Khaldi-Plassart, Samira; Pescarmona, Rémi; Mathieu, Anne-Laure; Malcus, Christophe; Djebali, Sophia; Bellomo, Alicia; Dauwalder, Olivier; Perret, Magali; Villard, Marine; Chopin, Emilie; Rouvet, Isabelle; Vandenesh, Francois; Dupieux, Céline; Pouyau, Robin; Teyssedre, Sonia; Guerder, Margaux; Louazon, Tiphaine; Moulin-Zinsch, Anne; Duperril, Marie; Patural, Hugues; Giovannini-Chami, Lisa; Portefaix, Aurélie; Kassai, Behrouz; Venet, Fabienne; Monneret, Guillaume; Lombard, Christine; Flodrops, Hugues; De Guillebon, Jean-Marie; Bajolle, Fanny; Launay, Valérie; Bastard, Paul; Zhang, Shen-Ying; Dubois, Valérie; Thaunat, Olivier; Richard, Jean-Christophe; Mezidi, Mehdi; Allatif, Omran; Saker, Kahina; Dreux, Marlène; Abel, Laurent; Casanova, Jean-Laurent; Marvel, Jacqueline; Trouillet-Assant, Sophie; Klatzmann, David; Walzer, Thierry; Mariotti-Ferrandiz, Encarnita; Javouhey, Etienne; Belot, Alexandre

Evidence for Non-Cancer-Specific T Cell Exhaustion in the Tcl1 Mouse Model for Chronic Lymphocytic Leukemia

Tcl1小鼠慢性淋巴细胞白血病模型中非癌症特异性T细胞耗竭的证据

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms22136648

Thomas Parigger ，Franz Josef Gassner ，Christian Scherhäufl ，Aryunni Abu Bakar ，Jan Philip Höpner ，Alexandra Hödlmoser ，Markus Steiner ，Kemal Catakovic ，Roland Geisberger ，Richard Greil ，Nadja Zaborsky

High-throughput sequencing reveals restricted TCR Vβ usage and public TCRβ clonotypes among pancreatic lymph node memory CD4(+) T cells and their involvement in autoimmune diabetes

高通量测序揭示了胰腺淋巴结记忆性CD4(+) T细胞中受限的TCR Vβ使用和公共TCRβ克隆型及其在自身免疫性糖尿病中的作用

期刊:Molecular Immunology

影响因子:3

doi:10.1016/j.molimm.2016.04.013

Marrero, Idania; Aguilera, Carlos; Hamm, David E; Quinn, Anthony; Kumar, Vipin

Flow cytometric analysis of the CD4+ TCR Vβ repertoire in the peripheral blood of children with type 1 diabetes mellitus, systemic lupus erythematosus and age-matched healthy controls

采用流式细胞术分析1型糖尿病、系统性红斑狼疮患儿及年龄匹配的健康对照组儿童外周血中CD4+ TCR Vβ谱系

期刊:BMC Immunology

影响因子:2.7

doi:10.1186/1471-2172-14-33

Tzifi, Flora; Kanariou, Maria; Tzanoudaki, Marianna; Mihas, Constantinos; Paschali, Evangelia; Chrousos, George; Kanaka-Gantenbein, Christina

In silico Analysis of TCR Vβ7 of Two Patients with Type 1 Diabetes Mellitus

对两名1型糖尿病患者的TCR Vβ7进行计算机模拟分析

期刊:Journal of Laboratory Physicians

影响因子:1

doi:10.4103/0974-2727.119845

Zhou, Jianwei; Kong, Cui; Wang, Xiukui; Jia, Yinfeng; Wang, Li; Chang, Hong; Sun, Lin

Relative quantification of TCR Vbeta-chain families by real time PCR for identification of clonal T-cell populations

利用实时PCR对TCR Vβ链家族进行相对定量，以鉴定克隆性T细胞群

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/1479-5876-6-34

Ochsenreither, Sebastian; Fusi, Alberto; Busse, Antonia; Nagorsen, Dirk; Schrama, David; Becker, Jürgen; Thiel, Eckhard; Keilholz, Ulrich

