TFE2相关文献与解析，生知库 | 链接生命科学的每一步

Corneal fibrosis abrogation by a localized AAV-mediated inhibitor of differentiation 3 (Id3) gene therapy in rabbit eyes in vivo

局部 AAV 介导的分化抑制剂 3 (Id3) 基因治疗在兔眼体内消除角膜纤维化

doi:10.1016/j.ymthe.2022.06.018

Suneel Gupta, Michael K Fink, Duraisamy Kempuraj, Nishant R Sinha, Lynn M Martin, Landon M Keele, Prashant R Sinha, Elizabeth A Giuliano, Nathan P Hesemann, Sudhanshu P Raikwar, Shyam S Chaurasia, Rajiv R Mohan

The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude

转录抑制因子ID2通过控制TCF1的表达水平来促进自然杀伤细胞的成熟。

期刊:Journal of Experimental Medicine

影响因子:12.6

doi:10.1084/jem.20202032

Zhong-Yin Li ，Rosemary E Morman ，Emma Hegermiller ，Mengxi Sun ，Elizabeth T Bartom ，Mark Maienschein-Cline ，Mikael Sigvardsson ，Barbara L Kee

Decreased expression of ATF3, orchestrated by β-catenin/TCF3, miR-17-5p and HOXA11-AS, promoted gastric cancer progression via increased β-catenin and CEMIP

在 β-catenin/TCF3、miR-17-5p 和 HOXA11-AS 的调控下，ATF3 表达降低，通过增加 β-catenin 和 CEMIP 促进胃癌进展

期刊:Experimental and Molecular Medicine

影响因子:9.5

doi:10.1038/s12276-021-00694-9

Guohua Xie #, Ping Dong #, Hui Chen, Ling Xu, Yi Liu, Yanhui Ma, Yingxia Zheng, Junyao Yang, Yunlan Zhou, Lei Chen, Lisong Shen

E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma

E47上调ΔNp63α以促进鳞状细胞癌的生长

期刊:Cell Death & Disease

影响因子:8.1

doi:10.1038/s41419-021-03662-3

Jing Xu # ，Fengtian Li # ，Ya Gao ，Rongtian Guo ，Liangping Ding ，Mengyuan Fu ，Yong Yi ，Hu Chen ，Zhi-Xiong Jim Xiao ，Mengmeng Niu

Loss of ID3 drives papillary thyroid cancer metastasis by targeting E47-mediated epithelial to mesenchymal transition

ID3 缺失通过靶向 E47 介导的上皮-间质转化驱动乳头状甲状腺癌转移

期刊:Cell Death Discovery

影响因子:6.1

doi:10.1038/s41420-021-00614-w

Sunwang Xu #, Caiqin Mo #, Junyu Lin #, Yixing Yan, Xiaoyu Liu, Kunlin Wu, Huihao Zhang, Youzhi Zhu, Ling Chen, Xiangjin Chen

Thyroid Hormone Receptor α1 Mutants Impair B Lymphocyte Development in a Mouse Model

甲状腺激素受体 α1 突变体损害小鼠模型中的 B 淋巴细胞发育

期刊:Thyroid

影响因子:5.8

doi:10.1089/thy.2019.0782

Sunmi Park, Xuguang Zhu, Minjun Kim, Li Zhao, Sheue-Yann Cheng

AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase

AR 阴性前列腺癌容易因 JMJD1C 去甲基化酶的缺失而受损

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.2026324118

Yohei Yoshihama, Kyle A LaBella, Eiru Kim, Lori Bertolet, Medina Colic, Jiexi Li, Xiaoying Shang, Chang-Jiun Wu, Denise J Spring, Y Alan Wang, Traver Hart, Ronald A DePinho

Depletion of ID3 enhances mesenchymal stem cells therapy by targeting BMP4 in Sjögren's syndrome

消除 ID3 可通过靶向 BMP4 来增强干燥综合征中的间充质干细胞治疗

期刊:Cell Death & Disease

影响因子:8.1

doi:10.1038/s41419-020-2359-6

Lei Hu, Junji Xu, Tingting Wu, Zhipeng Fan, Lingyun Sun, Yi Liu, Yan Li, Chunmei Zhang, Jingsong Wang, Yaozhong Ding, Songlin Wang

The transcription factor E2A drives neural differentiation in pluripotent cells

转录因子E2A驱动多能干细胞的神经分化。

期刊:Development

影响因子:3.7

doi:10.1242/dev.184093

Chandrika Rao ，Mattias Malaguti ，John O Mason ，Sally Lowell

Single‑nucleotide polymorphism rs6592645 confers asthma risk through regulating LRRC32 expression

单核苷酸多态性 rs6592645 通过调节 LRRC32 表达导致哮喘风险

Corneal fibrosis abrogation by a localized AAV-mediated inhibitor of differentiation 3 (Id3) gene therapy in rabbit eyes in vivo

局部 AAV 介导的分化抑制剂 3 (Id3) 基因治疗在兔眼体内消除角膜纤维化

The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude

转录抑制因子ID2通过控制TCF1的表达水平来促进自然杀伤细胞的成熟。

Decreased expression of ATF3, orchestrated by β-catenin/TCF3, miR-17-5p and HOXA11-AS, promoted gastric cancer progression via increased β-catenin and CEMIP

在 β-catenin/TCF3、miR-17-5p 和 HOXA11-AS 的调控下，ATF3 表达降低，通过增加 β-catenin 和 CEMIP 促进胃癌进展

E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma

E47上调ΔNp63α以促进鳞状细胞癌的生长

Loss of ID3 drives papillary thyroid cancer metastasis by targeting E47-mediated epithelial to mesenchymal transition

ID3 缺失通过靶向 E47 介导的上皮-间质转化驱动乳头状甲状腺癌转移

Thyroid Hormone Receptor α1 Mutants Impair B Lymphocyte Development in a Mouse Model

甲状腺激素受体 α1 突变体损害小鼠模型中的 B 淋巴细胞发育

AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase

AR 阴性前列腺癌容易因 JMJD1C 去甲基化酶的缺失而受损

Depletion of ID3 enhances mesenchymal stem cells therapy by targeting BMP4 in Sjögren's syndrome

消除 ID3 可通过靶向 BMP4 来增强干燥综合征中的间充质干细胞治疗

The transcription factor E2A drives neural differentiation in pluripotent cells

转录因子E2A驱动多能干细胞的神经分化。