日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeted demethylation of the BRD7 promoter based on CRISPR/dCas9 system inhibits the malignant progression of nasopharyngeal carcinoma.

基于 CRISPR/dCas9 系统的 BRD7 启动子靶向去甲基化可抑制鼻咽癌的恶性进展。

Brd7 loss reawakens dormant metastasis initiating cells in lung by forging an immunosuppressive niche

Brd7 缺失通过构建免疫抑制微环境,重新激活肺部休眠的转移起始细胞。

Jayanta Mondal # ,Junfeng Zhang # ,Feng Qing ,Shunping Li ,Dhiraj Kumar ,Jason T Huse ,Filippo G Giancotti

Correction: Tumor- and host-derived heparanase-2 (Hpa2) attenuates tumorigenicity: role of Hpa2 in macrophage polarization and BRD7 nuclear localization

更正:肿瘤和宿主来源的肝素酶-2 (Hpa2) 减弱肿瘤发生能力:Hpa2 在巨噬细胞极化和 BRD7 核定位中的作用

Soboh, Soaad; Vorontsova, Avital; Farhoud, Malik; Barash, Uri; Naroditsky, Inna; Gross-Cohen, Miriam; Weissmann, Marina; Nishioka, Yasuhiko; Woolf, Adrian S; Roberts, Neil A; Shaked, Yuval; Ilan, Neta; Vlodavsky, Israel

TRIM25 degrades BRD7 protein stability through the ubiquitin proteasome pathway to promote breast cancer progression and paclitaxel resistance by activating YB1/Bcl-2 transcription axis.

TRIM25 通过泛素蛋白酶体途径降低 BRD7 蛋白的稳定性,通过激活 YB1/Bcl-2 转录轴促进乳腺癌进展和紫杉醇耐药性。

Xue Changning, Wei Qingqing, Li Mengna, Wei Jianxia, Zheng Lemei, Wu Zubing, Xin Huizhen, Duan Yumei, Fan Songqing, Xiong Wei, Li Guiyuan, Tang Faqing, Deng Hongyu, Zhou Ming

Tumor- and host-derived heparanase-2 (Hpa2) attenuates tumorigenicity: role of Hpa2 in macrophage polarization and BRD7 nuclear localization

肿瘤和宿主来源的肝素酶-2 (Hpa2) 可减弱肿瘤发生:Hpa2 在巨噬细胞极化和 BRD7 核定位中的作用

Soboh, Soaad; Vorontsova, Avital; Farhoud, Malik; Barash, Uri; Naroditsky, Inna; Gross-Cohen, Miriam; Weissmann, Marina; Nishioka, Yasuhiko; Woolf, Adrian S; Roberts, Neil A; Shaked, Yuval; Ilan, Neta; Vlodavsky, Israel

BRD7 as key factor in PBAF complex assembly and CD8+ T cell differentiation

BRD7 是 PBAF 复合物组装和 CD8+ T 细胞分化的关键因素

Feng Huang, Yingtong Lin, Yidan Qiao, Yaochang Yuan, Zhihan Zhong, Baohong Luo, Yating Wu, Jun Liu, Jingliang Chen, Wanying Zhang, Hui Zhang, Bingfeng Liu

TRIM28 promotes tumor growth and metastasis in breast cancer by targeting the BRD7 protein for ubiquitination and degradation

TRIM28 通过靶向 BRD7 蛋白进行泛素化和降解,从而促进乳腺癌的肿瘤生长和转移。

Xue, Changning; Meng, Hanbing; Niu, Weihong; Li, Mengna; Wei, Jianxia; Chen, Shipeng; Zheng, Lemei; Duan, Yumei; Deng, Hongyu; Tang, Faqing; Fan, Songqing; Tan, Ming; Xiong, Wei; Zhou, Ming

Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer

选择性BRD7溴结构域抑制剂的合理设计与开发及其在前列腺癌中的活性

Sandra C Ordonez-Rubiano ,Chad A Maschinot ,Sijie Wang ,Surbhi Sood ,Luisa F Baracaldo-Lancheros ,Brayden P Strohmier ,Alexander J McQuade ,Brian C Smith ,Emily C Dykhuizen

SMARCB1 Loss in Poorly Differentiated Chordomas Drives Tumor Progression

SMARCB1缺失在低分化脊索瘤中驱动肿瘤进展

Tara A Walhart ,Bryanna Vacca ,Austin J Hepperla ,Samera H Hamad ,James Petrongelli ,Yemin Wang ,Erin L McKean ,Michelle Moksa ,Qi Cao ,Stephen Yip ,Martin Hirst ,Bernard E Weissman

Identification of BRD7 by whole-exome sequencing as a predictor for intermediate-stage hepatocellular carcinoma in patients undergoing TACE

通过全外显子组测序鉴定BRD7,可作为接受TACE治疗患者中期肝细胞癌的预测因子。

Huang, Kun; Wu, Yanqin; Fan, Wenzhe; Zhao, Yue; Xue, Miao; Liu, Haikuan; Tang, Yiyang; Li, Jiaping