Identification of an altered peptide ligand based on the endogenously presented, rheumatoid arthritis-associated, human cartilage glycoprotein-39(263-275) epitope: an MHC anchor variant peptide for immune modulation

根据内源性呈递的类风湿性关节炎相关人类软骨糖蛋白-39（263-275）表位鉴定改变的肽配体：用于免疫调节的 MHC 锚变体肽

期刊:Arthritis Research & Therapy

影响因子:4.4

doi:10.1186/ar2269

Annemieke M H Boots, Henk Hubers, Milou Kouwijzer, Leontien den Hoed-van Zandbrink, Bernice M Westrek-Esselink, Cindy van Doorn, Rachel Stenger, Ebo S Bos, Marie-jose C van Lierop, Gijs F Verheijden, Cornelis M Timmers, Catharina J van Staveren

Shared TCR Vβ21.3+ T cell immunological signature between MIS-A and MIS-C

MIS-A 和 MIS-C 之间共享 TCR Vβ21.3+ T 细胞免疫学特征

Combination of a novel TCR VÎ² chain-directed selective T cell activator with standard of care therapy for head and neck cancer improves antitumor responses and promotes regression of checkpoint-refractory tumor models.

将新型 TCR Vβ 链导向的选择性 T 细胞激活剂与头颈癌的标准治疗相结合，可改善抗肿瘤反应并促进检查点耐药肿瘤模型的消退。

Predictive value of TCR Vβ-Jβ profile for adjuvant gefitinib in EGFR mutant NSCLC from ADJUVANT-CTONG 1104 trial

ADJUVANT-CTONG 1104试验中TCR Vβ-Jβ谱对EGFR突变型非小细胞肺癌辅助吉非替尼治疗的预测价值

Polyclonal expansion of TCR Vbeta 21.3(+) CD4(+) and CD8(+) T cells is a hallmark of Multisystem Inflammatory Syndrome in Children

儿童多系统炎症综合征的标志是TCR Vβ21.3(+)CD4(+)和CD8(+)T细胞的多克隆扩增。

Evidence for Non-Cancer-Specific T Cell Exhaustion in the Tcl1 Mouse Model for Chronic Lymphocytic Leukemia

Tcl1小鼠慢性淋巴细胞白血病模型中非癌症特异性T细胞耗竭的证据

High-throughput sequencing reveals restricted TCR Vβ usage and public TCRβ clonotypes among pancreatic lymph node memory CD4(+) T cells and their involvement in autoimmune diabetes

高通量测序揭示了胰腺淋巴结记忆性CD4(+) T细胞中受限的TCR Vβ使用和公共TCRβ克隆型及其在自身免疫性糖尿病中的作用

Flow cytometric analysis of the CD4+ TCR Vβ repertoire in the peripheral blood of children with type 1 diabetes mellitus, systemic lupus erythematosus and age-matched healthy controls

采用流式细胞术分析1型糖尿病、系统性红斑狼疮患儿及年龄匹配的健康对照组儿童外周血中CD4+ TCR Vβ谱系

In silico Analysis of TCR Vβ7 of Two Patients with Type 1 Diabetes Mellitus

对两名1型糖尿病患者的TCR Vβ7进行计算机模拟分析

Relative quantification of TCR Vbeta-chain families by real time PCR for identification of clonal T-cell populations

利用实时PCR对TCR Vβ链家族进行相对定量，以鉴定克隆性T细胞群

Identification of an altered peptide ligand based on the endogenously presented, rheumatoid arthritis-associated, human cartilage glycoprotein-39(263-275) epitope: an MHC anchor variant peptide for immune modulation

根据内源性呈递的类风湿性关节炎相关人类软骨糖蛋白-39（263-275）表位鉴定改变的肽配体：用于免疫调节的 MHC 锚变体肽